Now showing items 1225-1244 of 17918

    • Association of Dermatologist Density With the Volume and Costs of Dermatology Procedures Among Medicare Beneficiaries 

      Tan, Sally; Tsoucas, Daphne Maria; Mostaghimi, Arash (American Medical Association (AMA), 2018)
      Importance The persistent shortage of dermatologists in the United States affects access to care and patient outcomes. Objective To characterize the effect of geographic variations in dermatologist density on the ...
    • Association of Dietary Nitrate Intake With Primary Open-Angle Glaucoma 

      Kang, Jae Hee; Willett, Walter C.; Rosner, Bernard Alfred; Buys, Emmanuel; Wiggs, Janey Lee; Pasquale, Louis (American Medical Association (AMA), 2016)
      IMPORTANCE Nitric oxide signaling alterations in outflow facility and retinal blood flow autoregulation are implicated in primary open-angle glaucoma (POAG). Nitric oxide donation has emerged as a POAG therapeutic target. ...
    • The Association of Early Childhood Cognitive Development and Behavioural Difficulties with Pre-Adolescent Problematic Eating Attitudes 

      Richmond, Rebecca C.; Skugarevsky, Oleg; Yang, Seungmi; Kramer, Michael S.; Wade, Kaitlin H.; Patel, Rita; Bogdanovich, Natalia; Vilchuck, Konstantin; Sergeichick, Natalia; Smith, George Davey; Oken, Emily; Martin, Richard M. (Public Library of Science, 2014)
      Objectives: Few studies have prospectively investigated associations of child cognitive ability and behavioural difficulties with later eating attitudes. We investigated associations of intelligence quotient (IQ), academic ...
    • Association of Environmental Cadmium Exposure with Pediatric Dental Caries 

      Arora, Manish; Weuve, Jennifer Lynn; Schwartz, Joel David; Wright, Robert O. (National Institute of Environmental Health Sciences, 2008)
      Background: Although animal experiments have shown that cadmium exposure results in severe dental caries, limited epidemiologic data are available on this issue. Objectives: We aimed to examine the relationship between ...
    • Association of Environmental Cadmium Exposure with Periodontal Disease in U.S. Adults 

      Arora, Manish; Weuve, Jennifer Lynn; Schwartz, Joel David; Wright, Robert O. (National Institute of Environmental Health Sciences, 2009)
      Background: Periodontal disease is a complex, multifactorial, chronic inflammatory disease that involves degradation of periodontal structures, including alveolar bone. Cadmium adversely affects bone remodeling, and it is ...
    • Association of Estimated Glomerular Filtration Rate and Urinary Uromodulin Concentrations with Rare Variants Identified by UMOD Gene Region Sequencing 

      Köttgen, Anna; Yang, Qiong; Shimmin, Lawrence C.; Tin, Adrienne; Schaeffer, Céline; Coresh, Josef; Liu, Xuan; Rampoldi, Luca; Hwang, Shih-Jen; Boerwinkle, Eric; Hixson, James E.; Kao, W.H. Linda; Fox, Caroline (Public Library of Science, 2012)
      Background: Recent genome-wide association studies (GWAS) have identified common variants in the UMOD region associated with kidney function and disease in the general population. To identify novel rare variants as well ...
    • The Association of Ethnic Minority Density with Late Entry into Antenatal Care in the Netherlands 

      Posthumus, Anke G.; Schölmerich, Vera L. N.; Steegers, Eric A. P.; Kawachi, Ichiro; Denktaş, Semiha (Public Library of Science, 2015)
      In the Netherlands, non-Western ethnic minority women make their first antenatal visit later than native Dutch women. Timely entry into antenatal care is important as it provides the opportunity for prenatal screening and ...
    • Association of Expired Nitric Oxide with Occupational Particulate Exposure 

      Kim, Jee Young; Wand, Matthew P; Hauser, Russ B.; Mukherjee, Sutapa; Herrick, Robert F.; Christiani, David C. (2003)
      Particulate air pollution has been associated with adverse respiratory health effects. This study assessed the utility of expired nitric oxide to detect acute airway responses to metal-containing fine particulates. Using ...
    • Association of Exposure to Phthalates with Endometriosis and Uterine Leiomyomata: Findings from NHANES, 1999–2004 

      Weuve, Jennifer Lynn; Hauser, Russ B.; Calafat, Antonia M.; Missmer, Stacey Ann; Wise, Lauren A. (National Institute of Environmental Health Sciences, 2010)
      Background: Phthalates are ubiquitous chemicals used in consumer products. Some phthalates are reproductive toxicants in experimental animals, but human data are limited. Objective: We conducted a cross-sectional study of ...
    • Association of Fat Density With Subclinical Atherosclerosis 

      Alvey, Nicholas J.; Pedley, Alison; Rosenquist, Klara J.; Massaro, Joseph M.; O'Donnell, Christopher J.; Hoffmann, Udo; Fox, Caroline S. (Blackwell Publishing Ltd, 2014)
      Background: Ectopic fat density is associated with cardiovascular disease (CVD) risk factors above and beyond fat volume. Volumetric measures of ectopic fat have been associated with CVD risk factors and subclinical ...
    • Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis 

      Mitsuhashi, Kei; Nosho, Katsuhiko; Sukawa, Yasutaka; Matsunaga, Yasutaka; Ito, Miki; Kurihara, Hiroyoshi; Kanno, Shinichi; Igarashi, Hisayoshi; Naito, Takafumi; Adachi, Yasushi; Tachibana, Mami; Tanuma, Tokuma; Maguchi, Hiroyuki; Shinohara, Toshiya; Hasegawa, Tadashi; Imamura, Masafumi; Kimura, Yasutoshi; Hirata, Koichi; Maruyama, Reo; Suzuki, Hiromu; Imai, Kohzoh; Yamamoto, Hiroyuki; Shinomura, Yasuhisa (Impact Journals LLC, 2015)
      Recently, bacterial infection causing periodontal disease has attracted considerable attention as a risk factor for pancreatic cancer. Fusobacterium species is an oral bacterial group of the human microbiome. Some evidence ...
    • Association of Genes, Pathways, and Haplogroups of the Mitochondrial Genome with the Risk of Colorectal Cancer: The Multiethnic Cohort 

      Li, Yuqing; Beckman, Kenneth B.; Caberto, Christian; Kazma, Remi; Lum-Jones, Annette; Haiman, Christopher A.; Marchand, Loïc Le; Stram, Daniel O.; Saxena, Richa; Cheng, Iona (Public Library of Science, 2015)
      The mitochondrial genome encodes for the synthesis of 13 proteins that are essential for the oxidative phosphorylation (OXPHOS) system. Inherited variation in mitochondrial genes may influence cancer development through ...
    • Association of Genetic Variants of Melatonin Receptor 1B with Gestational Plasma Glucose Level and Risk of Glucose Intolerance in Pregnant Chinese Women 

      Liao, Shunyao; Liu, Yunqiang; Tan, Yuande; Gan, Lu; Mei, Jie; Song, Wenzhong; Chi, Shu; Dong, Xianjue; Chen, Xiaojuan; Deng, Shaoping (Public Library of Science, 2012)
      Background: This study aimed to explore the association of MTNR1B genetic variants with gestational plasma glucose homeostasis in pregnant Chinese women. Methods: A total of 1,985 pregnant Han Chinese women were recruited ...
    • Association of Genetic Variation in \(FTO\) with Risk of Obesity and Type 2 Diabetes with Data from 96,551 East and South Asians 

      Kilpeläinen, T. O.; Sekine, A.; Yajnik, C. S.; Takeuchi, F.; Yamamoto, K.; Mani, K. R.; Been, L. F.; Imamura, M.; Nakashima, E.; Fujisawa, T.; Karasawa, S.; Joglekar, C. V.; Fall, C. H. D.; Sham, P. C.; Shu, X.; Deng, H.; Ikegami, H.; Krishnaveni, G. V.; Sanghera, D. K.; Chuang, L.; Daimon, M.; Hotta, K.; Kooner, J. S.; Chandak, G. R.; Maeda, S.; Dorajoo, R.; Yokota, M.; Takayanagi, R.; Loos, R. J. F.; Song, Yiqing; Li, H.; Liu, C.; Zhu, J.; Liu, Y.; Hu, C.; Yang, Z.; Zhang, W.; Bao, W.; Cha, S.; Wu, Y.; Yang, T.; Choi, B. Y.; Zhou, D.; Chan, J. C.; Lee, N.; Wen, W.; Lu, W.; Chang, Y.; Xiang, Y.; Gao, Y.; Liu, S.; Song, Yiqing; Kwak, S. H.; Shin, H. D.; Park, K. S.; Kim, J. Y.; Lam, K. S. L.; Zheng, W.; Liu, L.; Hu, R.; Kim, Y.; Jia, W.; Chambers, J. C.; Ma, R. C.; Kato, N.; Lin, X. (Springer-Verlag, 2012)
      Aims/hypothesis: \(FTO\) harbours the strongest known obesity-susceptibility locus in Europeans. While there is growing evidence for a role for \(FTO\) in obesity risk in Asians, its association with type 2 diabetes, ...
    • The association of GPR85 with PSD-95-neuroligin complex and autism spectrum disorder: a molecular analysis 

      Fujita-Jimbo, Eriko; Tanabe, Yuko; Yu, Zhiling; Kojima, Karin; Mori, Masato; Li, Hong; Iwamoto, Sadahiko; Yamagata, Takanori; Momoi, Mariko Y; Momoi, Takashi (BioMed Central, 2015)
      Background: Autism spectrum disorder (ASD) has a complex genetic etiology. Some symptoms and mutated genes, including neuroligin (NLGN), neurexin (NRXN), and SH3 and multiple ankyrin repeat domains protein (SHANK), are ...
    • Association of Hexachlorobenzene (HCB), Dichlorodiphenyltrichloroethane (DDT), and Dichlorodiphenyldichloroethylene (DDE) with in Vitro Fertilization (IVF) Outcomes 

      Mahalingaiah, Shruthi; Maity, Arnab; Meeker, John D.; Berry, Katharine; Missmer, Stacey Ann; Williams, Paige L.; Ehrlich, Shelley; Perry, Melissa J.; Cramer, Daniel William; Hauser, Russ B. (National Institute of Environmental Health Sciences, 2012)
      Background: Hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) are persistent chlorinated pesticides with endocrine activity that may adversely affect the early stages ...
    • Association of HLA-DRB1-restricted CD4+ T cell responses with HIV immune control 

      Ranasinghe, Srinika; Cutler, Sam; Davis, Isaiah; Lu, Richard; Soghoian, Damien Z.; Qi, Ying; Sidney, John; Kranias, Gregory; Flanders, Michael; Lindqvist, Madelene; Kuhl, Bjorn; Alter, Galit; Deeks, Steven G.; Walker, Bruce D.; Gao, Xiaojiang; Sette, Alessandro; Carrington, Mary; Streeck, Hendrik (2013)
      The contribution of HLA class II-restricted CD4+ T cell responses to HIV immune control is poorly defined. Here, we delineated novel peptide-DRB1 restrictions in functional assays and analyzed the host genetic effects of ...
    • Association of Incident Cardiovascular Disease With Progression of Sleep-Disordered Breathing 

      Chami, Hassan; Resnick, Helaine; Quan, Stuart; Gottlieb, Daniel (Ovid Technologies (Wolters Kluwer Health), 2011-03-29)
      Background—Prospective data suggest that sleep-disordered breathing enhances risk for incident and recurrent cardiovascular disease (CVD). However, a reverse causal pathway whereby incident CVD causes or worsens sleep-disordered ...
    • Association of IREB2 and CHRNA3 Polymorphisms with Airflow Obstruction in Severe Alpha-1 Antitrypsin Deficiency 

      Wood, Alice M; Barker, Alan F; Brantly, Mark L; Campbell, Edward J; Eden, Edward; McElvaney, Gerard; Rennard, Stephen I; Sandhaus, Robert A; Stocks, James M; Stoller, James K; Strange, Charlie; Turino, Gerard; Stockley, Robert A; Silverman, Edwin Kepner; Demeo, Dawn Lisa; Kim, Woo Jin (BioMed Central, 2012)
      Background: The development of COPD in subjects with alpha-1 antitrypsin (AAT) deficiency is likely to be influenced by modifier genes. Genome-wide association studies and integrative genomics approaches in COPD have ...
    • Association of Left Ventricular Hypertrophy With a Faster Rate of Renal Function Decline in Elderly Patients With Non‐End‐Stage Renal Disease 

      Shi, Hong‐tao; Wang, Xiao‐jing; Li, Jun; Song, Gui‐fang; Huang, Zhe‐yong; Guo, Xiang‐yu; Guo, Jun‐jie; Lv, Zhi‐yang; Li, Hong‐wei; Ge, Jun‐bo; Cui, Jie; Qi, Guan‐ming (John Wiley and Sons Inc., 2015)
      Background: Several studies have indicated that chronic kidney disease is independently associated with the presence of left ventricular hypertrophy (LVH). However, little clinical data are currently available regarding ...