Browsing HMS Scholarly Articles by Title

Now showing items 4990-5009 of 17922

    • Effect of Bromocriptine-QR (a Quick-Release Formulation of Bromocriptine Mesylate) on Major Adverse Cardiovascular Events in Type 2 Diabetes Subjects 

      Gaziano, John Michael; Cincotta, Anthony H.; Vinik, Aaron; Blonde, Lawrence; Bohannon, Nancy; Scranton, Richard (Blackwell Publishing Ltd, 2012)
      Background: Bromocriptine-QR (a quick-release formulation of bromocriptine mesylate), a dopamine D2 receptor agonist, is a US Food and Drug Administrration–approved treatment for type 2 diabetes mellitus (T2DM). A 3070-subject ...

    • Effect of Calcium Supplementation on Blood Lead Levels in Pregnancy: A Randomized Placebo-Controlled Trial 

      Lamadrid-Figueroa, Héctor; Téllez-Rojo, Martha M.; Mercado-García, Adriana; Hu, Howard; Hernández-Avila, Mauricio; Ettinger, Adrienne S; Peterson, Karen E.; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2008)
      Background: Prenatal lead exposure is associated with deficits in fetal growth and neurodevelopment. Calcium supplementation may attenuate fetal exposure by inhibiting mobilization of maternal bone lead and/or intestinal ...

    • The effect of cangrelor and access site on ischaemic and bleeding events: insights from CHAMPION PHOENIX 

      Gutierrez, J. Antonio; Harrington, Robert A.; Blankenship, James C.; Stone, Gregg W.; Steg, Ph. Gabriel; Gibson, C. Michael; Hamm, Christian W.; Price, Matthew J.; Généreux, Philippe; Prats, Jayne; Deliargyris, Efthymios N.; Mahaffey, Kenneth W.; White, Harvey D.; Bhatt, Deepak L. (Oxford University Press, 2015)
      Aims To assess whether the use of the femoral or radial approach for percutaneous coronary intervention (PCI) interacted with the efficacy and safety of cangrelor, an intravenous P2Y12 inhibitor, in CHAMPION PHOENIX. Methods ...

    • Effect of Cardiogenic Shock Hospital Volume on Mortality in Patients With Cardiogenic Shock 

      Shaefi, Shahzad; O'Gara, Brian; Kociol, Robb D.; Joynt, Karen; Mueller, Ariel; Nizamuddin, Junaid; Mahmood, Eitezaz; Talmor, Daniel; Shahul, Sajid (Blackwell Publishing Ltd, 2014)
      Background: Cardiogenic shock (CS) is associated with significant morbidity, and mortality rates approach 40% to 60%. Treatment for CS requires an aggressive, sophisticated, complex, goal‐oriented, therapeutic regimen ...

    • Effect of Cell-Photosensitizer Binding and Cell Density on Microbial Photoinactivation 

      Demidova, T. N.; Hamblin, Michael; demidova (American Society for Microbiology, 2005-05-25)
      Photodynamic therapy involves the use of nontoxic dyes called photosensitizers and visible light to produce reactive oxygen species and cell killing. It is being studied as an alternative method of killing pathogens in ...

    • The effect of Chinese herbal medicine Jian Ling Decoction for the treatment of essential hypertension: a systematic review 

      Xiong, Xingjiang; Wang, Pengqian; Li, Xiaoke; Zhang, Yuqing (BMJ Publishing Group, 2015)
      Objectives: Jian Ling Decoction (JLD) is often prescribed to improve hypertension-related symptoms in China. However, this treatment has not been systematically reviewed for its efficacy against essential hypertension (EH). ...

    • Effect of Chronic Athletic Activity on Brown Fat in Young Women 

      Singhal, Vibha; Maffazioli, Giovana D.; Ackerman, Kate E.; Lee, Hang; Elia, Elisa F.; Woolley, Ryan; Kolodny, Gerald; Cypess, Aaron M.; Misra, Madhusmita (Public Library of Science, 2016)
      Background: The effect of chronic exercise activity on brown adipose tissue (BAT) is not clear, with some studies showing positive and others showing negative associations. Chronic exercise is associated with increased ...

    • Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts 

      Tan, Lin; Wang, Hui-Fu; Tan, Meng-Shan; Tan, Chen-Chen; Zhu, Xi-Chen; Miao, Dan; Yu, Wan-Jiang; Jiang, Teng; Tan, Lan; Yu, Jin-Tai; Weiner, Michael W.; Aisen, Paul; Petersen, Ronald; Jack, Clifford R.; Jagust, William; Trojanowki, John Q.; Toga, Arthur W.; Beckett, Laurel; Green, Robert C.; Saykin, Andrew J.; Morris, John; Shaw, Leslie M.; Kaye, Jeffrey; Quinn, Joseph; Silbert, Lisa; Lind, Betty; Carter, Raina; Dolen, Sara; Schneider, Lon S.; Pawluczyk, Sonia; Beccera, Mauricio; Teodoro, Liberty; Spann, Bryan M.; Brewer, James; Vanderswag, Helen; Fleisher, Adam; Heidebrink, Judith L.; Lord, Joanne L.; Mason, Sara S.; Albers, Colleen S.; Knopman, David; Johnson, Kris; Doody, Rachelle S.; Villanueva-Meyer, Javier; Chowdhury, Munir; Rountree, Susan; Dang, Mimi; Stern, Yaakov; Honig, Lawrence S.; Bell, Karen L.; Ances, Beau; Morris, John C.; Carroll, Maria; Creech, Mary L.; Franklin, Erin; Mintun, Mark A.; Schneider, Stacy; Oliver, Angela; Marson, Daniel; Griffith, Randall; Clark, David; Geldmacher, David; Brockington, John; Roberson, Erik; Love, Marissa Natelson; Grossman, Hillel; Mitsis, Effie; Shah, Raj C.; deToledo-Morrell, Leyla; Duara, Ranjan; Varon, Daniel; Greig, Maria T.; Roberts, Peggy; Albert, Marilyn; Onyike, Chiadi; D’Agostino, Daniel; Kielb, Stephanie; Galvin, James E.; Cerbone, Brittany; Michel, Christina A.; Pogorelec, Dana M.; Rusinek, Henry; de Leon, Mony J.; Glodzik, Lidia; De Santi, Susan; Doraiswamy, P. Murali; Petrella, Jeffrey R.; Borges-Neto, Salvador; Wong, Terence Z.; Coleman, Edward; Smith, Charles D.; Jicha, Greg; Hardy, Peter; Sinha, Partha; Oates, Elizabeth; Conrad, Gary; Porsteinsson, Anton P.; Goldstein, Bonnie S.; Martin, Kim; Makino, Kelly M.; Ismail, M. Saleem; Brand, Connie; Mulnard, Ruth A.; Thai, Gaby; Mc-Adams-Ortiz, Catherine; Womack, Kyle; Mathews, Dana; Quiceno, Mary; Levey, Allan I.; Lah, James J.; Cellar, Janet S.; Burns, Jeffrey M.; Swerdlow, Russell H.; Brooks, William M.; Apostolova, Liana; Tingus, Kathleen; Woo, Ellen; Silverman, Daniel H. S.; Lu, Po H.; Bartzokis, George; Graff-Radford, Neill R.; Parfitt, Francine; Kendall, Tracy; Johnson, Heather; Farlow, Martin R.; Hake, Ann Marie; Matthews, Brandy R.; Brosch, Jared R.; Herring, Scott; Hunt, Cynthia; van Dyck, Christopher H.; Carson, Richard E.; MacAvoy, Martha G.; Varma, Pradeep; Chertkow, Howard; Bergman, Howard; Hosein, Chris; Black, Sandra; Stefanovic, Bojana; Caldwell, Curtis; Hsiung, Ging-Yuek Robin; Feldman, Howard; Mudge, Benita; Assaly, Michele; Finger, Elizabeth; Pasternack, Stephen; Rachisky, Irina; Trost, Dick; Kertesz, Andrew; Bernick, Charles; Munic, Donna; Mesulam, Marek-Marsel; Lipowski, Kristine; Weintraub, Sandra; Bonakdarpour, Borna; Kerwin, Diana; Wu, Chuang-Kuo; Johnson, Nancy; Sadowsky, Carl; Villena, Teresa; Turner, Raymond Scott; Johnson, Kathleen; Reynolds, Brigid; Sperling, Reisa A.; Johnson, Keith A.; Marshall, Gad; Yesavage, Jerome; Taylor, Joy L.; Lane, Barton; Rosen, Allyson; Tinklenberg, Jared; Sabbagh, Marwan N.; Belden, Christine M.; Jacobson, Sandra A.; Sirrel, Sherye A.; Kowall, Neil; Killiany, Ronald; Budson, Andrew E.; Norbash, Alexander; Johnson, Patricia Lynn; Obisesan, Thomas O.; Wolday, Saba; Allard, Joanne; Lerner, Alan; Ogrocki, Paula; Tatsuoka, Curtis; Fatica, Parianne; Fletcher, Evan; Maillard, Pauline; Olichney, John; DeCarli, Charles; Carmichael, Owen; Kittur, Smita; Borrie, Michael; Lee, T -Y; Bartha, Rob; Johnson, Sterling; Asthana, Sanjay; Carlsson, Cynthia M.; Potkin, Steven G.; Preda, Adrian; Nguyen, Dana; Tariot, Pierre; Burke, Anna; Trncic, Nadira; Reeder, Stephanie; Bates, Vernice; Capote, Horacio; Rainka, Michelle; Scharre, Douglas W.; Kataki, Maria; Adeli, Anahita; Zimmerman, Earl A.; Celmins, Dzintra; Brown, Alice D.; Pearlson, Godfrey D.; Blank, Karen; Anderson, Karen; Flashman, Laura A.; Seltzer, Marc; Hynes, Mary L.; Santulli, Robert B.; Sink, Kaycee M.; Gordineer, Leslie; Williamson, Jeff D.; Garg, Pradeep; Watkins, Franklin; Ott, Brian R.; Querfurth, Henry; Tremont, Geoffrey; Salloway, Stephen; Malloy, Paul; Correia, Stephen; Rosen, Howard J.; Miller, Bruce L.; Perry, David; Mintzer, Jacobo; Spicer, Kenneth; Bachman, David; Pomara, Nunzio; Hernando, Raymundo; Sarrael, Antero; Relkin, Norman; Chaing, Gloria; Lin, Michael; Ravdin, Lisa; Smith, Amanda; Raj, Balebail Ashok; Fargher, Kristin (Nature Publishing Group, 2016)
      The Clusterin (CLU) gene, also known as apolipoprotein J (ApoJ), is currently the third most associated late-onset Alzheimer’s disease (LOAD) risk gene. However, little was known about the possible effect of CLU genetic ...

    • The Effect of Cluster Size Variability on Statistical Power in Cluster-Randomized Trials 

      Lauer, Stephen A.; Kleinman, Ken P.; Reich, Nicholas G. (Public Library of Science, 2015)
      The frequency of cluster-randomized trials (CRTs) in peer-reviewed literature has increased exponentially over the past two decades. CRTs are a valuable tool for studying interventions that cannot be effectively implemented ...

    • Effect of Computerized Physician Order Entry and a Team Intervention on Prevention of Serious Medication Errors 

      Bates, David; Leape, Lucian; Cullen, David J; Laird, Nan; Petersen, Laura A; Teich, Jonathan; Burdick, Elizabeth; Hickey, Mairead; Kleefield, Sharon; Shea, Brian; Vander Vliet, Martha; Seger, Diane L (American Medical Association (AMA), 1998-10-21)
      Context: Adverse drug events (ADEs) are a significant and costly cause of injury during hospitalization. Objectives: To evaluate the efficacy of 2 interventions for preventing nonintercepted serious medication errors, ...

    • Effect of Correlations on Network Controllability 

      Pósfai, Márton; Liu, Yang-Yu; Slotine, Jean-Jacques; Barabasi, Albert-Laszio (Nature Publishing Group, 2013)
      A dynamical system is controllable if by imposing appropriate external signals on a subset of its nodes, it can be driven from any initial state to any desired state in finite time. Here we study the impact of various ...

    • The effect of CPAP on HRQOL as Measured by the quality of Well-Being Self-Administered Questionnaire (QWB-SA) 

      Batool-Anwar, Salma; Omobomi, Olabimpe; Quan, Stuart (Southwest Journal of Pulmonary and Critical Care, 2020-01-14)
      Background: To examine the effect of continuous positive airway pressure (CPAP) on Health-related quality of life (HRQoL) as measured by the Quality of Well Being Self-Administered questionnaire (QWB-SA). Methods: ...

    • Effect of Cytomegalovirus Co-Infection on Normalization of Selected T-Cell Subsets in Children with Perinatally Acquired HIV Infection Treated with Combination Antiretroviral Therapy 

      Kapetanovic, Suad; Aaron, Lisa; Montepiedra, Grace; Anthony, Patricia; Thuvamontolrat, Kasalyn; Pahwa, Savita; Burchett, Sandra; Weinberg, Adriana; Kovacs, Andrea (Public Library of Science, 2015)
      Background: We examined the effect of cytomegalovirus (CMV) co-infection and viremia on reconstitution of selected CD4+ and CD8+ T-cell subsets in perinatally HIV-infected (PHIV+) children ≥ 1-year old who participated in ...

    • Effect of Desiccating Environmental Stress Versus Systemic Muscarinic AChR Blockade on Dry Eye Immunopathogenesis 

      Chen, Yihe; Chauhan, Sunil Kumar; Lee, Hyun Soo; Stevenson, William; Schaumburg, Chris S.; Sadrai, Zahra; Saban, Daniel R.; Kodati, Shilpa; Stern, Michael E.; Dana, Reza (Association for Research in Vision and Ophthalmology (ARVO), 2013)
      Purpose. A majority of experimental data on dry eye disease (DED) immunopathogenesis have been derived from a murine model of DED that combines desiccating environmental stress with systemic muscarinic acetylcholine ...

    • Effect of diet composition and weight loss on resting energy expenditure in the POUNDS LOST study 

      de Jonge, Lilian; Bray, George A.; Smith, Steven R.; Ryan, Donna H.; de Souza, Russell; Loria, Catherine M.; Champagne, Catherine M.; Williamson, Donald; Sacks, Frank M. (2012)
      Weight loss reduces energy expenditure, but it is unclear whether dietary macronutrient composition affects this reduction. We hypothesized that energy expenditure might be modulated by macronutrient composition of the ...

    • Effect of Dietary Composition of Weight Loss Diets on High Sensitivity C-Reactive Protein: The Randomized POUNDS LOST Trial 

      Nicklas, Jacinda M.; Sacks, Frank M.; Smith, Steven R.; LeBoff, Meryl S.; Rood, Jennifer C.; Bray, George A.; Ridker, Paul M (2012)
      Overweight and obesity are associated with increased high sensitivity C-reactive protein (hsCRP) levels. The purpose of this study was to determine if weight loss diets differing in fat, protein, or carbohydrate composition ...

    • The Effect of Dimethyl Fumarate on Cerebral Gray Matter Atrophy in Multiple Sclerosis 

      Dupuy, Sheena L.; Tauhid, Shahamat; Hurwitz, Shelley; Chu, Renxin; Yousuf, Fawad; Bakshi, Rohit (Springer Healthcare, 2016)
      Introduction: The objective of this pilot study was to compare cerebral gray matter (GM) atrophy over 1 year in patients starting dimethyl fumarate (DMF) for multiple sclerosis (MS) to that of patients on no disease-modifying ...

    • The Effect of Dose and Timing of Dose on the Association between Airborne Particles and Survival 

      Schwartz, Joel David; Coull, Brent Andrew; Laden, Francine; Ryan, Louise Marie (2008)
      BACKGROUND: Understanding the shape of the concentration–response curve for particles is important for public health, and lack of such understanding was recently cited by U.S. Environmental Protection Agency (EPA) as a ...

    • Effect of Environmental Tobacco Smoke on Levels of Urinary Hormone Markers 

      Wang, Xiaobin; Wang, Lihua; Yang, Fan; Tang, Genfu; Xing, Houxun; Lasley, Bill; Overstreet, James W.; Stanford, Joseph B.; Chen, ChangFeng; Ryan, Louise Marie; Xu, Xiang (National Institute of Environmental Health Sciences, 2005)
      Our recent study showed a dose–response relationship between environmental tobacco smoke (ETS) and the risk of early pregnancy loss. Smoking is known to affect female reproductive hormones. We explored whether ETS affects ...

    • The Effect of Fingolimod on Conversion of Acute Gadolinium-Enhancing Lesions to Chronic T1 Hypointensities in Multiple Sclerosis 

      Oommen Vinit, V; Tauhid, Shahamat; Healy Brian, C; Chua Alicia, S; Malik, MT; Diaz-Cruz, Camilo; Dupuy Sheena, L; Weiner Howard, L; Chitnis, Tanuja; Bakshi, Rohit (Wiley-Blackwell, 2015)
      BACKGROUND: Brain lesions converting to chronic T1 hypointensities (“chronic black holes” [CBH]), indicate severe tissue destruction (axonal loss and irreversible demyelination) in multiple sclerosis (MS). Two mechanisms ...