Now showing items 14039-14058 of 17918

    • Recognition of Depressive Symptoms by Physicians 

      Henriques, Sergio Gonçalves; Fráguas, Renério; Iosifescu, Dan Vlad; Menezes, Paulo Rossi; de Lucia, Mara Cristina Souza; Gattaz, Wagner Farid; Martins, Milton Arruda (Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, 2009)
      OBJECTIVE: To investigate the recognition of depressive symptoms of major depressive disorder (MDD) by general practitioners. INTRODUCTION: MDD is underdiagnosed in medical settings, possibly because of difficulties in the ...
    • Recognition of Facial Expressions by Seven-Month-Old Infants 

      Nelson, Charles A.; Morse, Philip A.; Leavitt, Lewis A. (Wiley, 1979)
      3 experiments examined 7-month-old infants' ability to discriminate the facial expressions of happy vs. fear. Experiment 1 revealed that infants demonstrated discrimination of happy vs. fear expressions when posed by a ...
    • Recognition of HIV-1 Peptides by Host CTL Is Related to HIV-1 Similarity to Human Proteins 

      Rolland, Morgane; Nickle, David C.; Deng, Wenjie; Frahm, Nicole; Learn, Gerald H.; Heckerman, David; Jojic, Nebosja; Jojic, Vladimir; Mullins, James I.; Brander, Christian; Walker, Bruce David (Public Library of Science, 2007)
      Background: While human immunodeficiency virus type 1 (HIV-1)-specific cytotoxic T lymphocytes preferentially target specific regions of the viral proteome, HIV-1 features that contribute to immune recognition are not well ...
    • Recognition of Phosphodegron Motifs in Human Cyclin E by the SCF Fbw7 Ubiquitin Ligase 

      Ye, Xin; Nalepa, Grzegorz; Welcker, Markus; Kessler, Benedikt M.; Spooner, Eric; Qin, Jun; Elledge, Stephen J.; Clurman, Bruce E.; Harper, J. Wade (American Society for Biochemistry and Molecular Biology, 2004)
      Turnover of cyclin E is controlled by SCFFbw7. Three isoforms of Fbw7 are produced by alternative splicing. Whereas Fbw7alpha and -gamma are nuclear and the beta-isoform is cytoplasmic in 293T cells, all three isoforms ...
    • Recognition of the centromere-specific histone Cse4 by the chaperone Scm3 

      Cho, Uhn-Soo; Harrison, Stephen C. (National Academy of Sciences, 2011)
      A specialized nucleosome is a component of all eukaryotic kinetochores. The core of this nucleosome contains a centromere-specific histone, CENP-A (the Cse4 gene product in budding yeast), instead of the usual H3. Assembly ...
    • Recognizing and managing sepsis: what needs to be done? 

      Yealy, Donald M; Huang, David T; Delaney, Anthony; Knight, Marian; Randolph, Adrienne G; Daniels, Ron; Nutbeam, Tim (BioMed Central, 2015)
      Sepsis is associated with significant morbidity and mortality if not promptly recognized and treated. Since the development of early goal-directed therapy, mortality rates have decreased, but sepsis remains a major cause ...
    • Recognizing Delirium Superimposed on Dementia 

      Inouye, Sharon (Healio, 2007)
      Delirium is a serious and prevalent problem that occurs in many hospitalized older adults. Delirium superimposed on dementia (DSD) occurs when a delirium occurs concurrently with a pre-existing dementia. DSD is typically ...
    • Recognizing the cooperative and independent mitochondrial functions of Parkin and PINK1 

      Johnson, Bethann N.; Charan, Rakshita; LaVoie, Matthew James (Landes Bioscience, 2012)
    • Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice 

      Krishnamoorthy, Sriram; Liu, Tongyao; Drager, Douglas; Patarroyo-White, Susannah; Chhabra, Ekta Seth; Peters, Robert; Josephson, Neil; Lillicrap, David; Blumberg, Richard S.; Pierce, Glenn F.; Jiang, Haiyan (2016)
      Anti-factor VIII (FVIII) antibodies is a major complication of FVIII replacement therapy for hemophilia A. We investigated the immune response to recombinant human factor VIII Fc (rFVIIIFc) in comparison to BDD-rFVIII and ...
    • Recombinant human thrombomodulin inhibits neutrophil extracellular trap formation in vitro 

      Shimomura, Yasuyo; Suga, Mika; Kuriyama, Naohide; Nakamura, Tomoyuki; Sakai, Toshikazu; Kato, Yu; Hara, Yoshitaka; Yamashita, Chizuru; Nagasaki, Hiroshi; Kaneki, Masao; Nishida, Osamu (BioMed Central, 2016)
      The aim of this study was to investigate the effects of recombinant human-soluble thrombomodulin (rTM) on lipopolysaccharide (LPS)-induced, platelet-dependent neutrophil extracellular trap (NET) formation (NETosis). Human ...
    • Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates 

      Mire, Chad E.; Miller, Andrew; Carville, Angela; Westmoreland, Susan V.; Geisbert, Joan B.; Mansfield, Keith G.; Feldmann, Heinz; Hensley, Lisa E.; Geisbert, Thomas W. (Public Library of Science, 2012)
      The filoviruses, Marburg virus and Ebola virus, cause severe hemorrhagic fever with high mortality in humans and nonhuman primates. Among the most promising filovirus vaccines under development is a system based on recombinant ...
    • Recombinational DNA Repair in Cancer and Normal Cells: The Challenge of Functional Analysis 

      Willers, Henning; Xia, Fen; Powell, Simon N. (Hindawi Publishing Corporation, 2002)
      A major goal of current cancer research is to understand the functional consequences of mutations in recombinational DNA repair genes. The introduction of artificial recombination substrates into living cells has evolved ...
    • Recommendations for Cardiovascular Magnetic Resonance in Adults with Congenital Heart Disease from the Respective Working Groups of the European Society of Cardiology 

      Kilner, Philip J.; Geva, Tal; Kaemmerer, Harald; Trindade, Pedro T.; Schwitter, Juerg; Webb, Gary D. (Oxford University Press, 2010)
      This paper aims to provide information and explanations regarding the clinically relevant options, strengths, and limitations of cardiovascular magnetic resonance (CMR) in relation to adults with congenital heart disease ...
    • Recommendations for imaging tumor response in neurofibromatosis clinical trials 

      Dombi, E.; Ardern-Holmes, S. L.; Babovic-Vuksanovic, D.; Barker, Frederick George; Connor, S.; Evans, D. G.; Fisher, Marc; Goutagny, S.; Harris, G. J.; Jaramillo, D.; Karajannis, M. A.; Korf, B. R.; Mautner, V.; Plotkin, Scott Randall; Poussaint, Tina Young; Robertson, Kent; Shih, C.-S.; Widemann, B. C.; undefined, undefined (Ovid Technologies (Wolters Kluwer Health), 2013)
      Objective: Neurofibromatosis (NF)-related benign tumors such as plexiform neurofibromas (PN) and vestibular schwannomas (VS) can cause substantial morbidity. Clinical trials directed at these tumors have become available. ...
    • Recommendations for open data science 

      Gymrek, Melissa; Farjoun, Yossi (BioMed Central, 2016)
      Life science research increasingly relies on large-scale computational analyses. However, the code and data used for these analyses are often lacking in publications. To maximize scientific impact, reproducibility, and ...
    • Recommendations for the Diagnosis and Initial Evaluation of Patients with Waldenström Macroglobulinaemia: A Task Force from the 8th International Workshop on Waldenström Macroglobulinaemia 

      Castillo, Jorge; Garcia-Sanz, Ramon; Hatjiharissi, Evdoxia; Kyle, Robert A.; Leleu, Xavier; McMaster, Mary; Merlini, Giampaolo; Minnema, Monique C.; Morra, Enrica; Owen, Roger G.; Poulain, Stephanie; Stone, Marvin J.; Tam, Constantine; Varettoni, Marzia; Dimopoulos, Meletios A.; Treon, Steven; Kastritis, Efstathios (Wiley, 2016-10)
      The diagnosis of Waldenström macroglobulinemia (WM) can be challenging given the variety of signs and symptoms patients can present. Furthermore, once the diagnosis of WM is established, the initial evaluation should be ...
    • Recommendations on the diagnosis, treatment and monitoring of hypogonadism in men 

      Lunenfeld, Bruno; Mskhalaya, George; Zitzmann, Michael; Arver, Stefan; Kalinchenko, Svetlana; Tishova, Yuliya; Morgentaler, Abraham (Taylor & Francis, 2015)
      Hypogonadism or Testosterone Deficiency (TD) in adult men as defined by low levels of serum testosterone accompanied by characteristic symptoms and/or signs as detailed further on can be found in long-recognized clinical ...
    • Recommended implementation of arterial spin-labeled perfusion MRI for clinical applications: A consensus of the ISMRM perfusion study group and the European consortium for ASL in dementia 

      Alsop, David; Detre, John A.; Golay, Xavier; Günther, Matthias; Hendrikse, Jeroen; Hernandez-Garcia, Luis; Lu, Hanzhang; MacIntosh, Bradley J.; Parkes, Laura M.; Smits, Marion; van Osch, Matthias J. P.; Wang, Danny J. J.; Wong, Eric C.; Zaharchuk, Greg (Wiley, 2014-12-24)
      This article provides a summary statement of recommended implementations of arterial spin labeling (ASL) for clinical applications. It is a consensus of the ISMRM Perfusion Study Group and the European ‘ASL in Dementia’ ...
    • Recommended Practices for Computerized Clinical Decision Support and Knowledge Management in Community Settings: A Qualitative Study 

      Ash, Joan S; Sittig, Dean F; Guappone, Kenneth P; Dykstra, Richard H; Richardson, Joshua; Carpenter, James; McMullen, Carmit; Shapiro, Michael; Bunce, Arwen; Wright, Adam; Middleton, Blackford (BioMed Central, 2012)
      Background: The purpose of this study was to identify recommended practices for computerized clinical decision support (CDS) development and implementation and for knowledge management (KM) processes in ambulatory clinics ...
    • Reconfigurable optical assembly of nanostructures 

      Montelongo, Yunuen; Yetisen, Ali K.; Butt, Haider; Yun, Seok-Hyun (Nature Publishing Group, 2016)
      Arrangements of nanostructures in well-defined patterns are the basis of photonic crystals, metamaterials and holograms. Furthermore, rewritable optical materials can be achieved by dynamically manipulating nanoassemblies. ...