Browsing Harvard Medical School by Keyword "aggregates"
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The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells
(Impact Journals LLC, 2014)Velcade is one of the inescapable drug to treat patient suffering from multiple myeloma (MM) and resistance to this drug represents a major drawback for patients. However, the mechanisms underlying velcade resistance remain ... -
Toxic Metals in Aquatic Ecosystems: A Microbiological Perspective
(The National Institute of Environmental Health Sciences, 1995)Microbe-metal interactions in aquatic environments and their exact role in transport and transformations of toxic metals are poorly understood. This paper will briefly review our understanding of these interactions. Ongoing ...