Browsing HMS Scholarly Articles by Title
Now showing items 10428-10447 of 17922
-
A Method for Clustering White Matter Fiber Tracts
(American Society of Neuroradiology, 2006)BACKGROUND/PURPOSE: Despite its potential for visualizing white matter fiber tracts in vivo, diffusion tensor tractography has found only limited applications in clinical research in which specific anatomic connections ... -
Method for Combining Information from White Matter Fiber Tracking and Gray Matter Parcellation
(American Society of Neuroradiology, 2004)We introduce a method for combining fiber tracking from diffusion-tensor (DT) imaging with cortical gray matter parcellation from structural high-spatial-resolution 3D spoiled gradient-recalled acquisition in the steady ... -
A Method for High Throughput Determination of Viable Bacteria Cell Counts in 96-Well Plates
(BioMed Central, 2012)Background: There are several methods for quantitating bacterial cells, each with advantages and disadvantages. The most common method is bacterial plating, which has the advantage of allowing live cell assessment through ... -
A Method for High-Throughput Gene Expression Signature Analysis
(BioMed Central, 2006)Genome-wide transcriptional profiling has shown that different biologic states (for instance, disease and response to pharmacologic manipulation) can be recognized by the expression pattern of relatively small numbers of ... -
Method of Determining Nanoparticle Core Weight
(American Chemical Society, 2005)Polymer-coated metal or metal oxide nanoparticles have a variety of uses in industry, biological research, and medicine. Characterization of nanoparticles often includes determination of the dimensions of the electron-dense ... -
The Method of Randomization for Cluster-Randomized Trials: Challenges of Including Patients with Multiple Chronic Conditions
(2016)Cluster-randomized clinical trials (CRT) are trials in which the unit of randomization is not a participant but a group (e.g. healthcare systems or community centers). They are suitable when the intervention applies naturally ... -
A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases
(2016)There is growing evidence of shared risk alleles between complex traits (pleiotropy), including autoimmune and neuropsychiatric diseases. This might be due to sharing between all individuals (whole-group pleiotropy), or a ... -
Methodological challenges in identifying parenting behaviors as potential targets for intervention: Commentary on Stepp et al. (2011).
(American Psychological Association (APA), 2012)Comments on an article Children of mothers with borderline personality disorder: Identifying parenting behaviors as potential targets for intervention by Stepp, Whalen, Pilkonis, Hipwell, and Levine (see record 2011-05873-001). ... -
Methodological Framework for World Health Organization Estimates of the Global Burden of Foodborne Disease
(Public Library of Science, 2015)Background: The Foodborne Disease Burden Epidemiology Reference Group (FERG) was established in 2007 by the World Health Organization to estimate the global burden of foodborne diseases (FBDs). This paper describes the ... -
Methodology for developing quality indicators for the care of older people in the Emergency Department
(BioMed Central, 2013)Background: Compared with younger people, older people have a higher risk of adverse health outcomes when presenting to emergency departments. As the population ages, older people will make up an increasing proportion of ... -
Methodology for the Development of a Taxonomy and Toolkit to Evaluate Health-related Habits and Lifestyle (eVITAL)
(BioMed Central, 2010)Background: Chronic diseases cause an ever-increasing percentage of morbidity and mortality, but many have modifiable risk factors. Many behaviors that predispose or protect an individual to chronic disease are interrelated, ... -
Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization
(American Society for Microbiology, 1997-10)We have developed a new system of chromosomal mutagenesis in order to study the functions of uncharacterized open reading frames (ORFs) in wild-type Escherichia coli. Because of the operon structure of this organism, ... -
Methods of high integrity RNA extraction from cell/agarose construct
(BioMed Central, 2015)Background: Agarose hydrogels are widely used for three-dimensional cell scaffolding in tissue engineering and cell biology. Recently, molecular profiles have been obtained with extraction of a minimal volume of RNA using ... -
Methods of Suicide: International Suicide Patters Derived From the WHO Mortality Database
(World Health Organization, 2008-09)Objective Accurate information about preferred suicide methods is important for devising strategies and programmes for suicide prevention. Our knowledge of the methods used and their variation across countries and world ... -
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts
(Public Library of Science, 2015)Background: Typically, algorithms to classify phenotypes using electronic medical record (EMR) data were developed to perform well in a specific patient population. There is increasing interest in analyses which can allow ... -
Methylation by Set9 Modulates FoxO3 Stability and Transcriptional Activity
(Impact Journals LLC, 2012)The FoxO family of transcription factors plays an important role in longevity and tumor suppression by regulating the expression of a wide range of target genes. FoxO3 has recently been found to be associated with extreme ... -
Methylation-dependent and -independent roles of EZH2 synergize in CDCA8 activation in prostate cancer
(Springer Science and Business Media LLC, 2022-01-29)Cell division cycle associated 8 (CDCA8) is a component of chromosomal passenger complex (CPC) that participates in mitotic regulation. Although cancer-related CDCA8 hyperactivation has been widely observed, its molecular ... -
Methylene Chloride Poisoning in a Cabinet Worker
(National Institute of Environmental Health Sciences, 1999)More than a million workers are at risk for methylene chloride exposure. Aerosol sprays and paint stripping may also cause significant nonoccupational exposures. After methylene chloride inhalation, significant amounts of ... -
Methylmercury: significance of intrauterine and postnatal exposures.
(American Association for Clinical Chemistry, 1994)Outbreaks of methylmercury poisoning in Japan and Iraq have demonstrated the sensitivity of the fetus to neurotoxic effects. Based on toxicokinetics and considerations of practicability, the optimal biomarker of methylmercury ...