Browsing HMS Scholarly Articles by Title

Now showing items 1264-1283 of 17920

    • The association of plasma biomarkers with computed tomography-assessed emphysema phenotypes 

      Carolan, Brendan J; Hughes, Grant; Morrow, Jarrett; Hersh, Craig P; O’Neal, Wanda K; Rennard, Stephen; Pillai, Sreekumar G; Belloni, Paula; Cockayne, Debra A; Comellas, Alejandro P; Han, Meilan; Zemans, Rachel L; Kechris, Katerina; Bowler, Russell P (BioMed Central, 2014)
      Rationale: Chronic obstructive pulmonary disease (COPD) is a phenotypically heterogeneous disease. In COPD, the presence of emphysema is associated with increased mortality and risk of lung cancer. High resolution computed ...

    • Association of Plasma Phospholipid Long-Chain Omega-3 Fatty Acids With Incident Atrial Fibrillation in Older Adults: The Cardiovascular Health Study 

      Wu, J. H. Y.; Lemaitre, R. N.; King, I. B.; Song, X.; Sacks, Frank Martin; Rimm, Eric Bruce; Heckbert, S. R.; Siscovick, D. S.; Mozaffarian, D (Ovid Technologies (Wolters Kluwer Health), 2012)
      BACKGROUND: Experimental studies suggest that long-chain n-3 polyunsaturated fatty acids (n-3 PUFAs) may reduce the risk of atrial fibrillation (AF). Prior studies evaluating fish or n-3 PUFA consumption from dietary ...

    • Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1 

      Howitt, Brooke Elizabeth; Shukla, Sachet; Sholl, Lynette Marie; Ritterhouse, Lauren Lee; Watkins, Jaclyn Christine; Rodig, Scott J.; Stover, Elizabeth Harmon; Strickland, Kyle Craig; D'Andrea, Alan David; Wu, Catherine Ju-Ying; Matulonis, Ursula Anne; Konstantinopoulos, Panagiotis (American Medical Association (AMA), 2015)
      Importance Immune checkpoint inhibitor therapy has shown benefit in various cancers, but their potential in endometrial cancer (EC) is unknown. Observations Prediction of neoantigen load was performed using sequencing ...

    • Association of Prenatal Exposure to Persistent Organic Pollutants with Obesity and Cardiometabolic Traits in Early Childhood: The Rhea Mother–Child Cohort (Crete, Greece) 

      Vafeiadi, Marina; Georgiou, Vaggelis; Chalkiadaki, Georgia; Rantakokko, Panu; Kiviranta, Hannu; Karachaliou, Marianna; Fthenou, Eleni; Venihaki, Maria; Sarri, Katerina; Vassilaki, Maria; Kyrtopoulos, Soterios A.; Oken, Emily; Kogevinas, Manolis; Chatzi, Leda (NLM-Export, 2015)
      Background: Prenatal exposure to endocrine-disrupting chemicals such as persistent organic pollutants (POPs) may increase risk of obesity later in life. Objective: We examined the relation of in utero POPs exposure to ...

    • Association of probable post-traumatic stress disorder with dietary pattern and gut microbiome in a cohort of women 

      Ke, Shanlin; Wang, Xu-Wen; Ratanatharathorn, Andrew; Huang, Tianyi; Roberts, Andrea L.; Grodstein, Francine; Kubzansky, Laura D.; Koenen, Karestan C.; Liu, Yang-Yu (Springer Science and Business Media LLC, 2023-10-19)
      Post-Traumatic Stress Disorder (PTSD) is a psychiatric condition that may occur in people who have experienced or witnessed traumatic or horrifying events. PTSD has been linked to an increased risk of various chronic ...

    • Association of Race/Ethnicity with Emergency Department Wait Times 

      Bourgeois, Florence; James, Catherine; Shannon, Michael (American Academy of Pediatrics (AAP), 2005)
      OBJECTIVE:To determine whether wait times for children treated in emergency departments (EDs) nationally are associated with patient race/ethnicity. METHODS:Data were obtained from the National Hospital Ambulatory Medical ...

    • Association of Regional Variation in Primary Care Physicians’ Colorectal Cancer Screening Recommendations with Individual Use of Colorectal Cancer Screening 

      Haas, Jennifer S.; Fitzmaurice, Garrett M.; Brawarsky, Phyllis; Liang, Su-Ying; Hiatt, Robert A; Phillips, Kathryn A; Klabunde, Carrie N; Brown, Martin L (Centers for Disease Control and Prevention, 2007)
      Introduction: Studies show that the recommendations of a primary care physician for colorectal cancer screening may be one important influence on an individual's use of screening. However, another possible influence, the ...

    • Association of Sleep Disorders With Physician Burnout 

      Weaver, Matthew; Robbins, Rebecca; Quan, Stuart; O’Brien, Conor S.; Viyaran, Natalie; Czeisler, Charles; Barger, Laura K.; Barger, Laura (American Medical Association (AMA), 2020-10-30)
      Physicians’ mental health concerns affect the quality of life of caregivers, patient safety, health care expenditures, and occupational turnover. More than half of US physicians report burnout. Sleep deficiency is common—often ...

    • Association of sports drinks with weight gain among adolescents and young adults 

      Field, Alison E.; Sonneville, Kendrin R.; Falbe, Jennifer; Flint, Alan; Haines, Jess; Rosner, Bernard; Camargo, Carlos A. (2014)
      Objective: Sales of regular soda are declining, but sales of other sweetened beverages, such as sports drinks, are increasing. Our objective was to determine the prospective associations between sports drinks and body mass ...

    • Association of Statins with Sensory and Autonomic Ganglionopathy 

      Novak, Peter; Pimentel, Daniela A.; Sundar, Banu; Moonis, Majaz; Qin, Lan; Novak, Vera (Frontiers Media S.A., 2015)
      Objective: To examine if statins have an effect on small nerve fibers. Methods: This retrospective study evaluated the effect of statins in pure small-fiber neuropathy (SFN). Outcome measures were symptom scales (numbness, ...

    • The Association of Systemic Microvascular Changes with Lung Function and Lung Density: A Cross-Sectional Study 

      Harris, Bianca; Klein, Ronald; Jerosch-Herold, Michael; Hoffman, Eric A.; Ahmed, Firas S.; Klein, Barbara E. K.; Wong, Tien Y.; Lima, Joao A. C.; Cotch, Mary Frances; Barr, R. Graham; Jacobs, David R., Jr. (Public Library of Science, 2012)
      Smoking causes endothelial dysfunction and systemic microvascular disease with resultant end-organ damage in the kidneys, eyes and heart. Little is known about microvascular changes in smoking-related lung disease. We ...

    • Association of the blood/air partition coefficient of 1,3-butadiene with blood lipids and albumin. 

      Lin, Yu-Sheng; Smith, Thomas; Kelsey, Karl; Sacks, Frank Martin (National Institute of Environmental Health Sciences, 2017-02-07)
      Pulmonary gas uptake is a function of the blood solubility of a vapor, indicated by the blood/air partition coefficient. We hypothesized that blood lipid compositions are associated with the blood/air partition coefficients ...

    • Association of Urinary Concentrations of Bisphenol A and Phthalate Metabolites with Risk of Type 2 Diabetes: A Prospective Investigation in the Nurses’ Health Study (NHS) and NHSII Cohorts 

      Sun, Qi; Cornelis, Marilyn C.; Townsend, Mary K.; Tobias, Deirdre K.; Eliassen, A. Heather; Franke, Adrian A.; Hauser, Russ; Hu, Frank B. (NLM-Export, 2014)
      Background: Prospective evidence regarding associations for exposures to bisphenol A (BPA) and phthalates with type 2 diabetes (T2D) is lacking. Objective: We prospectively examined urinary concentrations of BPA and phthalate ...

    • Association of Variants in RETN with Plasma Resistin Levels and Diabetes-Related Traits in the Framingham Offspring Study 

      Hivert, Marie-France; Manning, Alisa K.; McAteer, Jarred B.; Dupuis, Josée; Fox, Caroline; Cupples, L. Adrienne; Meigs, James Benjamin; Florez, Jose Carlos (American Diabetes Association, 2009)
      OBJECTIVE— The RETN gene encodes the adipokine resistin. Associations of RETN with plasma resistin levels, type 2 diabetes, and related metabolic traits have been inconsistent. Using comprehensive linkage disequilibrium ...

    • Association of Vitamin D Status and Acute Rhinosinusitis: Results From the United States National Health and Nutrition Examination Survey 2001–2006 

      Khalid, Ayesha N.; Ladha, Karim S.; Luong, Amber U.; Quraishi, Sadeq A. (Wolters Kluwer Health, 2015)
      Abstract Although vitamin D status may be a modifiable risk factor for various respiratory ailments, limited data exists regarding its role in sinonasal infections. Our goal was to investigate the association of 25-hydroxyvitamin ...

    • Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study 

      Vimaleswaran, Karani S; Cavadino, Alana; Berry, Diane J; Jorde, Rolf; Dieffenbach, Aida Karina; Lu, Chen; Alves, Alexessander Couto; Heerspink, Hiddo J Lambers; Tikkanen, Emmi; Eriksson, Joel; Wong, Andrew; Mangino, Massimo; Jablonski, Kathleen A; Nolte, Ilja M; Houston, Denise K; Ahluwalia, Tarunveer Singh; van der Most, Peter J; Pasko, Dorota; Zgaga, Lina; Thiering, Elisabeth; Vitart, Veronique; Fraser, Ross M; Huffman, Jennifer E; de Boer, Rudolf A; Schöttker, Ben; Saum, Kai-Uwe; McCarthy, Mark I; Dupuis, Josée; Herzig, Karl-Heinz; Sebert, Sylvain; Pouta, Anneli; Laitinen, Jaana; Kleber, Marcus E; Navis, Gerjan; Lorentzon, Mattias; Jameson, Karen; Arden, Nigel; Cooper, Jackie A; Acharya, Jayshree; Hardy, Rebecca; Raitakari, Olli; Ripatti, Samuli; Billings, Liana K; Lahti, Jari; Osmond, Clive; Penninx, Brenda W; Rejnmark, Lars; Lohman, Kurt K; Paternoster, Lavinia; Stolk, Ronald P; Hernandez, Dena G; Byberg, Liisa; Hagström, Emil; Melhus, Håkan; Ingelsson, Erik; Mellström, Dan; Ljunggren, Östen; Tzoulaki, Ioanna; McLachlan, Stela; Theodoratou, Evropi; Tiesler, Carla M T; Jula, Antti; Navarro, Pau; Wright, Alan F; Polasek, Ozren; Hayward, Caroline; Wilson, James F; Rudan, Igor; Salomaa, Veikko; Heinrich, Joachim; Campbell, Harry; Price, Jacqueline F; Karlsson, Magnus; Lind, Lars; Michaëlsson, Karl; Bandinelli, Stefania; Frayling, Timothy M; Hartman, Catharina A; Sørensen, Thorkild I A; Kritchevsky, Stephen B; Langdahl, Bente Lomholt; Eriksson, Johan G; Florez, Jose C; Spector, Tim D; Lehtimäki, Terho; Kuh, Diana; Humphries, Steve E; Cooper, Cyrus; Ohlsson, Claes; März, Winfried; de Borst, Martin H; Kumari, Meena; Kivimaki, Mika; Wang, Thomas J; Power, Chris; Brenner, Hermann; Grimnes, Guri; van der Harst, Pim; Snieder, Harold; Hingorani, Aroon D; Pilz, Stefan; Whittaker, John C; Järvelin, Marjo-Riitta; Hyppönen, Elina (2015)
      Summary Background: Low plasma 25-hydroxyvitamin D (25[OH]D) concentration is associated with high arterial blood pressure and hypertension risk, but whether this association is causal is unknown. We used a mendelian ...

    • Association Study between the FTCDNL1 (FONG) and Susceptibility to Osteoporosis 

      Lu, Hsing-Fang; Hung, Kuo-Sheng; Hsu, Yu-Wen; Tai, Yu-Ting; Huang, Lin-Shan; Wang, Yu-Jia; Wong, Henry Sung-Ching; Hsu, Yi-Hsiang; Chang, Wei-Chiao (Public Library of Science, 2015)
      Osteoporosis is a systemic skeletal disease characterized by a decreased bone mineral density that results in an increased risk of fragility fractures. Previous studies indicated that genetic factors are involved in the ...

    • Association Study of 167 Candidate Genes for Schizophrenia Selected by a Multi-Domain Evidence-Based Prioritization Algorithm and Neurodevelopmental Hypothesis 

      Zhao, Zhongming; Webb, Bradley T.; Jia, Peilin; Bigdeli, T. Bernard; Maher, Brion S.; van den Oord, Edwin; Bergen, Sarah E.; Amdur, Richard L.; O'Neill, Francis A.; Walsh, Dermot; Thiselton, Dawn L.; Chen, Xiangning; Pato, Carlos N.; Riley, Brien P.; Kendler, Kenneth S.; Fanous, Ayman H. (Public Library of Science, 2013)
      Integrating evidence from multiple domains is useful in prioritizing disease candidate genes for subsequent testing. We ranked all known human genes (n = 3819) under linkage peaks in the Irish Study of High-Density ...

    • Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls 

      McLaren, Paul J.; Coulonges, Cédric; Ripke, Stephan; van den Berg, Leonard; Buchbinder, Susan; Carrington, Mary; Cossarizza, Andrea; Dalmau, Judith; Deeks, Steven G.; Delaneau, Olivier; De Luca, Andrea; Goedert, James J.; Haas, David; Herbeck, Joshua T.; Kathiresan, Sekar; Kirk, Gregory D.; Lambotte, Olivier; Luo, Ma; Mallal, Simon; van Manen, Daniëlle; Martinez-Picado, Javier; Meyer, Laurence; Miro, José M.; Mullins, James I.; Obel, Niels; O'Brien, Stephen J.; Pereyra, Florencia; Plummer, Francis A.; Poli, Guido; Qi, Ying; Rucart, Pierre; Sandhu, Manj S.; Shea, Patrick R.; Schuitemaker, Hanneke; Theodorou, Ioannis; Vannberg, Fredrik; Veldink, Jan; Walker, Bruce D.; Weintrob, Amy; Winkler, Cheryl A.; Wolinsky, Steven; Telenti, Amalio; Goldstein, David B.; de Bakker, Paul I. W.; Zagury, Jean-François; Fellay, Jacques (Public Library of Science, 2013)
      Multiple genome-wide association studies (GWAS) have been performed in HIV-1 infected individuals, identifying common genetic influences on viral control and disease course. Similarly, common genetic correlates of acquisition ...

    • Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy 

      Williams, Winfred W.; Salem, Rany M.; McKnight, Amy Jayne; Sandholm, Niina; Forsblom, Carol; Taylor, Andrew; Guiducci, Candace; McAteer, Jarred B.; McKay, Gareth J.; Isakova, Tamara; Brennan, Eoin P.; Sadlier, Denise M.; Palmer, Cameron; Söderlund, Jenny; Fagerholm, Emma; Harjutsalo, Valma; Lithovius, Raija; Gordin, Daniel; Hietala, Kustaa; Kytö, Janne; Parkkonen, Maija; Rosengård-Bärlund, Milla; Thorn, Lena; Syreeni, Anna; Tolonen, Nina; Saraheimo, Markku; Wadén, Johan; Pitkäniemi, Janne; Sarti, Cinzia; Tuomilehto, Jaakko; Tryggvason, Karl; Österholm, Anne-May; He, Bing; Bain, Steve; Martin, Finian; Godson, Catherine; Hirschhorn, Joel N.; Maxwell, Alexander P.; Groop, Per-Henrik; Florez, Jose C. (American Diabetes Association, 2012)
      We formed the GEnetics of Nephropathy–an International Effort (GENIE) consortium to examine previously reported genetic associations with diabetic nephropathy (DN) in type 1 diabetes. GENIE consists of 6,366 similarly ...