Browsing HMS Scholarly Articles by Title
Now showing items 11388-11407 of 17922
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Neural Tractography Using an Unscented Kalman Filter
(Springer Science + Business Media, 2009)We describe a technique to simultaneously estimate a local neural fiber model and trace out its path. Existing techniques estimate the local fiber orientation at each voxel independently so there is no running knowledge ... -
Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning
(Cold Spring Harbor Laboratory Press, 2012)In the vertebrate neural tube, regional Sonic hedgehog (Shh) signaling invokes a time-and concentration-dependent induction of six different cell populations mediated through Gli transcriptional regulators. Elsewhere in ... -
Neurally adjusted ventilatory assist in patients with acute respiratory failure: study protocol for a randomized controlled trial
(BioMed Central, 2016)Background: Patient-ventilator asynchrony is a common problem in mechanically ventilated patients with acute respiratory failure. It is assumed that asynchronies worsen lung function and prolong the duration of mechanical ... -
A neuraminidase from Trypanosoma cruzi removes sialic acid from the surface of mammalian myocardial and endothelial cells
(American Society for Clinical Investigation, 1986)Trypanosoma cruzi causes Chagasic heart disease, a major public health problem in Latin America. The mechanism of interaction of this protozooan parasite with host cells is poorly understood. We recently found that the ... -
Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth
(Public Library of Science, 2016)Background: We previously developed and validated a strategy for stimulating heart regeneration by administration of recombinant neuregulin (rNRG1), a growth factor, in mice. rNRG1 stimulated proliferation of heart muscle ... -
Neuregulin1-β Decreases IL-1β -Induced Neutrophil Adhesion to Human Brain Microvascular Endothelial Cells
(Springer Nature, 2014)Neuroinflammation contributes to the pathophysiology of diverse diseases including stroke, traumatic brain injury, Alzheimer's Disease, Parkinson's Disease, and multiple sclerosis, resulting in neurodegeneration and loss ... -
Neurite outgrowth induced by an endothelial cell mitogen isolated from retina
(Rockefeller University Press, 1986)Retina-derived growth factor (RDGF) is a polypeptide growth factor purified from salt extracts of bovine retinas on the basis of its mitogenic activity for capillary endothelial cells (EC) and BALB/c 3T3 cells. RDGF is ... -
Neuro-Epigenetic Indications of Acute Stress Response in Humans: The Case of MicroRNA-29c
(Public Library of Science, 2016)Stress research has progressively become more integrative in nature, seeking to unfold crucial relations between the different phenotypic levels of stress manifestations. This study sought to unravel stress-induced variations ... -
Neuroaesthetics and the Trouble with Beauty
(Public Library of Science, 2013)Neuroscience is increasingly being called upon to address issues within the humanities. We discuss challenges that arise, relating to art and beauty, and provide ideas for a way forward. -
Neuroanatomy goes viral!
(Frontiers Media S.A., 2015)The nervous system is complex not simply because of the enormous number of neurons it contains but by virtue of the specificity with which they are connected. Unraveling this specificity is the task of neuroanatomy. In ... -
Neurobehavioral Deficits and Increased Blood Pressure in School-Age Children Prenatally Exposed to Pesticides
(National Institute of Environmental Health Sciences, 2010)Background: The long-term neurotoxicity risks caused by prenatal exposures to pesticides are unclear, but a previous pilot study of Ecuadorian school children suggested that blood pressure and visuospatial processing may ... -
Neurobehavioral Function in School-Age Children Exposed to Manganese in Drinking Water
(NLM-Export, 2014)Background: Manganese neurotoxicity is well documented in individuals occupationally exposed to airborne particulates, but few data are available on risks from drinking-water exposure. Objective: We examined associations ... -
A Neurobehavioral Intervention Incorporated into a State Early Intervention Program is Associated with Higher Perceived Quality of Care Among Parents of High-Risk Newborns
(Springer Nature, 2012)The purpose of this study is to compare two models of early intervention (EI) service delivery—a neurobehavioral intervention and usual care—on parents' perceived quality of EI service delivery. Families of newborns referred ... -
Neurobiological basis of head motion in brain imaging
(National Academy of Sciences, 2014)Individual differences in brain metrics, especially connectivity measured with functional MRI, can correlate with differences in motion during data collection. The assumption has been that motion causes artifactual differences ... -
Neurobiological Effects of Transcranial Direct Current Stimulation: A Review
(Frontiers Media S.A., 2012)Transcranial Direct Current Stimulation (tDCS) is a non-invasive brain stimulation technique that is affordable and easy to operate compared to other neuromodulation techniques. Anodal stimulation increases cortical ... -
Neurobiological Indicators of Disinhibition in Posttraumatic Stress Disorder
(Wiley, 2015-08)Deficits in impulse control are increasingly recognized in association with posttraumatic stress disorder (PTSD). To our further understanding of the neurobiology of PTSD‐related disinhibition, we examined alterations in ... -
Neurobiological underpinnings of reward anticipation and outcome evaluation in gambling disorder
(Frontiers Media S.A., 2014)Gambling disorder is characterized by persistent and recurrent maladaptive gambling behavior, which leads to clinically significant impairment or distress. The disorder is associated with dysfunctions in the dopamine system. ... -
The Neurobiology Shaping Affective Touch: Expectation, Motivation, and Meaning in the Multisensory Context
(Frontiers Media S.A., 2016)Inter-individual touch can be a desirable reward that can both relieve negative affect and evoke strong feelings of pleasure. However, if other sensory cues indicate it is undesirable to interact with the toucher, the ... -
Neuroblast Distribution after Cortical Impact Is Influenced by White Matter Injury in the Immature Gyrencephalic Brain
(Frontiers Media S.A., 2016)Cortical contusions are a common type of traumatic brain injury (TBI) in children. Current knowledge of neuroblast response to cortical injury arises primarily from studies utilizing aspiration or cryoinjury in rodents. ... -
Neurochemical changes in patients with chronic low back pain detected by proton magnetic resonance spectroscopy: A systematic review
(Elsevier, 2016)Background: Low back pain is a highly prevalent health problem around the world, affecting 50% to 85% of people at some point in life. The purpose of this systematic review is to summarize the previous proton magnetic ...