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Increased Gray Matter Diffusion Anisotropy in Patients with Persistent Post-Concussive Symptoms following Mild Traumatic Brain Injury
(Public Library of Science, 2013)
A significant percentage of individuals diagnosed with mild traumatic brain injury (mTBI) experience persistent post-concussive symptoms (PPCS). Little is known about the pathology of these symptoms and there is often no ...
Analysis of schizophrenia-related genes and electrophysiological measures reveals ZNF804A association with amplitude of P300b elicited by novel sounds
(Nature Publishing Group, 2014)
Several genes have recently been identified as risk factors for schizophrenia (SZ) by genome-wide association studies (GWAS), including ZNF804A which is thought to function in transcriptional regulation. However, the ...
Localized abnormalities in the cingulum bundle in patients with schizophrenia: A Diffusion Tensor tractography study
(Elsevier, 2014)
The cingulum bundle (CB) connects gray matter structures of the limbic system and as such has been implicated in the etiology of schizophrenia. There is growing evidence to suggest that the CB is actually comprised of a ...
Resting-State Brain Functional Connectivity Is Altered in Type 2 Diabetes
(American Diabetes Association, 2012)
Type 2 diabetes mellitus (T2DM) is a risk factor for Alzheimer disease (AD). Populations at risk for AD show altered brain activity in the default mode network (DMN) before cognitive dysfunction. We evaluated this brain ...
Diffusion Tensor Imaging, Structural Connectivity, and Schizophrenia
(Hindawi Publishing Corporation, 2011)
A fundamental tenet of the “disconnectivity” theories of schizophrenia is that the disorder is ultimately caused by abnormal communication between spatially disparate brain structures. Given that the white matter fasciculi ...
Oligodendrocytes in Schizophrenia
(Hindawi Publishing Corporation, 2011)
Genetic contributions to changes of fiber tracts of ventral visual stream in 22q11.2 deletion syndrome
(Springer Science + Business Media, 2013)
Patients with 22q11.2 deletion syndrome (22q11.2DS) represent a population at high risk for
developing schizophrenia, as well as learning disabilities. Deficits in visuo-spatial memory are
thought to underlie some of the ...
Maximum Entropy Estimation of Glutamate and Glutamine in MR Spectroscopic Imaging
(Springer Science + Business Media, 2014)
Magnetic resonance spectroscopic imaging (MRSI) is often used to estimate the concentration of several brain metabolites. Abnormalities in these concentrations can indicate specific pathology, which can be quite useful in ...
Fiber geometry in the corpus callosum in schizophrenia: Evidence for transcallosal misconnection
(Elsevier BV, 2011)
Background—Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of ...
Estimation of Extracellular Volume from Regularized Multi-shell Diffusion MRI
(Springer Science + Business Media, 2012)
Diffusion MRI measures micron scale displacement of water molecules, providing unique insight into microstructural tissue architecture. However, current practical image resolution is in the millimeter scale, and thus ...