Browsing Harvard Medical School by Keyword "body mass index"

Now showing items 1-14 of 14

    • A NOVEL BIOMARKER IN ACUTE HEART FAILURE AND OBESITY PARADOX IN ACUTE MEDICAL ILLNESS 

      KALAYCI KARABAY, ARZU (2021-06-23)
      Each year, approximately 8 million patients in the United States and 12 million patients in the European countries are hospitalized for acute medical illnesses such as heart failure, pneumonia, and stroke. VTE is an important ...

    • Association of body mass index and waist circumference with successful ageing: 16 year follow-up of the Whitehall II study 

      Singh-Manoux, Archana; Sabia, Séverine; Bouillon, Kim; Brunner, Eric J; Grodstein, Francine; Elbaz, Alexis; Kivimaki, Mika (2013)
      Objective: We examined whether midlife body mass index (BMI) and waist circumference (WC) predict successful ageing. Design and Methods BMI/WC were assessed in 4869 persons (mean age 51.2, range 42–63 in 1991/93) and ...

    • Association of Body Mass Index in Early Adulthood and Middle Age with Future Site-Specific Cancer Mortality: The Harvard Alumni Health Study 

      Gray, L.; Lee, I-Min; Sesso, Howard David; Batty, G. D. (Oxford University Press, 2012)
      Background:: The association between adiposity in early adulthood and subsequent development of specific malignancies is unclear. Further, the potential for mediation by adiposity in middle age has not been well examined. ...

    • Does Being Overweight Really Reduce Mortality? 

      Tobias, Deirdre K.; Hu, Frank B. (2013)
      There is indisputable evidence from epidemiologic and clinical studies that being overweight and obese elevates the risk of developing debilitating and costly chronic diseases, including hypertension, hypercholesterolemia, ...

    • A genome-wide association study of anorexia nervosa 

      Boraska, Vesna; Franklin, Christopher S; Floyd, James AB; Thornton, Laura M; Huckins, Laura M; Southam, Lorraine; Rayner, N William; Tachmazidou, Ioanna; Klump, Kelly L; Treasure, Janet; Lewis, Cathryn M; Schmidt, Ulrike; Tozzi, Federica; Kiezebrink, Kirsty; Hebebrand, Johannes; Gorwood, Philip; Adan, Roger AH; Kas, Martien JH; Favaro, Angela; Santonastaso, Paolo; Fernández-Aranda, Fernando; Gratacos, Monica; Rybakowski, Filip; Dmitrzak-Weglarz, Monika; Kaprio, Jaakko; Keski-Rahkonen, Anna; Raevuori, Anu; Van Furth, Eric F; Slof-Op t Landt, Margarita CT; Hudson, James I; Reichborn-Kjennerud, Ted; Knudsen, Gun Peggy S; Monteleone, Palmiero; Kaplan, Allan S; Karwautz, Andreas; Hakonarson, Hakon; Berrettini, Wade H; Guo, Yiran; Li, Dong; Schork, Nicholas J.; Komaki, Gen; Ando, Tetsuya; Inoko, Hidetoshi; Esko, Tõnu; Fischer, Krista; Männik, Katrin; Metspalu, Andres; Baker, Jessica H; Cone, Roger D; Dackor, Jennifer; DeSocio, Janiece E; Hilliard, Christopher E; O’Toole, Julie K; Pantel, Jacques; Szatkiewicz, Jin P; Taico, Chrysecolla; Zerwas, Stephanie; Trace, Sara E; Davis, Oliver SP; Helder, Sietske; Bühren, Katharina; Burghardt, Roland; de Zwaan, Martina; Egberts, Karin; Ehrlich, Stefan; Herpertz-Dahlmann, Beate; Herzog, Wolfgang; Imgart, Hartmut; Scherag, André; Scherag, Susann; Zipfel, Stephan; Boni, Claudette; Ramoz, Nicolas; Versini, Audrey; Brandys, Marek K; Danner, Unna N; de Kovel, Carolien; Hendriks, Judith; Koeleman, Bobby PC; Ophoff, Roel A; Strengman, Eric; van Elburg, Annemarie A; Bruson, Alice; Clementi, Maurizio; Degortes, Daniela; Forzan, Monica; Tenconi, Elena; Docampo, Elisa; Escaramís, Geòrgia; Jiménez-Murcia, Susana; Lissowska, Jolanta; Rajewski, Andrzej; Szeszenia-Dabrowska, Neonila; Slopien, Agnieszka; Hauser, Joanna; Karhunen, Leila; Meulenbelt, Ingrid; Slagboom, P Eline; Tortorella, Alfonso; Maj, Mario; Dedoussis, George; Dikeos, Dimitris; Gonidakis, Fragiskos; Tziouvas, Konstantinos; Tsitsika, Artemis; Papezova, Hana; Slachtova, Lenka; Martaskova, Debora; Kennedy, James L.; Levitan, Robert D.; Yilmaz, Zeynep; Huemer, Julia; Koubek, Doris; Merl, Elisabeth; Wagner, Gudrun; Lichtenstein, Paul; Breen, Gerome; Cohen-Woods, Sarah; Farmer, Anne; McGuffin, Peter; Cichon, Sven; Giegling, Ina; Herms, Stefan; Rujescu, Dan; Schreiber, Stefan; Wichmann, H-Erich; Dina, Christian; Sladek, Rob; Gambaro, Giovanni; Soranzo, Nicole; Julia, Antonio; Marsal, Sara; Rabionet, Raquel; Gaborieau, Valerie; Dick, Danielle M; Palotie, Aarno; Ripatti, Samuli; Widén, Elisabeth; Andreassen, Ole A; Espeseth, Thomas; Lundervold, Astri; Reinvang, Ivar; Steen, Vidar M; Le Hellard, Stephanie; Mattingsdal, Morten; Ntalla, Ioanna; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Navratilova, Marie; Gallinger, Steven; Pinto, Dalila; Scherer, Stephen; Aschauer, Harald; Carlberg, Laura; Schosser, Alexandra; Alfredsson, Lars; Ding, Bo; Klareskog, Lars; Padyukov, Leonid; Finan, Chris; Kalsi, Gursharan; Roberts, Marion; Logan, Darren W; Peltonen, Leena; Ritchie, Graham RS; Barrett, Jeffrey C; Estivill, Xavier; Hinney, Anke; Sullivan, Patrick F; Collier, David A; Zeggini, Eleftheria; Bulik, Cynthia M (2013)
      Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by dangerously low body weight. Neither candidate gene studies nor an initial genome wide association study (GWAS) have yielded significant and ...

    • The Gut Microbiome Contributes to a Substantial Proportion of the Variation in Blood Lipids 

      Fu, Jingyuan; Bonder, Marc Jan; Cenit, María Carmen; Tigchelaar, Ettje F.; Maatman, Astrid; Dekens, Jackie A.M.; Brandsma, Eelke; Marczynska, Joanna; Imhann, Floris; Weersma, Rinse K.; Franke, Lude; Poon, Tiffany W.; Xavier, Ramnik J.; Gevers, Dirk; Hofker, Marten H.; Wijmenga, Cisca; Zhernakova, Alexandra (Lippincott Williams & Wilkins, 2015)
      Rationale: Evidence suggests that the gut microbiome is involved in the development of cardiovascular disease, with the host–microbe interaction regulating immune and metabolic pathways. However, there was no firm evidence ...

    • Major Dietary Patterns in Relation to General and Central Obesity among Chinese Adults 

      Yu, Canqing; Shi, Zumin; Lv, Jun; Du, Huaidong; Qi, Lu; Guo, Yu; Bian, Zheng; Chang, Liang; Tang, Xuefeng; Jiang, Qilian; Mu, Huaiyi; Pan, Dongxia; Chen, Junshi; Chen, Zhengming; Li, Liming (MDPI, 2015)
      Limited evidence exists for the association between diet pattern and obesity phenotypes among Chinese adults. In the present study, we analyzed the cross-sectional data from 474,192 adults aged 30–79 years from the China ...

    • Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients 

      Berg, Anna; Hoivik, Erling A.; Mjøs, Siv; Holst, Frederik; Werner, Henrica M. J.; Tangen, Ingvild L.; Taylor-Weiner, Amaro; Gibson, William J.; Kusonmano, Kanthida; Wik, Elisabeth; Trovik, Jone; Halle, Mari K.; Øyan, Anne M.; Kalland, Karl-Henning; Cherniack, Andrew D.; Beroukhim, Rameen; Stefansson, Ingunn; Mills, Gordon B.; Krakstad, Camilla; Salvesen, Helga B. (Impact Journals LLC, 2015)
      Obesity is linked to increased incidence of endometrioid endometrial cancer (EEC) and complex atypical hyperplasia (CAH). We here explore pattern and sequence of molecular alterations characterizing endometrial carcinogenesis ...

    • Neighborhood Self-Selection: The Role of Pre-Move Health Factors on the Built and Socioeconomic Environment 

      James, Peter; Hart, Jaime E.; Arcaya, Mariana C.; Feskanich, Diane; Laden, Francine; Subramanian, S.V. (MDPI, 2015)
      Residential self-selection bias is a concern in studies of neighborhoods and health. This bias results from health behaviors predicting neighborhood choice. To quantify this bias, we examined associations between pre-move ...

    • Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium 

      Olsen, C. M.; Nagle, C. M.; Whiteman, D. C.; Ness, R.; Pearce, C. L.; Pike, M. C.; Rossing, M. A.; Terry, Kathryn Lynne; Wu, A. H.; Risch, H. A.; Yu, H.; Doherty, J. A.; Chang-Claude, J.; Hein, R.; Nickels, S.; Wang-Gohrke, S.; Goodman, M. T.; Carney, M. E.; Matsuno, R. K.; Lurie, G.; Moysich, K.; Kjaer, S. K.; Jensen, A.; Hogdall, E.; Goode, E. L.; Fridley, B. L.; Vierkant, R. A.; Larson, M. C.; Schildkraut, J.; Hoyo, C.; Moorman, P.; Weber, R. P.; Cramer, Daniel William; Vitonis, A. F.; Bandera, E. V.; Olson, S. H.; Rodriguez-Rodriguez, L.; King, M.; Brinton, L. A.; Yang, H.; Garcia-Closas, M.; Lissowska, J.; Anton-Culver, H.; Ziogas, A.; Gayther, S. A.; Ramus, S. J.; Menon, U.; Gentry-Maharaj, A.; Webb, P. M. (BioScientifica, 2013)
      Whilst previous studies have reported that higher body-mass index (BMI) increases a woman’s risk of developing ovarian cancer, associations for the different histological subtypes have not been well defined. As the prevalence ...

    • Optimal body weight for health and longevity: bridging basic, clinical, and population research 

      Fontana, Luigi; Hu, Frank B (BlackWell Publishing Ltd, 2014)
      Excess body weight and adiposity cause insulin resistance, inflammation, and numerous other alterations in metabolic and hormonal factors that promote atherosclerosis, tumorigenesis, neurodegeneration, and aging. Studies ...

    • Optimism and the Socioeconomic Status Gradient in Adolescent Adiposity 

      Khullar, Dhruv; Oreskovic, Nicolas Michel; Perrin, James Marc; Goodman, Elizabeth (Elsevier BV, 2011)
      Purpose: To assess if dispositional optimism is associated with adiposity and explore if dispositional optimism mediates the relationship between parent education and adiposity (BMI z score). Methods: Multivariable regression ...

    • Pregnancy urinary phthalate metabolite concentrations and gestational diabetes risk factors 

      James-Todd, Tamarra; Meeker, John D.; Huang, Tianyi; Hauser, Russ B.; Ferguson, Kelly K.; Rich-Edwards, Janet Wilson; McElrath, Thomas Frederick; Seely, Ellen Wells (Elsevier BV, 2016)
      Background: Epidemiologic studies suggest phthalate metabolite concentrations are associated with type 2 diabetes. GDM is a strong risk factor for type 2 diabetes. Little is known about phthalates and GDM risk factors (i.e. ...

    • Prospective associations of parental smoking, alcohol use, marital status, maternal satisfaction, and parental and childhood body mass index at 6.5 years with later problematic eating attitudes 

      Wade, K H; Skugarevsky, O; Kramer, M S; Patel, R; Bogdanovich, N; Vilchuck, K; Sergeichick, N; Richmond, R; Palmer, T; Davey Smith, G; Gillman, M; Oken, E; Martin, R M (Nature Publishing Group, 2014)
      Background: Few studies have prospectively investigated whether early-life exposures are associated with pre-adolescent eating attitudes. Objective: The objective of this study is to prospectively investigate associations ...