Browsing HMS Scholarly Articles by Title
Now showing items 14039-14058 of 17918
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Recognition of Depressive Symptoms by Physicians
(Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 2009)OBJECTIVE: To investigate the recognition of depressive symptoms of major depressive disorder (MDD) by general practitioners. INTRODUCTION: MDD is underdiagnosed in medical settings, possibly because of difficulties in the ... -
Recognition of Facial Expressions by Seven-Month-Old Infants
(Wiley, 1979)3 experiments examined 7-month-old infants' ability to discriminate the facial expressions of happy vs. fear. Experiment 1 revealed that infants demonstrated discrimination of happy vs. fear expressions when posed by a ... -
Recognition of HIV-1 Peptides by Host CTL Is Related to HIV-1 Similarity to Human Proteins
(Public Library of Science, 2007)Background: While human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes preferentially target specific regions of the viral proteome, HIV-1 features that contribute to immune recognition are not well ... -
Recognition of Phosphodegron Motifs in Human Cyclin E by the SCF Fbw7 Ubiquitin Ligase
(American Society for Biochemistry and Molecular Biology, 2004)Turnover of cyclin E is controlled by SCFFbw7. Three isoforms of Fbw7 are produced by alternative splicing. Whereas Fbw7alpha and -gamma are nuclear and the beta-isoform is cytoplasmic in 293T cells, all three isoforms ... -
Recognition of the centromere-specific histone Cse4 by the chaperone Scm3
(National Academy of Sciences, 2011)A specialized nucleosome is a component of all eukaryotic kinetochores. The core of this nucleosome contains a centromere-specific histone, CENP-A (the Cse4 gene product in budding yeast), instead of the usual H3. Assembly ... -
Recognizing and managing sepsis: what needs to be done?
(BioMed Central, 2015)Sepsis is associated with significant morbidity and mortality if not promptly recognized and treated. Since the development of early goal-directed therapy, mortality rates have decreased, but sepsis remains a major cause ... -
Recognizing Delirium Superimposed on Dementia
(Healio, 2007)Delirium is a serious and prevalent problem that occurs in many hospitalized older adults. Delirium superimposed on dementia (DSD) occurs when a delirium occurs concurrently with a pre-existing dementia. DSD is typically ... -
Recognizing the cooperative and independent mitochondrial functions of Parkin and PINK1
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Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice
(2016)Anti-factor VIII (FVIII) antibodies is a major complication of FVIII replacement therapy for hemophilia A. We investigated the immune response to recombinant human factor VIII Fc (rFVIIIFc) in comparison to BDD-rFVIII and ... -
Recombinant human thrombomodulin inhibits neutrophil extracellular trap formation in vitro
(BioMed Central, 2016)The aim of this study was to investigate the effects of recombinant human-soluble thrombomodulin (rTM) on lipopolysaccharide (LPS)-induced, platelet-dependent neutrophil extracellular trap (NET) formation (NETosis). Human ... -
Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates
(Public Library of Science, 2012)The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. Among the most promising filovirus vaccines under development is a system based on recombinant ... -
Recombinational DNA Repair in Cancer and Normal Cells: The Challenge of Functional Analysis
(Hindawi Publishing Corporation, 2002)A major goal of current cancer research is to understand the functional consequences of mutations in recombinational DNA repair genes. The introduction of artificial recombination substrates into living cells has evolved ... -
Recommendations for Cardiovascular Magnetic Resonance in Adults with Congenital Heart Disease from the Respective Working Groups of the European Society of Cardiology
(Oxford University Press, 2010)This paper aims to provide information and explanations regarding the clinically relevant options, strengths, and limitations of cardiovascular magnetic resonance (CMR) in relation to adults with congenital heart disease ... -
Recommendations for imaging tumor response in neurofibromatosis clinical trials
(Ovid Technologies (Wolters Kluwer Health), 2013)Objective: Neurofibromatosis (NF)-related benign tumors such as plexiform neurofibromas (PN) and vestibular schwannomas (VS) can cause substantial morbidity. Clinical trials directed at these tumors have become available. ... -
Recommendations for open data science
(BioMed Central, 2016)Life science research increasingly relies on large-scale computational analyses. However, the code and data used for these analyses are often lacking in publications. To maximize scientific impact, reproducibility, and ... -
Recommendations for the Diagnosis and Initial Evaluation of Patients with Waldenström Macroglobulinaemia: A Task Force from the 8th International Workshop on Waldenström Macroglobulinaemia
(Wiley, 2016-10)The diagnosis of Waldenström macroglobulinemia (WM) can be challenging given the variety of signs and symptoms patients can present. Furthermore, once the diagnosis of WM is established, the initial evaluation should be ... -
Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men
(Taylor & Francis, 2015)Hypogonadism or Testosterone Deficiency (TD) in adult men as defined by low levels of serum testosterone accompanied by characteristic symptoms and/or signs as detailed further on can be found in long-recognized clinical ... -
Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia
(Wiley, 2014-12-24)This article provides a summary statement of recommended implementations of arterial spin labeling (ASL) for clinical applications. It is a consensus of the ISMRM Perfusion Study Group and the European ‘ASL in Dementia’ ... -
Recommended Practices for Computerized Clinical Decision Support and Knowledge Management in Community Settings: A Qualitative Study
(BioMed Central, 2012)Background: The purpose of this study was to identify recommended practices for computerized clinical decision support (CDS) development and implementation and for knowledge management (KM) processes in ambulatory clinics ... -
Reconfigurable optical assembly of nanostructures
(Nature Publishing Group, 2016)Arrangements of nanostructures in well-defined patterns are the basis of photonic crystals, metamaterials and holograms. Furthermore, rewritable optical materials can be achieved by dynamically manipulating nanoassemblies. ...