Browsing HMS Scholarly Articles by Author "Jabado, Nada"

Now showing items 1-4 of 4

    • MYB-QKI rearrangements in Angiocentric Glioma drive tumorigenicity through a tripartite mechanism 

      Bandopadhayay, Pratiti; Ramkissoon, Lori A.; Jain, Payal; Bergthold, Guillaume; Wala, Jeremiah; Zeid, Rhamy; Schumacher, Steven E.; Urbanski, Laura; O’Rourke, Ryan; Gibson, William J.; Pelton, Kristine; Ramkissoon, Shakti H.; Han, Harry J.; Zhu, Yuankun; Choudhari, Namrata; Silva, Amanda; Boucher, Katie; Henn, Rosemary E.; Kang, Yun Jee; Knoff, David; Paolella, Brenton R.; Gladden-Young, Adrianne; Varlet, Pascale; Pages, Melanie; Horowitz, Peleg M.; Federation, Alexander; Malkin, Hayley; Tracy, Adam; Seepo, Sara; Ducar, Matthew; Hummelen, Paul Van; Santi, Mariarita; Buccoliero, Anna Maria; Scagnet, Mirko; Bowers, Daniel C.; Giannini, Caterina; Puget, Stephanie; Hawkins, Cynthia; Tabori, Uri; Klekner, Almos; Bognar, Laszlo; Burger, Peter C.; Eberhart, Charles; Rodriguez, Fausto J.; Hill, D. Ashley; Mueller, Sabine; Haas-Kogan, Daphne A.; Phillips, Joanna J.; Santagata, Sandro; Stiles, Charles D.; Bradner, James E.; Jabado, Nada; Goren, Alon; Grill, Jacques; Ligon, Azra H.; Goumnerova, Liliana; Waanders, Angela J.; Storm, Phillip B.; Kieran, Mark W.; Ligon, Keith L.; Beroukhim, Rameen; Resnick, Adam C. (2016)
      Angiocentric gliomas are pediatric low-grade gliomas (PLGGs) without known recurrent genetic drivers. We performed genomic analysis of new and published data from 249 PLGGs including 19 Angiocentric Gliomas. We identified ...

    • Specific detection of methionine 27 mutation in histone 3 variants (H3K27M) in fixed tissue from high-grade astrocytomas 

      Bechet, Denise; Gielen, Gerrit G. H.; Korshunov, Andrey; Pfister, Stefan M.; Rousso, Caterina; Faury, Damien; Fiset, Pierre-Olivier; Benlimane, Naciba; Lewis, Peter W.; Lu, Chao; David Allis, C.; Kieran, Mark W.; Ligon, Keith L.; Pietsch, Torsten; Ellezam, Benjamin; Albrecht, Steffen; Jabado, Nada (Springer Berlin Heidelberg, 2014)
      Studies in pediatric high-grade astrocytomas (HGA) by our group and others have uncovered recurrent somatic mutations affecting highly conserved residues in histone 3 (H3) variants. One of these mutations leads to analogous ...

    • TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma 

      Remke, Marc; Ramaswamy, Vijay; Peacock, John; Shih, David J. H.; Koelsche, Christian; Northcott, Paul A.; Hill, Nadia; Cavalli, Florence M. G.; Kool, Marcel; Wang, Xin; Mack, Stephen C.; Barszczyk, Mark; Morrissy, A. Sorana; Wu, Xiaochong; Agnihotri, Sameer; Luu, Betty; Jones, David T. W.; Garzia, Livia; Dubuc, Adrian M.; Zhukova, Nataliya; Vanner, Robert; Kros, Johan M.; French, Pim J.; Van Meir, Erwin G.; Vibhakar, Rajeev; Zitterbart, Karel; Chan, Jennifer A.; Bognár, László; Klekner, Almos; Lach, Boleslaw; Jung, Shin; Saad, Ali G.; Liau, Linda M.; Albrecht, Steffen; Zollo, Massimo; Cooper, Michael K.; Thompson, Reid C.; Delattre, Oliver O.; Bourdeaut, Franck; Doz, François F.; Garami, Miklós; Hauser, Peter; Carlotti, Carlos G.; Van Meter, Timothy E.; Massimi, Luca; Fults, Daniel; Pomeroy, Scott L.; Kumabe, Toshiro; Ra, Young Shin; Leonard, Jeffrey R.; Elbabaa, Samer K.; Mora, Jaume; Rubin, Joshua B.; Cho, Yoon-Jae; McLendon, Roger E.; Bigner, Darell D.; Eberhart, Charles G.; Fouladi, Maryam; Wechsler-Reya, Robert J.; Faria, Claudia C.; Croul, Sidney E.; Huang, Annie; Bouffet, Eric; Hawkins, Cynthia E.; Dirks, Peter B.; Weiss, William A.; Schüller, Ulrich; Pollack, Ian F.; Rutkowski, Stefan; Meyronet, David; Jouvet, Anne; Fèvre-Montange, Michelle; Jabado, Nada; Perek-Polnik, Marta; Grajkowska, Wieslawa A.; Kim, Seung-Ki; Rutka, James T.; Malkin, David; Tabori, Uri; Pfister, Stefan M.; Korshunov, Andrey; von Deimling, Andreas; Taylor, Michael D. (Springer Berlin Heidelberg, 2013)
      Telomerase reverse transcriptase (TERT) promoter mutations were recently shown to drive telomerase activity in various cancer types, including medulloblastoma. However, the clinical and biological implications of TERT ...

    • WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma 

      Zhukova, Nataliya; Ramaswamy, Vijay; Remke, Marc; Martin, Dianna C; Castelo-Branco, Pedro; Zhang, Cindy H; Fraser, Michael; Tse, Ken; Poon, Raymond; Shih, David JH; Baskin, Berivan; Ray, Peter N; Bouffet, Eric; Dirks, Peter; von Bueren, Andre O; Pfaff, Elke; Korshunov, Andrey; Jones, David TW; Northcott, Paul A; Kool, Marcel; Pugh, Trevor J; Pomeroy, Scott L; Cho, Yoon-Jae; Pietsch, Torsten; Gessi, Marco; Rutkowski, Stefan; Bognár, Laszlo; Cho, Byung-Kyu; Eberhart, Charles G; Conter, Cecile Faure; Fouladi, Maryam; French, Pim J; Grajkowska, Wieslawa A; Gupta, Nalin; Hauser, Peter; Jabado, Nada; Vasiljevic, Alexandre; Jung, Shin; Kim, Seung-Ki; Klekner, Almos; Kumabe, Toshihiro; Lach, Boleslaw; Leonard, Jeffrey R; Liau, Linda M; Massimi, Luca; Pollack, Ian F; Ra, Young Shin; Rubin, Joshua B; Van Meir, Erwin G; Wang, Kyu-Chang; Weiss, William A; Zitterbart, Karel; Bristow, Robert G; Alman, Benjamin; Hawkins, Cynthia E; Malkin, David; Clifford, Steven C; Pfister, Stefan M; Taylor, Michael D; Tabori, Uri (BioMed Central, 2014)
      TP53 mutations confer subgroup specific poor survival for children with medulloblastoma. We hypothesized that WNT activation which is associated with improved survival for such children abrogates TP53 related radioresistance ...