Now showing items 1569-1588 of 15665

    • Brain Changes in Responders vs. Non-Responders in Chronic Migraine: Markers of Disease Reversal 

      Hubbard, Catherine S.; Becerra, Lino; Smith, Jonathan H.; DeLange, Justin M.; Smith, Ryan M.; Black, David F.; Welker, Kirk M.; Burstein, Rami; Cutrer, Fred M.; Borsook, David (Frontiers Media S.A., 2016)
      The aim of this study was to identify structural and functional brain changes that accompanied the transition from chronic (CM; ≥15 headache days/month) to episodic (EM; <15 headache days/month) migraine following prophylactic ...
    • Brain correlates of autonomic modulation: Combining heart rate variability with fMRI 

      Napadow, Vitaly J.; Dhond, Rupali; Conti, Giulia; Makris, Nikos; Brown, Emery Neal; Barbieri, Riccardo (Elsevier BV, 2008)
      The central autonomic network (CAN) has been described in animal models but has been difficult to elucidate in humans. Potential confounds include physiological noise artifacts affecting brainstem neuroimaging data, and ...
    • Brain correlates of phasic autonomic response to acupuncture stimulation: An event-related fMRI study 

      Napadow, Vitaly J.; Lee, Jeungchan; Kim, Jieun; Cina, Stephen; Maeda, Yumi; Barbieri, Riccardo; Harris, Richard E.; Kettner, Norman; Park, Kyungmo (Wiley-Blackwell, 2012)
      Autonomic nervous system (ANS) response to acupuncture has been investigated by multiple studies; however, the brain circuitry underlying this response is not well understood. We applied event-related fMRI (er-fMRI) in ...
    • Brain encoding of acupuncture sensation — Coupling on-line rating with fMRI 

      Napadow, Vitaly J.; Dhond, Rupali P.; Kim, Jieun; LaCount, Lauren; Vangel, Mark G.; Harris, Richard E; Kettner, Norman; Park, Kyungmo (Elsevier BV, 2009)
      Acupuncture-induced sensations have historically been associated with clinical efficacy. These sensations are atypical, arising from sub-dermal receptors, and their neural encoding is not well known. In this fMRI study, ...
    • Brain endothelial cell‐targeted gene therapy of neurovascular disorders 

      Marchiò, Serena; Sidman, Richard L; Arap, Wadih; Pasqualini, Renata (John Wiley and Sons Inc., 2016)
      Neurovascular disorders are difficult to treat due to the blood–brain barrier (BBB), which prevents delivery of most drugs from the blood into the brain. Gene therapy can potentially overcome this barrier, but classical ...
    • Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity 

      Peters, Jurriaan M.; Taquet, Maxime; Vega, Clemente; Jeste, Shafali S; Fernández, Iván; Tan, Jacqueline E; Nelson, Charles A.; Sahin, Mustafa; Warfield, Simon Keith (Springer Science + Business Media, 2013)
      Background Graph theory has been recently introduced to characterize complex brain networks, making it highly suitable to investigate altered connectivity in neurologic disorders. A current model proposes autism spectrum ...
    • Brain Genomics Superstruct Project initial data release with structural, functional, and behavioral measures 

      Holmes, Avram J.; Hollinshead, Marisa O.; O’Keefe, Timothy M.; Petrov, Victor I.; Fariello, Gabriele R.; Wald, Lawrence L.; Fischl, Bruce; Rosen, Bruce R.; Mair, Ross W.; Roffman, Joshua L.; Smoller, Jordan W.; Buckner, Randy L. (Nature Publishing Group, 2015)
      The goal of the Brain Genomics Superstruct Project (GSP) is to enable large-scale exploration of the links between brain function, behavior, and ultimately genetic variation. To provide the broader scientific community ...
    • The brain imaging data structure, a format for organizing and describing outputs of neuroimaging experiments 

      Gorgolewski, Krzysztof J.; Auer, Tibor; Calhoun, Vince D.; Craddock, R. Cameron; Das, Samir; Duff, Eugene P.; Flandin, Guillaume; Ghosh, Satrajit S.; Glatard, Tristan; Halchenko, Yaroslav O.; Handwerker, Daniel A.; Hanke, Michael; Keator, David; Li, Xiangrui; Michael, Zachary; Maumet, Camille; Nichols, B. Nolan; Nichols, Thomas E.; Pellman, John; Poline, Jean-Baptiste; Rokem, Ariel; Schaefer, Gunnar; Sochat, Vanessa; Triplett, William; Turner, Jessica A.; Varoquaux, Gaël; Poldrack, Russell A. (Nature Publishing Group, 2016)
      The development of magnetic resonance imaging (MRI) techniques has defined modern neuroimaging. Since its inception, tens of thousands of studies using techniques such as functional MRI and diffusion weighted imaging have ...
    • The Brain in Schizotypal Personality Disorder: A Review of Structural MRI and CT Findings 

      Dickey, Chandlee C.; McCarley, Robert William; Shenton, Martha Elizabeth (Ovid Technologies (Wolters Kluwer Health), 2002)
      Studies of schizotypal personality disorder (SPD) are important because the condition is genetically related to schizophrenia and because data accumulating to confirm its biological underpinnings are challenging some ...
    • The BRAIN Initiative: developing technology to catalyse neuroscience discovery 

      Jorgenson, Lyric A.; Newsome, William T.; Anderson, David J.; Bargmann, Cornelia I.; Brown, Emery N.; Deisseroth, Karl; Donoghue, John P.; Hudson, Kathy L.; Ling, Geoffrey S. F.; MacLeish, Peter R.; Marder, Eve; Normann, Richard A.; Sanes, Joshua R.; Schnitzer, Mark J.; Sejnowski, Terrence J.; Tank, David W.; Tsien, Roger Y.; Ugurbil, Kamil; Wingfield, John C. (The Royal Society, 2015)
      The evolution of the field of neuroscience has been propelled by the advent of novel technological capabilities, and the pace at which these capabilities are being developed has accelerated dramatically in the past decade. ...
    • The Brain Metabolome of Male Rats across the Lifespan 

      Zheng, Xiaojiao; Chen, Tianlu; Zhao, Aihua; Wang, Xiaoyan; Xie, Guoxiang; Huang, Fengjie; Liu, Jiajian; Zhao, Qing; Wang, Shouli; Wang, Chongchong; Zhou, Mingmei; Panee, Jun; He, Zhigang; Jia, Wei (Nature Publishing Group, 2016)
      Comprehensive and accurate characterization of brain metabolome is fundamental to brain science, but has been hindered by technical limitations. We profiled the brain metabolome in male Wistar rats at different ages (day ...
    • Brain metastases in patients with EGFR -mutated or ALK -rearranged non-small-cell lung cancers 

      Rangachari, Deepa; Yamaguchi, Norihiro; Vanderlaan, Paul A; Folch, Erik E; Mahadevan, Anand; Floyd, Scott R.; Uhlmann, Erik J; Wong, Eric S.; Dahlberg, Suzanne Eleanor; Huberman, Mark S.; Costa, Daniel Botelho (Elsevier BV, 2015)
      Introduction—Brain metastases (BM) are common in non-small-cell lung cancer (NSCLC). However, the baseline incidence and evolution of BM over time in oncogene-driven NSCLCs are seldom reported. In this study, we evaluated ...
    • Brain MRI Lesion Load at 1.5T and 3T versus Clinical Status in Multiple Sclerosis 

      Stankiewicz, James; Glanz, Bonnie; Healy, Brian Curran; Arora, Ashish; Neema, Mohit; Benedict, Ralph H.B.; Guss, Zachary D.; Tauhid, Shahamat Syed; Buckle, Guy J.; Houtchens, Maria K.; Khoury, Samia Joseph; Weiner, Howard Lee; Guttmann, Charles R.G.; Bakshi, Rohit (Wiley-Blackwell, 2011)
      Background/Purpose: To assess correlation between brain lesions and clinical status with 1.5T and 3T magnetic resonance imaging (MRI). Methods: Brain MRI fluid-attenuated inversion-recovery (FLAIR) sequences were performed ...
    • Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis 

      Tauhid, Shahamat; Chu, Renxin; Sasane, Rahul; Glanz, Bonnie I.; Neema, Mohit; Miller, Jennifer R.; Kim, Gloria; Signorovitch, James E.; Healy, Brian C.; Chitnis, Tanuja; Weiner, Howard L.; Bakshi, Rohit (Springer Berlin Heidelberg, 2015)
      Multiple sclerosis (MS) commonly affects occupational function. We investigated the link between brain MRI and employment status. Patients with MS (n = 100) completed a Work Productivity and Activity Impairment (WPAI) ...
    • Brain Networks of Novelty-Driven Involuntary and Cued Voluntary Auditory Attention Shifting 

      Huang, Samantha; Belliveau, John William; Tengshe, Chinmayi; Ahveninen, Jyrki Pekka (Public Library of Science, 2012)
      In everyday life, we need a capacity to flexibly shift attention between alternative sound sources. However, relatively little work has been done to elucidate the mechanisms of attention shifting in the auditory domain. ...
    • Brain Plasticity in Blind Subjects Centralizes Beyond the Modal Cortices 

      Ortiz-Terán, Laura; Ortiz, Tomás; Perez, David L.; Aragón, Jose Ignacio; Diez, Ibai; Pascual-Leone, Alvaro; Sepulcre, Jorge (Frontiers Media S.A., 2016)
      It is well established that the human brain reorganizes following sensory deprivations. In blind individuals, visual processing regions including the lateral occipital cortex (LOC) are activated by auditory and tactile ...
    • Brain Science: From the Very Small to the Very Large 

      Kreiman, Gabriel (Elsevier BV, 2007)
    • Brain temperature and its fundamental properties: a review for clinical neuroscientists 

      Wang, Huan; Wang, Bonnie; Normoyle, Kieran P.; Jackson, Kevin; Spitler, Kevin; Sharrock, Matthew F.; Miller, Claire M.; Best, Catherine; Llano, Daniel; Du, Rose (Frontiers Media S.A., 2014)
      Brain temperature, as an independent therapeutic target variable, has received increasingly intense clinical attention. To date, brain hypothermia represents the most potent neuroprotectant in laboratory studies. Although ...
    • Brain Tumor Cells in Circulation Are Enriched for Mesenchymal Gene Expression 

      Sullivan, James P; Nahed, Brian Vala; Madden, M. W.; Oliveira, S. M.; Springer, S.; Bhere, Deepak; Chi, A. S.; Wakimoto, Hiroaki; Rothenberg, S. M.; Sequist, Lecia VanDam; Kapur, R.; Shah, Khalid A.; Iafrate, Anthony John; Curry, William Thomas; Loeffler, Jay Steven; Batchelor, Tracy Todd; Louis, David N.; Toner, Mehmet; Maheswaran, Shyamala; Haber, Daniel Arie (American Association for Cancer Research (AACR), 2014)
      Glioblastoma (GBM) is a highly aggressive brain cancer characterized by local invasion and angiogenic recruitment, yet metastatic dissemination is extremely rare. Here, we adapted a microfluidic device to deplete hematopoietic ...
    • Brain Weight Differences Associated with Induced Focal Microgyria 

      Peiffer, Ann M; Fitch, R Holly; Thomas, Jennifer Joanne; Yurkovic, Alexandra Nicole; Rosen, Glenn David (BioMed Central, 2003)
      Background: Disrupting neural migration with bilateral focal freezing necrosis on postnatal day 1 (P1) results in the formation of 4-layered microgyria. This developmental injury triggers a pervasive neural reorganization, ...