Browsing Harvard Medical School by Keyword "Zinc"
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Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins
(Public Library of Science, 2016)Zinc binding domains are common and versatile protein structural motifs that mediate diverse cellular functions. Among the many structurally distinct families of zinc finger (ZnF) proteins, the AN1 domain remains poorly ... -
Subtype-specific accumulation of intracellular zinc pools is associated with the malignant phenotype in breast cancer
(BioMed Central, 2016)Background: Zinc (Zn) hyper-accumulates in breast tumors and malignant cell lines compared to normal mammary epithelium. The mechanisms responsible for Zn accumulation and the consequence of Zn dysregulation are poorly ...