Browsing HMS Scholarly Articles by Title
Now showing items 1837-1856 of 17917
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Borderline symptoms and suicidality/self-injury in late adolescence: Prospectively observed relationship correlates in infancy and childhood
(Elsevier BV, 2013)The primary objective was to assess whether prospectively observed quality of parent–child interaction in infancy and middle childhood contributed to the prediction of borderline symptoms and recurrent suicidality/self-injury ... -
BORIS Promotes Chromatin Regulatory Interactions in Treatment-Resistant Cancer Cells
(Springer Science and Business Media LLC, 2019-08)The CCCTC-binding factor (CTCF), which anchors DNA loops that organize the genome into structural domains, plays a central role in gene control by facilitating or constraining interactions between genes and their regulatory ... -
Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging
(MyJove Corporation, 2009)Optical projection tomography is a three-dimensional imaging technique that has been recently introduced as an imaging tool primarily in developmental biology and gene expression studies. The technique renders biological ... -
Borrelia burgdorferi Stimulation of Chemokine Secretion by Cells of Monocyte Lineage in Patients with Lyme Arthritis
(BioMed Central, 2010)Introduction: Joint fluid in patients with Lyme arthritis often contains high levels of CCL4 and CCL2, which are chemoattractants for monocytes and some T cells, and CXCL9 and CXCL10, which are chemoattractants for CD4+ ... -
The Boston Assessment of Traumatic Brain Injury–Lifetime (BAT-L) Semistructured Interview: Evidence of Research Utility and Validity
Objective: Report the prevalence of lifetime and military-related traumatic brain injuries (TBIs) in Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF) veterans and validate the Boston Assessment of TBI–Lifetime ... -
Boston College daily sleep and well-being survey data during early phase of the COVID-19 pandemic
(Springer Science and Business Media LLC, 2021-04-16)<jats:title>Abstract</jats:title><jats:p>While there was a necessary initial focus on physical health consequences of the COVID-19 pandemic, it is becoming increasingly clear that many have experienced significant social ... -
Both high and low levels of cellular Epstein-Barr virus DNA in blood identify failure after hematologic stem cell transplantation in conjunction with acute GVHD and type of conditioning
(Impact Journals LLC, 2016)The level of Epstein-Barr virus DNA in blood has proven to be a biomarker with some predictive value in allogeneic hematopoietic stem cell transplantation patients (HSCT). We evaluated the impact of EBV load on survival ... -
Both Maternal and Pup Genotype Influence Ultrasonic Vocalizations and Early Developmental Milestones in Tsc2+/− Mice
(Hindawi Publishing Corporation, 2014)Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by tumor growth and neuropsychological symptoms such as autistic behavior, developmental delay, and epilepsy. While research has shed light ... -
Both the Structure and DNA Binding Function of the Barrier-to-Autointegration Factor Contribute to Reconstitution of HIV Type 1 Integration in Vitro
(American Society for Biochemistry and Molecular Biology, 2000) -
Bottlebrush polymers with flexible enantiomeric side chains display differential biological properties
(Springer Science and Business Media LLC, 2021-11-25)Chirality and molecular conformation are central components of life: from the genetic code and its inheritance mechanisms to cell surface receptors and trafficking pathways, biological systems rely on stereospecific ... -
Botulinum Neurotoxin D Uses Synaptic Vesicle Protein SV2 and Gangliosides as Receptors
(Public Library of Science, 2011)Botulinum neurotoxins (BoNTs) include seven bacterial toxins (BoNT/A-G) that target presynaptic terminals and act as proteases cleaving proteins required for synaptic vesicle exocytosis. Here we identified synaptic vesicle ... -
Bounding the per-protocol effect in randomized trials: an application to colorectal cancer screening
(BioMed Central, 2015)Background: The per-protocol effect is the effect that would have been observed in a randomized trial had everybody followed the protocol. Though obtaining a valid point estimate for the per-protocol effect requires ... -
BPAP for CPAP failures: For the many or the few
(Wiley, 2019-08-22) -
BPD's Interpersonal Hypersensitivity Phenotype: A Gene-Environment-Developmental Model
(Guilford Publications, 2008)This paper explores the development of BPD as it might emerge in the child's early interpersonal reactions and how such reactions might evolve into the interpersonal pattern that typifies BPD. It begins to bridge the ... -
Brachial Artery Responses to Ambient Pollution, Temperature, and Humidity in People with Type 2 Diabetes: A Repeated-Measures Study
(National Institute of Environmental Health Sciences, 2014)Background: Extreme weather and air pollution are associated with increased cardiovascular risk in people with diabetes. Objectives: In a population with diabetes, we conducted a novel assessment of vascular brachial artery ... -
Brachytherapy boost and cancer-specific mortality in favorable high-risk versus other high-risk prostate cancer
(Termedia Publishing House, 2016)Purpose Recent retrospective data suggest that brachytherapy (BT) boost may confer a cancer-specific survival benefit in radiation-managed high-risk prostate cancer. We sought to determine whether this survival benefit ... -
BRAF Activation Initiates but Does Not Maintain Invasive Prostate Adenocarcinoma
(Public Library of Science, 2008)Prostate cancer is the second leading cause of cancer-related deaths in men. Activation of MAP kinase signaling pathway has been implicated in advanced and androgen-independent prostate cancers, although formal genetic ... -
BRAF inhibition is associated with increased clonality in tumor-infiltrating lymphocytes
(Landes Bioscience, 2013)There have been significant advances with regard to BRAF-targeted therapies against metastatic melanoma. However, the majority of patients receiving BRAF inhibitors (BRAFi) manifest disease progression within a year. We ... -
BRAF V600E Mutations are Common in Pleomorphic Xanthoastrocytoma: Diagnostic and Therapeutic Implications
(Public Library of Science, 2011)Pleomorphic xanthoastrocytoma (PXA) is low-grade glial neoplasm principally affecting children and young adults. Approximately 40% of PXA are reported to recur within 10 years of primary resection. Upon recurrence, patients ... -
BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate
(Thieme Medical Publishers, 2013)Hemorrhagic pustules with a “blueberry muffin” appearance accompanied by respiratory failure in a neonate present a challenging differential diagnosis that includes infections and neoplasms. We present a case of multiorgan, ...