Browsing HMS Scholarly Articles by Author "Xi, Yuanxin"

Now showing items 1-2 of 2

    • Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications 

      Harris, R Alan; Wang, Ting; Coarfa, Cristian; Nagarajan, Raman P; Hong, Chibo; Downey, Sara L; Johnson, Brett E; Fouse, Shaun D; Delaney, Allen; Zhao, Yongjun; Olshen, Adam; Ballinger, Tracy; Zhou, Xin; Forsberg, Kevin J; Gu, Junchen; Echipare, Lorigail; O, Henriette; Lister, Ryan; Pelizzola, Mattia; Xi, Yuanxin; Epstein, Charles B; Bernstein, Bradley E.; Hawkins, R David; Ren, Bing; Chung, Wen-Yu; Gu, Hongcang; Bock, Christoph; Gnirke, Andreas; Zhang, Michael Q; Haussler, David; Ecker, Joseph R; Li, Wei; Farnham, Peggy J; Waterland, Robert A; Meissner, Alexander; Marra, Marco A; Hirst, Martin; Milosavljevic, Aleksandar; Costello, Joseph F (Nature Publishing Group, 2010)
      Sequencing-based DNA methylation profiling methods are comprehensive and, as accuracy and affordability improve, will increasingly supplant microarrays for genome-scale analyses. Here, four sequencing-based methodologies ...

    • SIRT7 Links H3K18 Deacetylation to Maintenance of Oncogenic Transformation 

      Barber, Matthew F.; Michishita-Kioi, Eriko; Xi, Yuanxin; Tasselli, Luisa; Kioi, Mitomu; Moqtaderi, Zarmik; Tennen, Ruth I.; Paredes, Silvana; Young, Nicolas L.; Chen, Kaifu; Struhl, Kevin; Garcia, Benjamin A.; Gozani, Or; Li, Wei; Chua, Katrin F. (2012)
      Sirtuin proteins regulate diverse cellular pathways that influence genomic stability, metabolism, and ageing. SIRT7 is a mammalian sirtuin whose biochemical activity, molecular targets, and physiologic functions have been ...