Browsing HMS Scholarly Articles by Title

Now showing items 12339-12358 of 17921

    • Participation in Activity and Risk for Incident Delirium 

      Yang, Frances M.; Inouye, Sharon; Fearing, Michael A.; Kiely, Dan K.; Marcantonio, Edward Ralph; Jones, Richard Norman (Wiley-Blackwell, 2008)

    • Participation in physical activity in patients 1–4 years post total joint replacement in the Dominican Republic 

      Elman, Scott A; Dong, Yan; Stenquist, Derek S; Ghazinouri, Roya; Alcantara, Luis; Collins, Jamie E; Beagan, Carolyn; Thornhill, Thomas S; Katz, Jeffrey N (BioMed Central, 2014)
      Background: To address both the growing burden of joint disease and the gaps in medical access in developing nations, medical relief organizations have begun to launch programs to perform total joint replacement (TJR) on ...

    • Participatory Epidemiology: Use of Mobile Phones for Community-Based Health Reporting 

      Freifeld, Clark C.; Chunara, Rumi; Mekaru, Sumiko R.; Chan, Emily H.; Kass-Hout, Taha; Ayala Iacucci, Anahi; Brownstein, John Samuel (Public Library of Science, 2010)
      * Traditional health systems serve a key role in protecting populations, but are typically hierarchical, and information often travels slowly. * Novel Internet-based collaborative systems can have an important role in ...

    • Particulate Air Pollution and Fasting Blood Glucose in Nondiabetic Individuals: Associations and Epigenetic Mediation in the Normative Aging Study, 2000–2011 

      Peng, Cheng; Bind, Marie-Abele C.; Colicino, Elena; Kloog, Itai; Byun, Hyang-Min; Cantone, Laura; Trevisi, Letizia; Zhong, Jia; Brennan, Kasey; Dereix, Alexandra E.; Vokonas, Pantel S.; Coull, Brent A.; Schwartz, Joel D.; Baccarelli, Andrea A. (National Institute of Environmental Health Sciences, 2016)
      Background: Among nondiabetic individuals, higher fasting blood glucose (FBG) independently predicts diabetes risk, cardiovascular disease, and dementia. Ambient PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 ...

    • Particulate air pollution and survival in a COPD cohort 

      Zanobetti, Antonella; Bind, Marie-Abele Catherine; Schwartz, Joel David (BioMed Central, 2008)
      Background: Several studies have shown cross-sectional associations between long term exposure to particulate air pollution and survival in general population or convenience cohorts. Less is known about susceptibility, or ...

    • Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study 

      Hou, Lifang; Barupal, Jitendra; Zhang, Wei; Zheng, Yinan; Liu, Lei; Zhang, Xiao; Dou, Chang; McCracken, John P.; Díaz, Anaité; Motta, Valeria; Sanchez-Guerra, Marco; Wolf, Katherine Rose; Bertazzi, Pier Alberto; Schwartz, Joel D.; Wang, Sheng; Baccarelli, Andrea A. (National Institute of Environmental Health Sciences, 2015)
      Background: MicroRNAs (miRNAs) are post-transcriptional gene suppressors and potential mediators of environmental effects. In addition to human miRNAs, viral miRNAs expressed from latent viral sequences are detectable in ...

    • Particulate Air Pollution, Exceptional Aging, and Rates of Centenarians: A Nationwide Analysis of the United States, 1980–2010 

      Baccarelli, Andrea A.; Hales, Nick; Burnett, Richard T.; Jerrett, Michael; Mix, Carter; Dockery, Douglas W.; Pope, C. Arden (National Institute of Environmental Health Sciences, 2016)
      Background: Exceptional aging, defined as reaching age 85 years, shows geographic inequalities that may depend on local environmental conditions. Links between particulate pollution—a well-recognized environmental risk ...

    • Particulate air pollution, oxidative stress genes, and heart rate variability in an elderly cohort 

      Chahine, Teresa; Baccarelli, Andrea; Litonjua, Augusto Ampil; Wright, Robert O.; Suh MacIntosh, Helen H.; Gold, Diane R.; Sparrow, David; Vokonas, Pantel S; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2007)
      Background and Objectives: We have previously shown that reduced defenses against oxidative stress due to glutathione S-transferase M1 (GSTM1) deletion modify the effects of PM[2.5] (fine-particulate air pollution of < 2.5 ...

    • Particulate Matter (PM) Research Centers (1999–2005) and the Role of Interdisciplinary Center-based Research 

      Fanning, Elinor W.; Froines, John R.; Utell, Mark J.; Lippmann, Morton; Oberdörster, Gunter; Frampton, Mark; Larson, Tim V.; Godleski, John Joseph (National Institute of Environmental Health Sciences, 2008)
      Objective: The U.S. Environmental Protection Agency funded five academic centers in 1999 to address the uncertainties in exposure, toxicity, and health effects of airborne particulate matter (PM) identified in the “Research ...

    • Particulate Matter Air Pollution Exposure, Distance to Road, and Incident Lung Cancer in the Nurses’ Health Study Cohort 

      Puett, Robin C.; Hart, Jaime E.; Yanosky, Jeff D.; Spiegelman, Donna; Wang, Molin; Fisher, Jared A.; Hong, Biling; Laden, Francine (NLM-Export, 2014)
      Background: A body of literature has suggested an elevated risk of lung cancer associated with particulate matter and traffic-related pollutants. Objective: We examined the relation of lung cancer incidence with long-term ...

    • Particulate matter and risk of parkinson disease in a large prospective study of women 

      Palacios, Natalia; Fitzgerald, Kathryn C; Hart, Jaime E; Weisskopf, Marc G; Schwarzschild, Michael A; Ascherio, Alberto; Laden, Francine (BioMed Central, 2014)
      Background: Exposure to air pollution has been implicated in a number of adverse health outcomes and the effect of particulate matter (PM) on the brain is beginning to be recognized. Yet, no prospective study has examined ...

    • Partitioning heritability by functional annotation using genome-wide association summary statistics 

      Finucane, Hilary K.; Bulik-Sullivan, Brendan; Gusev, Alexander; Trynka, Gosia; Reshef, Yakir; Loh, Po-Ru; Anttila, Verneri; Xu, Han; Zang, Chongzhi; Farh, Kyle; Ripke, Stephan; Day, Felix R.; Consortium, ReproGen; Purcell, Shaun; Stahl, Eli; Lindstrom, Sara; Perry, John R. B.; Okada, Yukinori; Raychaudhuri, Soumya; Daly, Mark; Patterson, Nick; Neale, Benjamin M.; Price, Alkes L. (2015)
      Recent work has demonstrated that some functional categories of the genome contribute disproportionately to the heritability of complex diseases. Here, we analyze a broad set of functional elements, including cell-type-specific ...

    • Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture 

      Davis, Lea K.; Yu, Dongmei; Keenan, Clare L.; Gamazon, Eric R.; Konkashbaev, Anuar I.; Derks, Eske M.; Neale, Benjamin M.; Yang, Jian; Lee, S. Hong; Evans, Patrick; Barr, Cathy L.; Bellodi, Laura; Benarroch, Fortu; Berrio, Gabriel Bedoya; Bienvenu, Oscar J.; Bloch, Michael H.; Blom, Rianne M.; Bruun, Ruth D.; Budman, Cathy L.; Camarena, Beatriz; Campbell, Desmond; Cappi, Carolina; Cardona Silgado, Julio C.; Cath, Danielle C.; Cavallini, Maria C.; Chavira, Denise A.; Chouinard, Sylvain; Conti, David V.; Cook, Edwin H.; Coric, Vladimir; Cullen, Bernadette A.; Deforce, Dieter; Delorme, Richard; Dion, Yves; Edlund, Christopher K.; Egberts, Karin; Falkai, Peter; Fernandez, Thomas V.; Gallagher, Patience J.; Garrido, Helena; Geller, Daniel; Girard, Simon L.; Grabe, Hans J.; Grados, Marco A.; Greenberg, Benjamin D.; Gross-Tsur, Varda; Haddad, Stephen; Heiman, Gary A.; Hemmings, Sian M. J.; Hounie, Ana G.; Illmann, Cornelia; Jankovic, Joseph; Jenike, Michael A.; Kennedy, James L.; King, Robert A.; Kremeyer, Barbara; Kurlan, Roger; Lanzagorta, Nuria; Leboyer, Marion; Leckman, James F.; Lennertz, Leonhard; Liu, Chunyu; Lochner, Christine; Lowe, Thomas L.; Macciardi, Fabio; McCracken, James T.; McGrath, Lauren M.; Mesa Restrepo, Sandra C.; Moessner, Rainald; Morgan, Jubel; Muller, Heike; Murphy, Dennis L.; Naarden, Allan L.; Ochoa, William Cornejo; Ophoff, Roel A.; Osiecki, Lisa; Pakstis, Andrew J.; Pato, Michele T.; Pato, Carlos N.; Piacentini, John; Pittenger, Christopher; Pollak, Yehuda; Rauch, Scott L.; Renner, Tobias J.; Reus, Victor I.; Richter, Margaret A.; Riddle, Mark A.; Robertson, Mary M.; Romero, Roxana; Rosàrio, Maria C.; Rosenberg, David; Rouleau, Guy A.; Ruhrmann, Stephan; Ruiz-Linares, Andres; Sampaio, Aline S.; Samuels, Jack; Sandor, Paul; Sheppard, Brooke; Singer, Harvey S.; Smit, Jan H.; Stein, Dan J.; Strengman, E.; Tischfield, Jay A.; Valencia Duarte, Ana V.; Vallada, Homero; Van Nieuwerburgh, Filip; Veenstra-VanderWeele, Jeremy; Walitza, Susanne; Wang, Ying; Wendland, Jens R.; Westenberg, Herman G. M.; Shugart, Yin Yao; Miguel, Euripedes C.; McMahon, William; Wagner, Michael; Nicolini, Humberto; Posthuma, Danielle; Hanna, Gregory L.; Heutink, Peter; Denys, Damiaan; Arnold, Paul D.; Oostra, Ben A.; Nestadt, Gerald; Freimer, Nelson B.; Pauls, David L.; Wray, Naomi R.; Stewart, S. Evelyn; Mathews, Carol A.; Knowles, James A.; Cox, Nancy J.; Scharf, Jeremiah M. (Public Library of Science, 2013)
      The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated ...

    • Partner testing, linkage to care, and HIV-free survival in a program to prevent parent-to-child transmission of HIV in the Highlands of Papua New Guinea 

      Carmone, Andy; Bomai, Korai; Bongi, Wayaki; Frank, Tarua Dale; Dalepa, Huleve; Loifa, Betty; Kiromat, Mobumo; Das, Sarthak; Franke, Molly F. (Co-Action Publishing, 2014)
      Background: To eliminate new pediatric HIV infections, interventions that facilitate adherence, including those that minimize stigma, enhance social support, and mitigate the influence of poverty, will likely be required ...

    • Partnering with health system operations leadership to develop a controlled implementation trial 

      Bauer, Mark S.; Miller, Christopher; Kim, Bo; Lew, Robert; Weaver, Kendra; Coldwell, Craig; Henderson, Kathy; Holmes, Sally; Seibert, Marjorie Nealon; Stolzmann, Kelly; Elwy, A. Rani; Kirchner, JoAnn (BioMed Central, 2016)
      Background: Outcome for mental health conditions is suboptimal, and care is fragmented. Evidence from controlled trials indicates that collaborative chronic care models (CCMs) can improve outcomes in a broad array of mental ...

    • Partnerships in mental healthcare service delivery in low-resource settings: developing an innovative network in rural Nepal 

      Acharya, Bibhav; Maru, Duncan; Schwarz, Ryan; Citrin, David; Tenpa, Jasmine; Hirachan, Soniya; Basnet, Madhur; Thapa, Poshan; Swar, Sikhar; Halliday, Scott; Kohrt, Brandon; Luitel, Nagendra P.; Hung, Erick; Gauchan, Bikash; Pokharel, Rajeev; Ekstrand, Maria (BioMed Central, 2017)
      Background: Mental illnesses are the largest contributors to the global burden of non-communicable diseases. However, there is extremely limited access to high quality, culturally-sensitive, and contextually-appropriate ...

    • Passive Immunization against Pyroglutamate-3 Amyloid-β Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study 

      Frost, Jeffrey L.; Liu, Bin; Kleinschmidt, Martin; Schilling, Stephan; Demuth, Hans-Ulrich; Lemere, Cynthia A. (S. Karger AG, 2012)
      Background: N-terminally truncated and modified pyroglutamate-3 amyloid-β protein (pE3-Aβ) is present in most, if not all, cerebral plaque and vascular amyloid deposits in human Alzheimer's disease (AD). pE3-Aβ deposition ...

    • Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose 

      Sholukh, Anton M; Byrareddy, Siddappa N; Shanmuganathan, Vivekanandan; Hemashettar, Girish; Lakhashe, Samir K; Rasmussen, Robert A; Watkins, Jennifer D; Vyas, Hemant K; Thorat, Swati; Brandstoetter, Tania; Mukhtar, Muhammad M; Yoon, John K; Novembre, Francis J; Villinger, Francois; Landucci, Gary; Forthal, Donald N; Ratcliffe, Sarah; Tuero, Iskra; Robert-Guroff, Marjorie; Polonis, Victoria R; Bilska, Miroslawa; Montefiori, David C; Johnson, Welkin E; Ertl, Hildegund C; Ruprecht, Ruth M (BioMed Central, 2014)
      Background: A key goal for HIV-1 envelope immunogen design is the induction of cross-reactive neutralizing antibodies (nAbs). As AIDS vaccine recipients will not be exposed to strains exactly matching any immunogens due ...

    • Passive immunization with polyclonal anti-SHIV IgG: partial protection or increased acquisition of heterologous tier 2 SHIV – depending on IgG dose 

      Sholukh, Anton M; Siddappa, NB; Shanmuganathan, V; Lakhashe, Samir; Rasmussen, Robert Anthony; Watkins, Jennifer D; Vyas, Hemant Kumar; Mukhtar, Muhammad Mahmood; Hemashettar, G; Thorat, Swati; Yoon, JK; Villinger, F; Novembre, FJ; Landucci, G; Forthal, DN; Ratcliffe, S; Robert-Guroff, M; Polonis, V; Montefiori, DC; Ertl, HC; Ruprecht, Ruth Margrit (BioMed Central, 2012)

    • Passive Markers for Tracking Surgical Instruments in Real-Time 3-D Ultrasound Imaging 

      Stoll, J.; Ren, H.; Dupont, Pierre E (Institute of Electrical and Electronics Engineers (IEEE), 2012)
      A family of passive echogenic markers is presented by which the position and orientation of a surgical instrument can be determined in a 3-D ultrasound volume, using simple image processing. Markers are attached near the ...