Browsing HMS Scholarly Articles by Author "Evans, Lucy P."

Now showing items 1-3 of 3

    • Choroid Sprouting Assay: An Ex Vivo Model of Microvascular Angiogenesis 

      Shao, Zhuo; Friedlander, Mollie; Hurst, Christian G.; Cui, Zhenghao; Pei, Dorothy T.; Evans, Lucy P.; Juan, Aimee M.; Tahir, Houda; Duhamel, François; Chen, Jing; Sapieha, Przemyslaw; Chemtob, Sylvain; Joyal, Jean-Sébastien; Smith, Lois E. H. (Public Library of Science, 2013)
      Angiogenesis of the microvasculature is central to the etiology of many diseases including proliferative retinopathy, age-related macular degeneration and cancer. A mouse model of microvascular angiogenesis would be very ...

    • Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy 

      Chen, Jing; Michan, Shaday; Juan, Aimee M.; Hurst, Christian G.; Hatton, Colman J.; Pei, Dorothy T.; Joyal, Jean-Sebastien; Evans, Lucy P.; Cui, Zhenghao; Stahl, Andreas; Sapieha, Przemyslaw; Sinclair, David Andrew; Smith, Lois Elaine Hodgson (Springer Science + Business Media, 2013)
      Regeneration of blood vessels in ischemic neuronal tissue is critical to reduce tissue damage in diseases. In proliferative retinopathy, initial vessel loss leads to retinal ischemia, which can induce either regrowth of ...

    • Sirtuin1 Over-Expression Does Not Impact Retinal Vascular and Neuronal Degeneration in a Mouse Model of Oxygen-Induced Retinopathy 

      Michan, Shaday; Juan, Aimee M.; Hurst, Christian G.; Cui, Zhenghao; Evans, Lucy P.; Hatton, Colman J.; Pei, Dorothy T.; Ju, Meihua; Sinclair, David A.; Smith, Lois E. H.; Chen, Jing (Public Library of Science, 2014)
      Proliferative retinopathy is a leading cause of blindness, including retinopathy of prematurity (ROP) in children and diabetic retinopathy in adults. Retinopathy is characterized by an initial phase of vessel loss, leading ...