Browsing HMS Scholarly Articles by Author "Kyung, Sun-Young"

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    • Circulating Mitochondrial DNA in Patients in the ICU as a Marker of Mortality: Derivation and Validation 

      Nakahira, Kiichi; Kyung, Sun-Young; Rogers, Angela J.; Gazourian, Lee; Youn, Sojung; Massaro, Anthony F.; Quintana, Carolina; Osorio, Juan C.; Wang, Zhaoxi; Zhao, Yang; Lawler, Laurie A.; Christie, Jason D.; Meyer, Nuala J.; Causland, Finnian R. Mc.; Waikar, Sushrut S.; Waxman, Aaron B.; Chung, Raymond T.; Bueno, Raphael; Rosas, Ivan O.; Fredenburgh, Laura E.; Baron, Rebecca M.; Christiani, David C.; Hunninghake, Gary M.; Choi, Augustine M. K. (Public Library of Science, 2013)
      Background: Mitochondrial DNA (mtDNA) is a critical activator of inflammation and the innate immune system. However, mtDNA level has not been tested for its role as a biomarker in the intensive care unit (ICU). We hypothesized ...