Browsing HMS Scholarly Articles by Author "Xia, Fan"
Now showing items 1-4 of 4
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Diversity in Dermatology Clinical Trials
Charrow, Alexandra Phillippa; Xia, Fan; Joyce, Cara; Mostaghimi, Arash (American Medical Association (AMA), 2017)Question What is the racial, ethnic, and sex makeup of participants in randomized clinical trials of dermatologic conditions? Findings In this systematic review of 626 trials conducted in 2010 through 2015, there was ... -
Estimated Cost of Emergency Sunburn Visits—Validation of ICD-9-CM Search Criteria
Xia, Fan; Joyce, Cara; Mostaghimi, Arash (American Medical Association (AMA), 2017)To the Editor We applaud the evaluation by Guy and colleagues of costs for sunburn-associated visits to US emergency departments. Their analysis was performed using the International Classification of Diseases, Ninth ... -
The Mst1 and Mst2 kinases control activation of rho family GTPases and thymic egress of mature thymocytes
Mou, Fan; Praskova, Maria; Xia, Fan; Van Buren, Denille; Hock, Hanno Reinhard; Avruch, Joseph; Zhou, Dawang (The Rockefeller University Press, 2012)The Mst1 kinase is an important regulator of murine T cell adhesion, migration, proliferation, and apoptosis. In this study, we analyze mice lacking both Mst1 and Mst2 in hematopoietic cells. Compared with wild-type mice, ... -
Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene
Zhou, Dawang; Conrad, Claudius; Xia, Fan; Park, Ji-Sun; Payer, Bernhard; Yin, Yi; Lauwers, Gregory Y.; Thasler, Wolfgang; Lee, Jeannie T.; Avruch, Joseph; Bardeesy, Nabeel (Elsevier BV, 2009)Hippo-Lats-Yorkie signaling regulates tissue overgrowth and tumorigenesis in Drosophila. We show that the Mst1 and Mst2 protein kinases, the mammalian Hippo orthologs, are cleaved and constitutively activated in the mouse ...