Browsing Harvard Medical School by Keyword "acetylation"

Now showing items 1-2 of 2

    • Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2 

      Wang, Zhiwei; Inuzuka, Hiroyuki; Zhong, Jiateng; Liu, Pengda; Sarkar, Fazlul H.; Sun, Yi; Wei, Wenyi (Impact Journals LLC, 2012)
      The Skp2 (S-phase kinase associated protein 2) oncoprotein is often highly expressed in various types of human cancers. However, the mechanistic basis of its oncogenic function, as well as the upstream regulatory pathway(s) ...

    • Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy 

      Chen, Jing; Michan, Shaday; Juan, Aimee M.; Hurst, Christian G.; Hatton, Colman J.; Pei, Dorothy T.; Joyal, Jean-Sebastien; Evans, Lucy P.; Cui, Zhenghao; Stahl, Andreas; Sapieha, Przemyslaw; Sinclair, David Andrew; Smith, Lois Elaine Hodgson (Springer Science + Business Media, 2013)
      Regeneration of blood vessels in ischemic neuronal tissue is critical to reduce tissue damage in diseases. In proliferative retinopathy, initial vessel loss leads to retinal ischemia, which can induce either regrowth of ...