Browsing HMS Scholarly Articles by Author "Prywes, Noam"
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Nonenzymatic copying of RNA templates containing all four letters is catalyzed by activated oligonucleotides
Prywes, Noam; Blain, J Craig; Del Frate, Francesca; Szostak, Jack W (eLife Sciences Publications, Ltd, 2016)The nonenzymatic replication of RNA is a potential transitional stage between the prebiotic chemistry of nucleotide synthesis and the canonical RNA world in which RNA enzymes (ribozymes) catalyze replication of the RNA ...