Browsing Harvard Medical School by Keyword "Alzheimer pathology"

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    • Inositol Trisphosphate 3-Kinase B Is Increased in Human Alzheimer Brain and Exacerbates Mouse Alzheimer Pathology 

      Stygelbout, Virginie; Leroy, Karelle; Pouillon, Valerie; Ando, Kunie; D’Amico, Eva; Jia, Yonghui; Luo, Hongbo; Duyckaerts, Charles; Erneux, Christophe; Schurmans, Stephane; Brion, Jean-Pierre (Oxford University Press (OUP), 2014)
      ITPKB phosphorylates inositol 1,4,5-trisphosphate into inositol 1,3,4,5-tetrakisphosphate and controls signal transduction in various hematopoietic cells. Surprisingly, it has been reported that the ITPKB messenger RNA ...