Browsing HMS Scholarly Articles by Title
Now showing items 12983-13002 of 17922
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Postmarket Surveillance of Medical Devices: A Comparison of Strategies in the US, EU, Japan, and China
(Public Library of Science, 2013)Daniel Kramer and colleagues compare strategies for postmarket surveillance of medical devices and discuss ways to improve these systems. Please see later in the article for the Editors' Summary -
Postmarketing Trials and Pediatric Device Approvals
(American Academy of Pediatrics (AAP), 2014)BACKGROUND: Medical devices can be useful in a variety of diseases, but few devices have been specifically approved for use in children. The 2007 Pediatric Medical Device Safety and Improvement Act was passed to stimulate ... -
Postmenopausal Estrogen and Progestin Effects on the Serum Proteome
(BioMed Central, 2009)Background: Women's Health Initiative randomized trials of postmenopausal hormone therapy reported intervention effects on several clinical outcomes, with some important differences between estrogen alone and estrogen plus ... -
Postmenopausal hormone therapy and the risk of rheumatoid arthritis: results from the Swedish EIRA population-based case-control study
(Springer Netherlands, 2015)To study the association between postmenopausal hormone therapy (PMH) use and the risk of rheumatoid arthritis (RA) stratifying the cases by the presence/absence of antibodies against citrullinated peptides (ACPA). A subset ... -
Postmenopausal mammographic breast density and subsequent breast cancer risk according to selected tissue markers
(Nature Publishing Group, 2015)Background: This study aimed to determine if associations of pre-diagnostic percent breast density, absolute dense area, and non-dense area with subsequent breast cancer risk differ by the tumour's molecular marker status. ... -
Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction
(Nature Pub. Group, 2014)Modern scientific knowledge of how memory functions are organized in the human brain originated from the case of Henry G. Molaison (H.M.), an epileptic patient whose amnesia ensued unexpectedly following a bilateral surgical ... -
Postmortem neuropathology in early Huntington disease
(Oxford University Press (OUP), 2024-03-29)Two aspects of the neuropathology of early Huntington disease (HD) are examined. Neurons of the neostriatum are counted to determine relative loss in striosomes versus matrix at early stages, including for the first time ... -
Postnatal Expansion of the Pancreatic \(\beta\)-Cell Mass Is Dependent on Survivin
(American Diabetes Association, 2008)Objective: Diabetes results from a deficiency of functional \(\beta\)-cells due to both an increase in \(\beta\)-cell death and an inhibition of \(\beta\)-cell replication. The molecular mechanisms responsible for these ... -
Postnatal onset of retinal degeneration by loss of embryonic Ezh2 repression of Six1
(Nature Publishing Group, 2016)Some adult-onset disorders may be linked to dysregulated embryonic development, yet the mechanisms underlying this association remain poorly understood. Congenital retinal degenerative diseases are blinding disorders ... -
Postoperative Care in an Intermediate-Level Medical Unit After Head and Neck Microvascular Free Flap Reconstruction
(Wiley, 2018-11-28)Objective: The need for intensive care unit (ICU) admission and mechanical ventilation after head and neck microvascular free flap reconstructive surgery remains controversial. Our institution has maintained a longstanding ... -
Postoperative Intensive Care Unit Requirements After Elective Craniotomy
(Elsevier BV, 2014)Objective: Commonly, patients undergoing craniotomy are admitted to an intensive care setting post-operatively to allow for close monitoring. We aim to determine the frequency with which patients who have undergone elective ... -
Postoperative Pain Management in DIEP Flap Breast Reconstruction: Identification of Patients With Poor Pain Control
(Open Science, 2010)Objective: Adequate control of postoperative pain directly improves patient satisfaction and outcomes, and timely identification of patients with poorly controlled pain is essential. Pain management protocols are best ... -
Postoperative pulmonary embolism in a three year old with Klippel–Trenaunay syndrome
(Dove Medical Press, 2009)Massive pulmonary embolism (PE) in a small child is a rare event and unified guidelines for its treatment are missing. Timely diagnosis and management of massive pulmonary embolism is of crucial importance for a good ... -
Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation
(Nature Publishing Group, 2016)Functional synapse formation requires tight coordination between pre- and post-synaptic termini. Previous studies have shown that postsynaptic expression of heparan sulfate proteoglycan syndecan-2 (SDC2) induces dendritic ... -
Posttraining Sleep Enhances Automaticity in Perceptual Discrimination
(Massachusetts Institute of Technology Press (MIT Press), 2004)Perceptual learning can develop over extended periods, with slow, at times sleep-dependent, improvement seen several days after training. As a result, performance can become more automatic, that is, less dependent on ... -
Posttranscriptional Control of Adipocyte Differentiation through Activation of Phosphoinositide 3-Kinase
(American Society for Biochemistry and Molecular Biology, 1998) -
Posttraumatic Distress Symptoms and Their Response to Treatment in Adults With Prolonged Grief Disorder
(Physicians Postgraduate Press, Inc, 2021-04-20)Objective: Posttraumatic stress disorder and Prolonged Grief Disorder (PGD) arise following major life stressors, and may share some overlapping symptomatology. This study aimed to examine the presence and response to ... -
Posttraumatic Psychological Symptoms are Associated with Reduced Inhibitory Control, not General Executive Dysfunction
(Cambridge University Press, 2015) -
Posttraumatic stress disorder, depression, and health-related quality of life in patients with bipolar disorder: Review and new data from a multi-site community clinic sample
(Elsevier BV, 2013)Background Evidence suggests that patients with bipolar disorder have an elevated risk for comorbid posttraumatic stress disorder (PTSD) compared to those without a bipolar diagnosis. Although bipolar disorder is ... -
Postural Changes in Blood Pressure Associated with Interactions between Candidate Genes for Chronic Respiratory Diseases and Exposure to Particulate Matter
(National Institute of Environmental Health Sciences, 2009)Background: Fine particulate matter [aerodynamic diameter ≤ 2.5 μm (PM2.5)] has been associated with autonomic dysregulation.Objective We hypothesized that PM2.5 influences postural changes in systolic blood pressure (ΔSBP) ...