Browsing HMS Scholarly Articles by Harvard-affiliated Author "Hahn, William C."

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Browsing HMS Scholarly Articles by Harvard-affiliated Author

Browsing HMS Scholarly Articles by Harvard-affiliated Author "Hahn, William C."

Now showing items 1-20 of 25

Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

Chanock, Stephen J.; Schafer, Eric J.; Tabernero, Josep; Baselga, José; Oh, William K.; Pomerantz, Mark M; Shrestha, Yashaswi et al. (PLoS Genetics, 2010) Link to Published Version
The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis

Pomerantz, Mark M.; Li, Fugen; Takeda, David; Lenci, Romina; Chonkar, Apurva; Chabot, Matthew; Cejas, Paloma et al. (Nature genetics, 2015) Link to Published Version
BRAF Activation Initiates but Does Not Maintain Invasive Prostate Adenocarcinoma

Jeong, Joseph H.; Wang, Zhenxiong; Ouyang, Xuesong; Jiang, Shan; Guney, Isil; Kang, Gyeong Hoon; Abate-Shen, Cory et al. (PLoS ONE, 2008) Link to Published Version
BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

Abo, Ryan P.; Ducar, Matthew; Garcia, Elizabeth P.; Thorner, Aaron R.; Rojas-Rudilla, Vanesa; Lin, Ling; Sholl, Lynette M. et al. (Nucleic Acids Research, 2015) Link to Published Version
The Bromodomain Protein Brd4 Insulates Chromatin from DNA Damage Signaling

Floyd, Scott R.; Pacold, Michael E.; Huang, Qiuying; Clarke, Scott M.; Lam, Fred C.; Cannell, Ian G.; Bryson, Bryan D. et al. (Nature, 2013) Link to Published Version
CK1\(\varepsilon\) is Required for Breast Cancers Dependent on \(\beta\)-Catenin Activity

Firestein, Ron; Gupta, Piyush; Repich, Kara; Silver, Serena J.; Boehm, Jesse S.; Kim, So Young; Dunn, Ian Frederick et al. (PLoS ONE, 2010) Link to Published Version
Colorectal Cancers from Distinct Ancestral Populations Show Variations in BRAF Mutation Frequency

Hanna, Megan C.; Go, Christina; Roden, Christine; Jones, Robert T.; Pochanard, Panisa; Javed, Ahmed Yasir; Javed, Awais et al. (PLoS ONE, 2013) Link to Published Version
Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

Brastianos, Priscilla K.; Taylor-Weiner, Amaro; Manley, Peter E.; Jones, Robert T.; Dias-Santagata, Dora; Thorner, Aaron R.; Rodriguez, Fausto J. et al. (Nature genetics, 2014) Link to Published Version
Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development

Wiedemeyer, Ruprecht; Brennan, Cameron; Heffernan, Timothy P.; Xiao, Yonghong; Mahoney, John T.; Protopopov, Alexei; Zheng, Hongwu et al. (Cancer Cell, 2008) Link to Published Version
Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma

Hettmer, Simone; Schinzel, Anna C; Tchessalova, Daria; Schneider, Michaela; Parker, Christina L; Bronson, Roderick T; Richards, Nigel GJ et al. (eLife, 2015) Link to Published Version
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations

Brastianos, Priscilla K.; Horowitz, Peleg M.; Santagata, Sandro; Jones, Robert T.; McKenna, Aaron; Getz, Gad; Ligon, Keith L. et al. (Nature genetics, 2013) Link to Published Version
Integrated genetic and pharmacologic interrogation of rare cancers

Hong, Andrew L.; Tseng, Yuen-Yi; Cowley, Glenn S.; Jonas, Oliver; Cheah, Jaime H.; Kynnap, Bryan D.; Doshi, Mihir B. et al. (Nature Communications, 2016) Link to Published Version
Integrative functional genomics identifies RINT1 as a novel GBM oncogene

Quayle, Steven N.; Chheda, Milan G.; Shukla, Sachet A.; Wiedemeyer, Ruprecht; Tamayo, Pablo; Dewan, Robert W.; Zhuang, Li et al. (Neuro-Oncology, 2012) Link to Published Version
Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants

Chen, Tzu-Hsiu; Feng, Whei; Jänne, Pasi A; Alvarez, James V; Zappaterra, Mauro; Bulmer, Sara E; Sellers, William R et al. (PLoS Medicine, 2005) Link to Published Version
PAK1 is a Breast Cancer Oncogene that Coordinately Activates MAPK and MET Signaling

Shrestha, Yashaswi; Schafer, Eric J.; Boehm, Jesse S.; He, Frank; Wang, Shumei; Barretina, Jordi; Thomas, Sapana Rachael et al. (Oncogene, 2012) Link to Published Version
Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

Cowley, Glenn S; Weir, Barbara A; Vazquez, Francisca; Tamayo, Pablo; Scott, Justine A; Rusin, Scott; East-Seletsky, Alexandra et al. (Scientific Data, 2014) Link to Published Version
PRKACA Mediates Resistance to HER2-Targeted Therapy in Breast Cancer Cells and Restores Anti-Apoptotic Signaling

Moody, Susan E.; Schinzel, Anna C.; Singh, Shambhavi; Izzo, Francesca; Strickland, Matthew R.; Luo, Leo ; Thomas, Sapana R. et al. (Oncogene, 2014) Link to Published Version
Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

Campbell, Catarina D.; Kehoe, Sarah M.; Hatton, Charles; Niu, Lili; Yao, Keluo; Hanna, Megan; Mondal, Chandrani et al. (PLoS ONE, 2009) Link to Published Version
PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival

Iida, Naoko; Zou, Lihua; Yao, Jun; Lu, Yiling; Epstein, Charles B.; Natesan, Sridaran; Mills, Gordon B. et al. (PLoS ONE, 2010) Link to Published Version
The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

Firestein, Ron; Blander, Gil; Michan, Shaday; Oberdoerffer, Philipp; Luikenhuis, Sandra; de Cabo, Rafael; Guarente, Leonard P. et al. (PLoS ONE, 2008) Link to Published Version

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