Browsing Harvard Medical School by Keyword "chronic obstructive pulmonary disease"
Now showing items 1-8 of 8
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Association of IREB2 and CHRNA3 Polymorphisms with Airflow Obstruction in Severe Alpha-1 Antitrypsin Deficiency
(BioMed Central, 2012)Background: The development of COPD in subjects with alpha-1 antitrypsin (AAT) deficiency is likely to be influenced by modifier genes. Genome-wide association studies and integrative genomics approaches in COPD have ... -
Chronic Obstructive Pulmonary Disease Mortality in Diesel-Exposed Railroad Workers
(National Institute of Environmental Health Sciences, 2006)Diesel exhaust is a mixture of combustion gases and ultrafine particles coated with organic compounds. There is concern whether exposure can result in or worsen obstructive airway diseases, but there is only limited ... -
Elevated plasma levels of pigment epithelium-derived factor correlated with inflammation and lung function in COPD patients
(Dove Medical Press, 2015)Rationale: Pigment epithelium-derived factor (PEDF) is a 50 kD small secreting glycoprotein that participates in multiple physiological and pathological processes. Recent studies have reported that PEDF plays an important ... -
The Global Contribution of Outdoor Air Pollution to the Incidence, Prevalence, Mortality and Hospital Admission for Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis
(MDPI, 2014)Objective:: This study aimed to investigate the quantitative effects of outdoor air pollution, represented by 10 µg/m3 increment of PM10, on chronic obstructive pulmonary disease in China, United States and European Union ... -
Improved care of acute exacerbation of chronic obstructive pulmonary disease in two academic emergency departments
(Springer-Verlag, 2009)Background: Although several chronic obstructive pulmonary disease (COPD) practice guidelines have been published, there is sparse data on the actual emergency department (ED) management of acute exacerbation of COPD ... -
The Relationship Between Ambient Air Pollution and Heart Rate Variability Differs for Individuals with Heart and Pulmonary Disease
(National Institute of Environmental Health Sciences, 2005)Associations between concentrations of ambient fine particles [particulate matter < 2.5 μm aerodynamic diameter (PM\(_{2.5}\))] and heart rate variability (HRV) have differed by study population. We examined the effects ... -
Tai chi mind-body exercise in patients with COPD: study protocol for a randomized controlled trial
(BioMed Central, 2014)Background: Chronic obstructive pulmonary disease (COPD) is a chronic, progressively debilitating condition that is prevalent in the US and worldwide. Patients suffer from progressive dyspnea and exercise intolerance. ... -
Variable DNA Methylation Is Associated with Chronic Obstructive Pulmonary Disease and Lung Function
(American Thoracic Society, 2012)Rationale: Chronic obstructive pulmonary disease (COPD) is associated with local (lung) and systemic (blood) inflammation and manifestations. DNA methylation is an important regulator of gene transcription, and global and ...