Browsing HMS Scholarly Articles by Title
Now showing items 5189-5208 of 17922
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Effects of gastrointestinal motility on obesity
(BioMed Central, 2014)Background: Changes of gastrointestinal motility, which are important related to the food digestion and absorption in the gastrointestinal tract, may be one of the factors in obesity-formation. Aims The changes of ... -
The Effects of Gender on the Neural Substrates of Pitch Memory
(MIT Press - Journals, 2003-08)Imaging studies have indicated that males and females differ anatomically in brain regions thought to underlie language functions. Functional studies have corroborated this difference by showing gender differences in terms ... -
Effects of gene imbalance on amyloid precursor protein [APP] expression in grafts and recipient cortex
(Hindawi Publishing Corporation, 1992) -
Effects of Genetic Variants Previously Associated with Fasting Glucose and Insulin in the Diabetes Prevention Program
(Public Library of Science, 2012)Common genetic variants have been recently associated with fasting glucose and insulin levels in white populations. Whether these associations replicate in pre-diabetes is not known. We extended these findings to the ... -
Effects of HDM2 antagonism on sunitinib resistance, p53 activation, SDF-1 induction, and tumor infiltration by CD11b+/Gr-1+ myeloid derived suppressor cells
(BioMed Central, 2013)Background: The studies reported herein were undertaken to determine if the angiostatic function of p53 could be exploited as an adjunct to VEGF-targeted therapy in the treatment of renal cell carcinoma (RCC). Methods: ... -
Effects of Health Maintenance Organization Coverage of Self-monitoring Devices on Diabetes Self-care and Glycemic Control
(American Medical Association (AMA), 2004)Background Increasingly, government mandates require insurance coverage of blood glucose monitors and test strips for patients with type 1 and type 2 diabetes. No data exist on the effects of such coverage on self-monitoring ... -
Effects of High vs Low Glycemic Index of Dietary Carbohydrate on Cardiovascular Disease Risk Factors and Insulin Sensitivity
(American Medical Association (AMA), 2014)Importance Foods that have similar carbohydrate content can differ in the amount they raise blood glucose. The effects of this property, called the glycemic index, on risk factors for cardiovascular disease and diabetes ... -
Effects of Hormone Therapy on Brain Volumes Changes of Postmenopausal Women Revealed by Optimally-Discriminative Voxel-Based Morphometry
(Public Library of Science, 2016)Backgrounds The Women's Health Initiative Memory Study Magnetic Resonance Imaging (WHIMS-MRI) provides an opportunity to evaluate how menopausal hormone therapy (HT) affects the structure of older women’s brains. Our earlier ... -
Effects of Hormone Therapy on Cognition and Mood in Recently Postmenopausal Women: Findings from the Randomized, Controlled KEEPS–Cognitive and Affective Study
(Public Library of Science, 2015)Background: Menopausal hormone therapy (MHT) reportedly increases the risk of cognitive decline in women over age 65 y. It is unknown whether similar risks exist for recently postmenopausal women, and whether MHT affects ... -
The Effects of Indoor Environmental Exposures on Pediatric Asthma: A Discrete Event Simulation Model
(BioMed Central, 2012)Background: In the United States, asthma is the most common chronic disease of childhood across all socioeconomic classes and is the most frequent cause of hospitalization among children. Asthma exacerbations have been ... -
The Effects of Industry Sponsorship on Comparator Selection in Trial Registrations for Neuropsychiatric Conditions in Children
(Public Library of Science, 2013)Pediatric populations continue to be understudied in clinical drug trials despite the increasing use of pharmacotherapy in children, particularly with psychotropic drugs. Most pertinent to the clinical selection of drug ... -
Effects of Inhaled Glucocorticoids on Bone Density in Premenopausal Women
(Massachusetts Medical Society, 2001-09-27)Inhaled glucocorticoids are the most commonly used medications for the long-term treatment of patients with asthma. Whether long-term therapy with inhaled glucocorticoids reduces bone mass, as oral glucocorticoid therapy ... -
Effects of Interfractional Anatomical Changes on Water-Equivalent Pathlength in Charged-Particle Radiotherapy of Lung Cancer
(Oxford University Press (OUP), 2009)Intrafractional motion and interfractional changes affect the accuracy of the delivered dose in radiotherapy, particularly in charged-particle radiotherapy. Most recent studies are focused on intrafractional motion ... -
Effects of intravenous administration of neurokinin receptor subtype-selective agonists on gonadotropin-releasing hormone pulse generator activity and luteinizing hormone secretion in goats
(The Society for Reproduction and Development, 2015)Recent evidence suggests that neurokinin B (NKB), a member of the neurokinin (tachykinin) peptide family, plays a pivotal role in gonadotropin-releasing hormone (GnRH) pulse generation. Three types of neurokinin receptors ... -
Effects of in vitro adult platelet transfusions on neonatal hemostasis
(Wiley-Blackwell, 2011)BACKGROUND: Thrombocytopenia is frequent among neonates, and 20-25% of affected infants are treated with platelet transfusions. These are frequently given for mild thrombocytopenia (platelets: 50-100 × 10(9) L(-1)), largely ... -
Effects of Laser Printer–Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts
(National Institute of Environmental Health Sciences, 2015)Background: Engineered nanomaterials (ENMs) incorporated into toner formulations of printing equipment become airborne during consumer use. Although information on the complex physicochemical and toxicological properties ... -
Effects of levomilnacipran ER on fatigue symptoms associated with major depressive disorder
(Lippincott Williams And Wilkins, 2016)The aim of this study was to evaluate the effects of levomilnacipran extended-release (ER) on depression-related fatigue in adults with major depressive disorder. Post-hoc analyses of five phase III trials were carried ... -
Effects of Liarozole Fumarate (R85246) in Combination with Tamoxifen on N-methyl-N-nitrosourea (MNU)-induced Mammary Carcinoma and Uterus in the Rat Model
(BioMed Central, 2007)Background: Liarozole fumarate (liarozole – R85246) is a novel compound with characteristics of both aromatase inhibitor (AI) and a retinoic acid metabolism blocking agent (RAMBA). Our objective was to determine the effects ... -
Effects of ligand activation of peroxisome proliferator-activated receptor γ in human prostate cancer
(National Academy of Sciences, 2000)Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear hormone receptor that plays a key role in the differentiation of adipocytes. Activation of this receptor in liposarcomas and breast and colon cancer ... -
Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles
(Elsevier BV, 2011)The engineering of drug-encapsulated targeted nanoparticles (NPs) has the potential to revolutionize drug therapy. A major challenge for the smooth translation of targeted NPs to the clinic has been developing methods for ...