Browsing HMS Scholarly Articles by Author "Curto, Martina"

Now showing items 1-3 of 3

    • Altered kynurenine pathway metabolites in serum of chronic migraine patients 

      Curto, Martina; Lionetto, Luana; Negro, Andrea; Capi, Matilde; Fazio, Francesco; Giamberardino, Maria Adele; Simmaco, Maurizio; Nicoletti, Ferdinando; Martelletti, Paolo (Springer Milan, 2016)
      Background: Activation of glutamate (Glu) receptors plays a key role in the pathophysiology of migraine. Both NMDA and metabotropic Glu receptors are activated or inhibited by metabolites of the kynurenine pathway, such ...

    • Altered serum levels of kynurenine metabolites in patients affected by cluster headache 

      Curto, Martina; Lionetto, Luana; Negro, Andrea; Capi, Matilde; Perugino, Francesca; Fazio, Francesco; Giamberardino, Maria Adele; Simmaco, Maurizio; Nicoletti, Ferdinando; Martelletti, Paolo (Springer Milan, 2016)
      Background: The reported efficacy of memantine in the treatment of patients with cluster headache (CH) suggests that NMDA receptors are involved in mechanisms of nociceptive sensitization within the trigeminal system ...

    • OnabotulinumtoxinA 155 U in medication overuse headache: a two years prospective study 

      Negro, Andrea; Curto, Martina; Lionetto, Luana; Crialesi, Dorotea; Martelletti, Paolo (Springer International Publishing, 2015)
      The efficacy and safety of OnabotulinumtoxinA 155-195 U (BOTOX®) in adults with chronic migraine (CM) were demonstrated in both the Phase III Research Evaluating Migraine Prophylaxis Therapy (PREEMPT) studies. However, ...