Browsing Harvard Medical School by Keyword "cancer stem cell"

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    • Sox2 maintains self-renewal of tumor initiating cells in osteosarcomas 

      Basu-Roy, Upal; Seo, Eunjeong; Ramanathapuram, Lalitha; Rapp, Timothy B.; Perry, Jennifer; Orkin, Stuart Holland; Mansukhani, Alka; Basilico, Claudio (2011)
      Tumors are thought to be sustained by a reservoir of self-renewing cells, termed tumor initiating cells or cancer stem cells. Osteosarcomas are high-grade sarcomas derived from osteoblast progenitor cells and are the most ...