Browsing HMS Scholarly Articles by Title

Now showing items 1307-1326 of 17922

    • Associations of cord blood metabolites with early childhood obesity risk 

      Isganaitis, Elvira; Rifas-Shiman, Sheryl L.; Oken, Emily; Dreyfuss, Jonathan; Gall, Walt; Gillman, Matthew W.; Patti, Mary-Elizabeth (2015)
      Background/Objective Rapid postnatal weight gain is a potentially modifiable risk factor for obesity and metabolic syndrome. To identify markers of rapid infancy weight gain and childhood obesity, we analyzed the metabolome ...

    • Associations of Early Childhood Manganese and Lead Coexposure with Neurodevelopment 

      Henn, Birgit Claus; Schnaas, Lourdes; Lamadrid-Figueroa, Héctor; Hernández-Avila, Mauricio; Hu, Howard; Téllez-Rojo, Martha María; Ettinger, Adrienne S; Schwartz, Joel David; Amarasiriwardena, Chitra J.; Bellinger, David C.; Wright, Robert O. (National Institute of Environmental Health Sciences, 2011)
      Background: Most toxicologic studies focus on a single agent, although this does not reflect real-world scenarios in which humans are exposed to multiple chemicals. Objectives: We prospectively studied manganese–lead ...

    • Associations of Fine Particulate Matter Species with Mortality in the United States: A Multicity Time-Series Analysis 

      Dai, Lingzhen; Zanobetti, Antonella; Koutrakis, Petros; Schwartz, Joel D. (NLM-Export, 2014)
      Background: Epidemiological studies have examined the association between PM2.5 and mortality, but uncertainty remains about the seasonal variations in PM2.5-related effects and the relative importance of species. Objectives: ...

    • Associations of Leg Fat Accumulation with Adiposity-Related Biological Factors and Risk of Metabolic Syndrome 

      Zhang, Xiaomin; Hu, Emily A.; Wu, Hongyu; Malik, Vasanti; Sun, Qi (2012)
      The association between regional fat mass distribution and cardiometabolic risk factors has been inconsistent in the literature, and data for ethnic minority groups, such as non-Hispanic blacks and Hispanics, are lacking. ...

    • The associations of leg lean mass with foot pain, posture and function in the Framingham foot study 

      McLean, Robert R; Dufour, Alyssa B; Katz, Patricia P; Hillstrom, Howard J; Hagedorn, Thomas J; Hannan, Marian T (BioMed Central, 2014)
      Background: Foot disorders are common in older adults and associated with impaired lower extremity function. Reduced muscle mass may play a role in the etiology of foot disorders and consequent poor function. Methods: We ...

    • Associations of Peripubertal Serum Dioxin and Polychlorinated Biphenyl Concentrations with Pubertal Timing among Russian Boys 

      Burns, Jane S.; Lee, Mary M.; Williams, Paige L.; Korrick, Susan A.; Sergeyev, Oleg; Lam, Thuy; Revich, Boris; Hauser, Russ (National Institute of Environmental Health Sciences, 2016)
      Background: Dioxins, furans, and polychlorinated biphenyls (PCBs), dioxin-like and non-dioxin-like, have been linked to alterations in puberty. Objectives: We examined the association of peripubertal serum levels of these ...

    • Associations of Plasma Phospholipid and Dietary Alpha Linolenic Acid With Incident Atrial Fibrillation in Older Adults: The Cardiovascular Health Study 

      Fretts, Amanda M.; Mozaffarian, Dariush; Siscovick, David S.; Heckbert, Susan R.; McKnight, Barbara; King, Irena B.; Rimm, Eric B.; Psaty, Bruce M.; Sacks, Frank Martin; Song, Xiaoling; Spiegelman, Donna Lynn; Lemaitre, Rozenn N. (Blackwell Publishing Ltd, 2013)
      Background: Few studies have examined the relationship of α‐linolenic acid (ALA 18:3n‐3), an intermediate‐chain essential n‐3 polyunsaturated fatty acid derived from plants and vegetable oils, with incident atrial fibrillation ...

    • Associations of Prenatal Nicotine Exposure and the Dopamine Related Genes ANKK1 and DRD2 to Verbal Language 

      Eicher, John D.; Powers, Natalie R.; Cho, Kelly; Miller, Laura L.; Mueller, Kathryn L.; Ring, Susan M.; Tomblin, J. Bruce; Gruen, Jeffrey R. (Public Library of Science, 2013)
      Language impairment (LI) and reading disability (RD) are common pediatric neurobehavioral disorders that frequently co-occur, suggesting they share etiological determinants. Recently, our group identified prenatal nicotine ...

    • Associations of Radiomic Data Extracted from Static and Respiratory-Gated CT Scans with Disease Recurrence in Lung Cancer Patients Treated with SBRT 

      Huynh, Elizabeth; Coroller, Thibaud P.; Narayan, Vivek; Agrawal, Vishesh; Romano, John; Franco, Idalid; Parmar, Chintan; Hou, Ying; Mak, Raymond H.; Aerts, Hugo J. W. L. (Public Library of Science, 2017)
      Radiomics aims to quantitatively capture the complex tumor phenotype contained in medical images to associate them with clinical outcomes. This study investigates the impact of different types of computed tomography (CT) ...

    • Associations of Toenail Arsenic, Cadmium, Mercury, Manganese, and Lead with Blood Pressure in the Normative Aging Study 

      Mordukhovich, Irina; Wright, Robert O.; Hu, Howard; Amarasiriwardena, Chitra J.; Baccarelli, Andrea; Litonjua, Augusto Ampil; Sparrow, David; Vokonas, Pantel S; Schwartz, Joel David (National Institute of Environmental Health Sciences, 2012)
      Background: Arsenic, cadmium, mercury, and lead are associated with cardiovascular disease in epidemiologic research. These associations may be mediated by direct effects of the metals on blood pressure (BP) elevation. ...

    • Associations of Trauma Exposure and Posttraumatic Stress Symptoms With Venous Thromboembolism Over 22 Years in Women 

      Sumner, Jennifer A.; Kubzansky, Laura D.; Kabrhel, Christopher; Roberts, Andrea L.; Chen, Qixuan; Winning, Ashley; Gilsanz, Paola; Rimm, Eric B.; Glymour, Maria M.; Koenen, Karestan C. (John Wiley and Sons Inc., 2016)
      Background: Trauma exposure and posttraumatic stress disorder (PTSD) have been linked to myocardial infarction and stroke in women, with biological and behavioral mechanisms implicated in underlying risk. The third most ...

    • Associative memory in chronic schizophrenia: a computational model 

      Han, S Duke; Nestor, Paul Gerard; Shenton, Martha Elizabeth; Niznikiewicz, Margaret A.; Hannah, Gordon; McCarley, Robert William (Elsevier BV, 2003)
      We developed a computer model to simulate associative memory recall of patients with chronic schizophrenia. Model inputs consisted of words derived from normative data that differed in terms of connectivity and network ...

    • Asthma and Genes Encoding Components of the Vitamin D Pathway 

      Bossé, Yohan; Lemire, Mathieu; Poon, Audrey H; Daley, Denise; He, Jian-Qing; Sandford, Andrew; James, Alan L; Musk, Arthur William; Palmer, Lyle J; Kozyrskyj, Anita L; Becker, Allan; Hudson, Thomas J; Laprise, Catherine; White, John H.; Raby, Benjamin Alexander; Weiss, Scott Tillman (BioMed Central, 2009)
      Background: Genetic variants at the vitamin D receptor (VDR) locus are associated with asthma and atopy. We hypothesized that polymorphisms in other genes of the vitamin D pathway are associated with asthma or atopy. ...

    • Asthma Associates With Human Abdominal Aortic Aneurysm and RuptureSignificance 

      Liu, Cong-Lin; Wemmelund, Holger; Wang, Yi; Liao, Mengyang; Lindholt, Jes S.; Johnsen, Søren P.; Vestergaard, Henrik; Fernandes, Cleverson; Sukhova, Galina K.; Cheng, Xiang; Zhang, Jin-Ying; Yang, Chongzhe; Huang, Xiaozhu; Daugherty, Alan; Levy, Bruce David; Libby, Peter; Shi, Guo-Ping (Ovid Technologies (Wolters Kluwer Health), 2016)
      Objective—Both asthma and abdominal aortic aneurysms (AAA) involve inflammation. It remains unknown whether these diseases interact. Approach and Results—Databases analyzed included Danish National Registry of Patients, ...

    • Asthma Is More Severe in Older Adults 

      Zein, Joe G.; Dweik, Raed A.; Comhair, Suzy A.; Bleecker, Eugene R.; Moore, Wendy C.; Peters, Stephen P.; Busse, William W.; Jarjour, Nizar N.; Calhoun, William J.; Castro, Mario; Chung, K. Fan; Fitzpatrick, Anne; Israel, Elliot; Teague, W. Gerald; Wenzel, Sally E.; Love, Thomas E.; Gaston, Benjamin M.; Erzurum, Serpil C. (Public Library of Science, 2015)
      Background: Severe asthma occurs more often in older adult patients. We hypothesized that the greater risk for severe asthma in older individuals is due to aging, and is independent of asthma duration. Methods: This is a ...

    • Asthma Self-assessment in a Medicaid Population 

      Wu, Ann Chen; Glauber, James Howard; Gay, Charlene; Lieu, Tracy Ann (BioMed Central, 2009)
      Background: Self-assessment of symptoms by patients with chronic conditions is an important element of disease management. A recent study in a commercially-insured population found that patients who received automated ...

    • Asthma Treatments and Mental Health Visits After a Food and Drug Administration Label Change for Leukotriene Inhibitors 

      Lu, Christine; Zhang, Fang; Lakoma, Matthew D.; Butler, Melissa G.; Fung, Vicki; Larkin, Emma K.; Kharbanda, Elyse O.; Vollmer, William M.; Lieu, Tracy; Soumerai, Stephen Bertram; Chen Wu, Ann (Elsevier BV, 2015)
      Purpose In 2009, the US Food and Drug Administration (FDA) mandated a label change for leukotriene inhibitors (LTIs) to include neuropsychiatric adverse events (eg, depression and suicidality) as a precaution. This study ...

    • Asthma-susceptibility variants identified using probands in case-control and family-based analyses 

      Murphy, Amy J; Soto-Quiros, Manuel E; Avila, Lydiana; Celedón, Juan C; O'Connor, George T; Himes, Blanca Elena; Su, Jessica Ann Lasky; Wu, Ann Chen; Wilk, Jemma B; Hunninghake, Gary Matthew; Klanderman, Barbara Jordan; Lazarus, Ross; Lange, Christoph; Raby, Benjamin Alexander; Silverman, Edwin Kepner; Weiss, Scott Tillman (BioMed Central, 2010)
      Background: Asthma is a chronic respiratory disease whose genetic basis has been explored for over two decades, most recently via genome-wide association studies. We sought to find asthma-susceptibility variants by using ...

    • Astrocyte regulation of sleep circuits: experimental and modeling perspectives 

      Fellin, Tommaso; Ellenbogen, Jeffery M.; De Pittà, Maurizio; Ben-Jacob, Eshel; Halassa, Michael (Frontiers Media S.A., 2012)
      Integrated within neural circuits, astrocytes have recently been shown to modulate brain rhythms thought to mediate sleep function. Experimental evidence suggests that local impact of astrocytes on single synapses translates ...

    • Astrocyte-Specific Disruption of SynCAM1 Signaling Results in ADHD-Like Behavioral Manifestations 

      Sandau, Ursula S.; Alderman, Zefora; Corfas, Gabriel; Ojeda, Sergio R.; Raber, Jacob (Public Library of Science, 2012)
      SynCAM1 is an adhesion molecule involved in synaptic differentiation and organization. SynCAM1 is also expressed in astroglial cells where it mediates astrocyte-to astrocyte and glial-neuronal adhesive communication. In ...