Browsing HMS Scholarly Articles by Author "Iakoubova, Olga A."

Now showing items 1-1 of 1

    • Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy 

      Shiffman, Dov; Trompet, Stella; Louie, Judy Z.; Rowland, Charles M.; Catanese, Joseph J.; Iakoubova, Olga A.; Kirchgessner, Todd G.; Westendorp, Rudi G. J.; de Craen, Anton J. M.; Slagboom, P. Eline; Buckley, Brendan M.; Stott, David J.; Sattar, Naveed; Devlin, James J.; Packard, Christopher J.; Ford, Ian; Jukema, J. Wouter; Sacks, Frank Martin (Public Library of Science, 2012)
      Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood. We have investigated the effect of genetic variation on the ...