Browsing HMS Scholarly Articles by Title
Now showing items 8350-8369 of 17921
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Impact of Emerging Health Insurance Arrangements on Diabetes Outcomes and Disparities: Rationale and Study Design
(Centers for Disease Control and Prevention, 2013)Consumer-directed health plans combine lower premiums with high annual deductibles, Internet-based quality-of-care information, and health savings mechanisms. These plans may encourage members to seek better value for ... -
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts
(Public Library of Science, 2016)Accumulation of somatic changes, due to environmental and endogenous lesions, in the human genome is associated with aging and cancer. Understanding the impacts of these processes on mutagenesis is fundamental to understanding ... -
Impact of false-positive newborn metabolic screening results on early health care utilization
(Springer Nature, 2009)Purpose: To analyze the association between false-positive newborn screening results and health care utilization. Methods: We surveyed parents regarding their children's health care utilization. Parents of children who ... -
The impact of feedback of intraoperative technical performance in surgery: a systematic review
(BMJ Publishing Group, 2015)Objectives: Increasing patient demands, costs and emphasis on safety, coupled with reductions in the length of time surgical trainees spend in the operating theatre, necessitate means to improve the efficiency of surgical ... -
Impact of Genotyping of Mycobacterium Tuberculosis on Public Health Practice in Massachusetts
(Centers for Disease Control and Prevention, 2002)Massachusetts was one of seven sentinel surveillance sites in the National Tuberculosis Genotyping and Surveillance Network. From 1996 through 2000, isolates from new patients with tuberculosis (TB) underwent genotyping. ... -
Impact of Global Geographic Region on Time in Therapeutic Range on Warfarin Anticoagulant Therapy: Data from the ROCKET AF Clinical Trial
(Blackwell Publishing, 2013)Background: Vitamin K antagonist (VKA) therapy remains the most common method of stroke prevention in patients with atrial fibrillation. Time in therapeutic range (TTR) is a widely cited measure of the quality of VKA ... -
Impact of Histone H4 Lysine 20 Methylation on 53BP1 Responses to Chromosomal Double Strand Breaks
(Public Library of Science, 2012)Recruitment of 53BP1 to chromatin flanking double strand breaks (DSBs) requires γH2AX/MDC1/RNF8-dependent ubiquitination of chromatin and interaction of 53BP1 with histone H4 methylated on lysine 20 (H4K20me). Several ... -
Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging
(Public Library of Science, 2014)Background: Chronic antigenic stimulation by cytomegalovirus (CMV) is thought to increase “immunosenesence” of aging, characterized by accumulation of terminally differentiated CD28- CD8+ T cells and increased CD57, a ... -
Impact of HIV on mortality among patients treated for tuberculosis in Lima, Peru: a prospective cohort study
(Springer Science + Business Media, 2015)Background: Human immunodeficiency virus (HIV)-associated tuberculosis deaths have decreased worldwide over the past decade. We sought to evaluate the effect of HIV status on tuberculosis mortality among patients ... -
Impact of HIV-related stigma on treatment adherence: systematic review and meta-synthesis
(International AIDS Society, 2013)Introduction: Adherence to HIV antiretroviral therapy (ART) is a critical determinant of HIV-1 RNA viral suppression and health outcomes. It is generally accepted that HIV-related stigma is correlated with factors that may ... -
Impact of IgA Constant Domain on HIV-1 Neutralizing Function of Monoclonal Antibody F425-A1g8
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Impact of implementing performance-based financing on childhood malnutrition in Rwanda
(BioMed Central, 2014)Background: Malnutrition remains a serious concern in Rwanda, particularly among children under-5 years. Performance-based financing (PBF), an innovative health systems financing strategy, has been implemented at the ... -
Impact of Insurance Status on Outcomes and Use of Rehabilitation Services in Acute Ischemic Stroke: Findings From Get With The Guidelines‐Stroke
(John Wiley and Sons Inc., 2016)Background: Insurance status affects access to care, which may affect health outcomes. The objective was to determine whether patients without insurance or with government‐sponsored insurance had worse quality of care or ... -
The Impact of Insurance Status on the Outcomes after Aneurysmal Subarachnoid Hemorrhage
(Public Library of Science, 2013)Investigation into the association of insurance status with the outcomes of patients undergoing neurosurgical intervention has been limited: this is the first nationwide study to analyze the impact of primary payer on the ... -
The Impact of Japan's 2004 Postgraduate Training Program on Intra-Prefectural Distribution of Pediatricians in Japan
(Public Library of Science, 2013)Objective: Inequity in physician distribution poses a challenge to many health systems. In Japan, a new postgraduate training program for all new medical graduates was introduced in 2004, and researchers have argued that ... -
The Impact of Lesion In-Painting and Registration Methods on Voxel-Based Morphometry in Detecting Regional Cerebral Gray Matter Atrophy in Multiple Sclerosis
(American Society of Neuroradiology (ASNR), 2012)Background and Purpose: VBM has been widely used to study GM atrophy in MS. MS lesions lead to segmentation and registration errors that may affect the reliability of VBM results. Improved segmentation and registration ... -
Impact of lung cancer screening results on participant health-related quality of life and state anxiety in the National Lung Screening Trial
(BlackWell Publishing Ltd, 2014)BACKGROUND Low-dose computed tomography (LDCT) lung screening has been associated with a 20% reduction in lung cancer mortality. A major barrier to the adoption of lung screening is the potential negative psychological ... -
Impact of MAPK Pathway Activation in BRAFV600 Melanoma on T Cell and Dendritic Cell Function
(Frontiers Media S.A., 2013)Constitutive upregulation of the MAPK pathway by a BRAFV600 mutation occurs in about half of melanomas. This leads to increased oncogenic properties such as tumor cell invasion, metastatic potential, and resistance to ... -
The Impact of Maternal Characteristics on the Moderately Premature Infant: An Antenatal Maternal Transport Clinical Prediction Rule
(Nature Publishing Group, 2012)Background: Moderately premature infants, defined here as those born between 30 \(\frac{0}{7}\) and 34 \(\frac{6}{7}\) weeks gestation, comprise 3.9% of all births in the United States and 32% of all preterm births. While ... -
The Impact of Medical Interpretation Method on Time and Errors
(Springer-Verlag, 2007)Background: Twenty-two million Americans have limited English proficiency. Interpreting for limited English proficient patients is intended to enhance communication and delivery of quality medical care. Objective: Little ...