Browsing HMS Scholarly Articles by Title
Now showing items 14509-14528 of 17922
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Retinoic Acid Can Enhance Conversion of Naive into Regulatory T Cells Independently of Secreted Cytokines
(The Rockefeller University Press, 2009)It has been reported that retinoic acid (RA) enhances regulatory T (T reg) cell conversion by inhibiting the secretion of cytokines that interfere with conversion. This report shows that these conclusions provide a partial ... -
The "Retinoic Acid Syndrome" in Acute Promyelocytic Leukemia
(American College of Physicians, 1992)OBJECTIVE: To describe a novel complication of therapy with all-trans retinoic acid in patients with acute promyelocytic leukemia. DESIGN: Case series. SETTING: Comprehensive cancer center. PATIENTS: Consecutive patients ... -
Retinoic acid-producing DCs and gut-tropic \(FOXP3^+\) regulatory T cells in the induction of oral tolerance
(Landes Bioscience, 2013)The systemic unresponsiveness of the immune system to orally administered antigens is known as oral tolerance. Recent findings describe a new step for the induction of oral tolerance, consisting in the homing of \(FOXP3^+\) ... -
Retinoid Metabolism and Diabetes Mellitus
(Korean Diabetes Association, 2012)Retinoid acid is a metabolite of vitamin A and functions as an important factor in cell survival, differentiation and death. Most previous studies on retinoid metabolism have focused on its association with cancer, hematologic ... -
Retinol binding protein 4 promotes hyperinsulinism-induced proliferation of rat aortic smooth muscle cells
(D.A. Spandidos, 2014)Recent studies have suggested that retinol binding protein 4 (RBP4), an adipocytokine related to insulin resistance (IR), may play an important role in the development of atherosclerosis and cardiovascular diseases (CVD). ... -
Retinopathy of prematurity
(Elsevier BV, 2013)The immature retinas of preterm neonates are susceptible to insults that disrupt neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors due to hyperoxia and loss of the maternal-fetal ... -
Retinopathy of prematurity: the need for prevention
(Dove Medical Press Ltd., 2016)More than 450,000 babies are born prematurely in the USA every year. The improved survival of even the most vulnerable low body weight preterm infants has, despite improving health outcomes, led to the resurgence in preterm ... -
Retraction of the Drosophila Germ Band Requires Cell-Matrix Interaction
(Cold Spring Harbor Laboratory, 2003-03-01)Integrins and laminins are important mediators of cell–matrix interactions in both vertebrates and invertebrates. Here, we show that germ-band retraction in the Drosophila embryo, during which the tail end of the embryo ... -
Retraction: Fatty Acid Synthase is a Novel Therapeutic Target in Multiple Myeloma
(Blackwell Publishing Ltd, 2008)This study investigated the biological significance of the inhibition of fatty acid synthase (FAS) in multiple myeloma (MM) using the small molecule inhibitor Cerulenin. Cerulenin triggered growth inhibition in both MM ... -
Retrievable stent thrombectomy in the treatment of acute ischemic stroke: Analysis of a revolutionizing treatment technique
(Elsevier BV, 2013)Acute ischemic stroke resulting from intracranial vessel occlusion is associated with high morbidity and mortality. The mainstays of therapy are fibrinolytics and mechanical thrombectomy in properly selected patients. A ... -
Retrieval of Radiology Reports Citing Critical Findings with Disease-Specific Customization
(Bentham Open, 2012)Background: Communication of critical results from diagnostic procedures between caregivers is a Joint Commission national patient safety goal. Evaluating critical result communication often requires manual analysis of ... -
Retrieval-induced forgetting in schizophrenia
(Elsevier BV, 2005)Retrieving category associates (e.g., FRUIT-ORANGE) may induce forgetting other category members (e.g., FRUIT-BANANA), a phenomenon known as retrieval-induced forgetting (RIF). We designed 2 experiments to examine the role ... -
Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain
(eLife Sciences Publications, Ltd, 2016)Communication between pre- and postsynaptic cells promotes the initial organization of synaptic specializations, but subsequent synaptic stabilization requires transcriptional regulation. Here we show that fibroblast growth ... -
Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons
(Company of Biologists, 2010)Mammalian limb and trunk skeletal muscles are composed of muscle fibers that differ in contractile and molecular properties. They are commonly divided into four categories according to the myosin heavy chain that they ... -
Retroperitoneal Laparoscopic Management of Paraganglioma: A Single Institute Experience
(Public Library of Science, 2016)Objectives: To explore the feasibility and safety of retroperitoneal laparoscopic resection of paraganglioma (RLPG) in a large study population. Methods: In a six-year period, 49 patients with primary retroperitoneal ... -
A retrospective chart review of drug treatment patterns and clinical outcomes among patients with metastatic or recurrent soft tissue sarcoma refractory to one or more prior chemotherapy treatments
(BioMed Central, 2015)Background: Limited clinical data on real-world practice patterns are available for patients with metastatic/relapsed soft tissue sarcomas (STS). The primary objective of this study was to evaluate treatment patterns in ... -
A Retrospective Cohort Study of U.S. Service Members Returning from Afghanistan and Iraq: Is Physical Health Worsening Over time?
(BioMed Central, 2012)Background: High rates of mental health disorders have been reported in veterans returning from deployment to Afghanistan (Operation Enduring Freedom: OEF) and Iraq (Operation Iraqi Freedom: OIF); however, less is known ... -
Retrospective cohort study of usage patterns of epidural injections for spinal pain in the US fee-for-service Medicare population from 2000 to 2014
(BMJ Publishing Group, 2016)Objective: To assess the usage patterns of epidural injections for chronic spinal pain in the fee-for-service (FFS) Medicare population from 2000 to 2014 in the USA. Design: A retrospective cohort. Methods: The descriptive ... -
Retrospective Evaluation of Elastic Stain in the Assessment of Serosal Invasion of pT3N0 Colorectal Cancers
(Ovid Technologies (Wolters Kluwer Health), 2013)Peritoneal involvement is an important adverse prognostic factor in colorectal cancer (CRC) and determines a shift in the pathologic tumor node metastasis stage. Because peritoneal involvement is difficult to identify, use ... -
Retroviral DNA Integration
(American Chemical Society, 2016)The integration of a DNA copy of the viral RNA genome into host chromatin is the defining step of retroviral replication. This enzymatic process is catalyzed by the virus-encoded integrase protein, which is conserved among ...