Browsing HMS Scholarly Articles by Title

Now showing items 3118-3137 of 17922

    • The compensatory dynamic of inter-hemispheric interactions in visuospatial attention revealed using rTMS and fMRI 

      Plow, Ela B.; Cattaneo, Zaira; Carlson, Thomas A.; Alvarez, George A.; Pascual-Leone, Alvaro; Battelli, Lorella (Frontiers Media S.A., 2014)
      A balance of mutual tonic inhibition between bi-hemispheric posterior parietal cortices is believed to play an important role in bilateral visual attention. However, experimental support for this notion has been mainly ...

    • Compensatory neural activity distinguishes different patterns of normal cognitive aging 

      Riis, Jenna L.; Chong, Hyemi; Ryan, Katherine K.; Wolk, David A.; Rentz, Dorene May; Holcomb, Phillip J.; Daffner, Kirk R. (Elsevier BV, 2008)
      Most cognitive neuroscientific research exploring the nature of age-associated compensatory mechanisms has compared old adults (high vs. average performers) to young adults (not split by performance), leaving ambiguous ...

    • Compensatory Response by Late Embryonic Tubular Epithelium to the Reduction in Pancreatic Progenitors 

      Nishimura, Wataru; Kapoor, Archana; El Khattabi, Ilham; Jin, Wanzhu; Yasuda, Kazuki; Bonner-Weir, Susan; Sharma, Arun (Public Library of Science, 2015)
      Early in pancreatic development, epithelial cells of pancreatic buds function as primary multipotent progenitor cells (1°MPC) that specify all three pancreatic cell lineages, i.e., endocrine, acinar and duct. Bipotent ...

    • Competitive performance of a modularized deep neural network compared to commercial algorithms for low-dose CT image reconstruction 

      Shan, Hongming; Padole, Atul; Homayounieh, Fatemeh; Kruger, Uwe; Khera, Ruhani Doda; Nitiwarangkul, Chayanin; Kalra, Mannudeep K.; Wang, Ge (Springer Science and Business Media LLC, 2019-06)
      Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine ...

    • Competitive performance of a modularized deep neural network compared to commercial algorithms for low-dose CT image reconstruction 

      Shan, Hongming; Padole, Atul; Homayounieh, Fatemeh; Kruger, Uwe; Doda Khera, Ruhani; Nitiwarangkul, Chayanin; K. Kalra, Mannudeep; Wang, GE (Springer Science and Business Media LLC, 2019-06)
      Commercial iterative reconstruction techniques help to reduce CT radiation dose but altered image appearance and artifacts limit their adoptability and potential use. Deep learning has been investigated for low-dose CT ...

    • Complement genes contribute sex-biased vulnerability in diverse disorders 

      Kamitaki, Nolan; Sekar, Aswin; Handsaker, Robert E.; de Rivera, Heather; Tooley, Katherine; Morris, David L.; Taylor, Kimberly E.; Whelan, Christopher W.; Tombleson, Philip; Loohuis, Loes M. Olde; Boehnke, Michael; Kimberly, Robert P.; Kaufman, Kenneth M.; Harley, John B.; Langefeld, Carl D.; Seidman, Christine; Pato, Michele T.; Pato, Carlos N.; Ophoff, Roel A.; Graham, Robert R.; Criswell, Lindsey A.; Vyse, Timothy J.; McCarroll, Steven (Springer Science and Business Media LLC, 2020-05-11)
      Many common illnesses differentially affect men and women for unknown reasons. The autoimmune diseases lupus and Sjögren’s syndrome affect nine times more women than men, whereas schizophrenia affects men more frequently ...

    • Complement Receptor 1 Is a Sialic Acid-Independent Erythrocyte Receptor of Plasmodium falciparum 

      Spadafora, Carmenza; Awandare, Gordon A.; Kopydlowski, Karen M.; Czege, Jozsef; Moch, J. Kathleen; Finberg, Robert W.; Tsokos, George C.; Stoute, José A. (Public Library of Science, 2010)
      Plasmodium falciparum is a highly lethal malaria parasite of humans. A major portion of its life cycle is dedicated to invading and multiplying inside erythrocytes. The molecular mechanisms of erythrocyte invasion are ...

    • Complementary and Alternative Medical Therapies for Chronic Low Back Pain: What Treatments are Patients Willing to Try? 

      Sherman, Karen J; Cherkin, Daniel C; Connelly, Maureen Therese; Erro, Janet; Savetsky, Jacqueline B; Davis, Roger B.; Eisenberg, David Miles (BioMed Central, 2004)
      Background: Although back pain is the most common reason patients use complementary and alternative medical (CAM) therapies, little is known about the willingness of primary care back pain patients to try these therapies. ...

    • Complementary and Alternative Medical Therapies in Multiple Sclerosis–The American Academy of Neurology Guidelines: A Commentary 

      Yadav, Vijayshree; Narayanaswami, Pushpa (Elsevier BV, 2014)
      Background: Complementary and alternative med- icine (CAM) use in individuals with multiple sclerosis (MS) is common, but its use has been limited by a lack of evidence-based guidance. Methods: In March 2014, the American ...

    • Complementary Genomic Screens Identify SERCA as a Therapeutic Target in NOTCH1 Mutated Cancer 

      Roti, Giovanni; Carlton, Anne; Ross, Kenneth; Markstein, Michele; Pajcini, Kostandin; Su, Angela H.; Perrimon, Norbert; Pear, Warren S.; Kung, Andrew L.; Blacklow, Stephen; Aster, Jon; Stegmaier, Kimberly (Elsevier BV, 2013-03-18)
      Notch1 is a rational therapeutic target in several human cancers, but as a transcriptional regulator, it poses a drug discovery challenge. To identify Notch1 modulators, we performed two cell-based, high-throughput screens ...

    • Complementary Medicine, Exercise, Meditation, Diet, and Lifestyle Modification for Anxiety Disorders: A Review of Current Evidence 

      Sarris, J.; Moylan, S.; Camfield, D. A.; Pase, M. P.; Mischoulon, David; Berk, M.; Jacka, F. N.; Schweitzer, I. (Hindawi Publishing Corporation, 2012)
      Use of complementary medicines and therapies (CAM) and modification of lifestyle factors such as physical activity, exercise, and diet are being increasingly considered as potential therapeutic options for anxiety disorders. ...

    • Complete and Partial Responses of the TEMPI Syndrome to Bortezomib 

      Schroyens, Wilfried; O'Connell, Casey; Sykes, David Brian (New England Journal of Medicine (NEJM/MMS), 2012)

    • Complete Androgen Insensitivity Syndrome 

      Sullivan, Benjamin; Evans, James E.; Cermack, Jennifer M.; Dana, Reza; Sullivan, David A. (American Medical Association (AMA), 2002)
      Objective To determine whether androgen receptors affect the fatty acid profiles of neutral and polar lipids in human meibomian gland secretions. Methods Meibomian gland secretion samples were obtained from both eyes ...

    • Complete Genes May Pass from Food to Human Blood 

      Spisák, Sándor; Solymosi, Norbert; Ittzés, Péter; Bodor, András; Kondor, Dániel; Vattay, Gábor; Barták, Barbara K.; Sipos, Ferenc; Galamb, Orsolya; Tulassay, Zsolt; Szállási, Zoltán; Rasmussen, Simon; Sicheritz-Ponten, Thomas; Brunak, Søren; Molnár, Béla; Csabai, István (Public Library of Science, 2013)
      Our bloodstream is considered to be an environment well separated from the outside world and the digestive tract. According to the standard paradigm large macromolecules consumed with food cannot pass directly to the ...

    • The Complete Genome and Proteome of Mycoplasma mobile 

      Jaffe, JD; Stange-Thomann, N; Smith, C; DeCaprio, D; Fisher, S; Butler, J; Calvo, S; Elkins, T; FitzGerald, MG; Hafez, N; Kodira, CD; Major, J; Wang, S; Wilkinson, J; Nicol, R; Nusbaum, C; Birren, B; Berg, HC; Church, George (Cold Spring Harbor Laboratory, 2004-08)
      Although often considered “minimal” organisms, mycoplasmas show a wide range of diversity with respect to host environment, phenotypic traits, and pathogenicity. Here we report the complete genomic sequence and proteogenomic ...

    • Complete genome of Staphylococcus aureus Tager 104 provides evidence of its relation to modern systemic hospital-acquired strains 

      Davis, Richard W.; Brannen, Andrew D.; Hossain, Mohammad J.; Monsma, Scott; Bock, Paul E.; Nahrendorf, Matthias; Mead, David; Lodes, Michael; Liles, Mark R.; Panizzi, Peter (BioMed Central, 2016)
      Background: Staphylococcus aureus (S. aureus) infections range in severity due to expression of certain virulence factors encoded on mobile genetic elements (MGE). As such, characterization of these MGE, as well as single ...

    • The complete genome sequence of a Neandertal from the Altai Mountains 

      Prüfer, Kay; Racimo, Fernando; Patterson, Nick; Jay, Flora; Sankararaman, Sriram; Sawyer, Susanna; Heinze, Anja; Renaud, Gabriel; Sudmant, Peter H.; de Filippo, Cesare; Li, Heng; Mallick, Swapan; Dannemann, Michael; Fu, Qiaomei; Kircher, Martin; Kuhlwilm, Martin; Lachmann, Michael; Meyer, Matthias; Ongyerth, Matthias; Siebauer, Michael; Theunert, Christoph; Tandon, Arti; Moorjani, Priya; Pickrell, Joseph; Mullikin, James C.; Vohr, Samuel H.; Green, Richard E.; Hellmann, Ines; Johnson, Philip L. F.; Blanche, Hélène; Cann, Howard; Kitzman, Jacob O.; Shendure, Jay; Eichler, Evan E.; Lein, Ed S.; Bakken, Trygve E.; Golovanova, Liubov V.; Doronichev, Vladimir B.; Shunkov, Michael V.; Derevianko, Anatoli P.; Viola, Bence; Slatkin, Montgomery; Reich, David; Kelso, Janet; Pääbo, Svante (2014)
      We present a high-quality genome sequence of a Neandertal woman from Siberia. We show that her parents were related at the level of half siblings and that mating among close relatives was common among her recent ancestors. ...

    • Complete Genome Sequence of Linezolid-Susceptible Staphylococcus haemolyticus Sh29/312/L2, a Clonal Derivative of a Linezolid-Resistant Clinical Strain 

      de Almeida, Lara M.; Pires, Carlos; Cerdeira, Louise T.; de Oliveira, Théo G. M.; McCulloch, John Anthony; Perez-Chaparro, Paula Juliana; Sacramento, Andrey G.; Brito, Artemir C.; da Silva, Joás L.; de Araújo, Maria Rita E.; Lincopan, Nilton; Martin, Melissa J.; Gilmore, Michael S.; Mamizuka, Elsa M. (American Society for Microbiology, 2015)
      We report the whole-genome sequence (WGS) of an in vitro susceptible derivative revertant mutant from a bloodstream isolate involved in a nosocomial outbreak in Brazil. The WGS comprises 2.5 Mb with 2,500 protein-coding ...

    • Complete Genome Sequence of Methanobacterium Thermoautotrophicum deltaH: Functional Analysis and Comparative Genomics 

      Smith, Douglas R.; Doucette-Stamm, Lynn; Deloughery, Craig; Lee, Hongmei; Dubois, Joann; Aldredge, Tyler; Bashirzadeh, Romina; Blakely, Derron; Cook, Robin; Gilbert, Katie; Keagle, Pamela; Hoang, Lieu; Harrison, Dawn; Lumm, Wendy; Pothier, Bryan; Qiu, Dayong; Spadafora, Rob; Vicaire, Rita; Wang, Ying; Wierzbowski, Jamey; Gibson, Rene; Jiwani, Nilofer; Caruso, Anthony; Bush, David; Safer, Hershel; Patwell, Donivan; Prabhakar, Shashi; McDougall, Steven; Shimer, George; Goyal, Anil; Pietrokovski, Shmuel; Church, George; Daniels, Charles; Mao, Jen-i; Rice, Phil; Nolling, Jork; Reeve, John (American Society for Microbiology, 1997)
      The complete 1,751,377-bp sequence of the genome of the thermophilic archaeon Methanobacterium thermoautotrophicum deltaH has been determined by a whole-genome shotgun sequencing approach. A total of 1,855 open reading ...

    • Complete Genome Sequence of Pseudomonas aeruginosa Phage AAT-1 

      Andrade-Domínguez, Andrés; Kolter, Roberto (American Society for Microbiology, 2016)
      Aspects of the interaction between phages and animals are of interest and importance for medical applications. Here, we report the genome sequence of the lytic Pseudomonas phage AAT-1, isolated from mammalian serum. AAT-1 ...