Browsing Harvard Medical School by Keyword "cAMP/PKA signaling"
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A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved in systemic and synaptic growth
(Landes Bioscience, 2014)Neurofibromatosis type 1 (NF1) is caused by loss of a negative regulator of Ras oncoproteins. Unknown genetic modifiers have been implicated in NF1’s characteristic variability. Drosophila melanogaster dNf1 phenotypes ...