Browsing Harvard Medical School by Keyword "brain tumors"

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    • A STAT3 Gene Expression Signature in Gliomas is Associated with a Poor Prognosis 

      Alvarez, James V.; Mukherjee, Neelanjan; Chakravarti, Arnab; Robe, Pierre; Zhai, Gary; Chakladar, Abhijit; Loeffler, Jay S; Black, Peter McLaren; Frank, David A. (Libertas Academica, 2007)
      Gliomas frequently display constitutive activation of the transcription factor STAT3, a protein that is known to be able to mediate neoplastic transformation. STAT3 regulates genes that play a central role in cellular ...