Browsing HMS Scholarly Articles by Title
Now showing items 1604-1623 of 17917
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Benign Metastatic Leiomyoma Presenting as a Hemothorax
(Hindawi Publishing Corporation, 2013)Uterine leiomyomas have been reported to metastasize to various organs including the lungs, skeletal muscles, bone marrow, peritoneum, and heart. They may present with symptoms related to the metastases several years after ... -
Benzodiazepine and Opioid Use and the Duration of Intensive Care Unit Delirium in an Older Population*
(Ovid Technologies (Wolters Kluwer Health), 2009)Objective: There is a high prevalence of delirium in older medical intensive care unit (ICU) patients and delirium is associated with adverse outcomes. We need to identify modifiable risk factors for delirium, such as ... -
Benzodiazepine Use and Hip Fractures in the Elderly
(American Medical Association (AMA), 2004) -
Benzodiazepines are Prescribed More Frequently to Patients Already at Risk for Benzodiazepine-related Adverse Events in Primary Care
(2016)Benzodiazepine use is associated with adverse drug events and higher mortality. Known risk factors for benzodiazepine-related adverse events include lung disease, substance use, and vulnerability to fracture.To determine ... -
Benzoic Acid-Inducible Gene Expression in Mycobacteria
(Public Library of Science, 2015)Conditional expression is a powerful tool to investigate the role of bacterial genes. Here, we adapt the Pseudomonas putida-derived positively regulated XylS/Pm expression system to control inducible gene expression in ... -
Berberine-INF55 (5-Nitro-2-Phenylindole) Hybrid Antimicrobials: Effects of Varying the Relative Orientation of the Berberine and INF55 Components
(American Society for Microbiology, 2010)Hybrid antimicrobials containing an antibacterial linked to a multidrug resistance (MDR) pump inhibitor make up a promising new class of agents for countering efflux-mediated bacterial drug resistance. This study explores ... -
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium
(Public Library of Science, 2013)Genotyping arrays are a cost effective approach when typing previously-identified genetic polymorphisms in large numbers of samples. One limitation of genotyping arrays with rare variants (e.g., minor allele frequency [MAF] ... -
Best Practices: Optimizing Care for People With Serious Mental Illness and Comorbid Diabetes
(American Psychiatric Publishing, 2011)Diabetes and obesity among patients with serious mental illness are common. Use of second-generation antipsychotics compounds risk, and widely prevalent unhealthy behaviors further contribute to negative outcomes. This ... -
The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease
(Frontiers Media S.A., 2014)Growth factors play important roles in synapse formation. Mouse models of neuropsychiatric diseases suggest that defects in synaptogenic growth factors, their receptors, and signaling pathways can lead to disordered neural ... -
Beta-Synemin Expression in Cardiotoxin-Injected Rat Skeletal Muscle
(BioMed Central, 2007)Background: β-synemin was originally identified in humans as an α-dystrobrevin-binding protein through a yeast two-hybrid screen using an amino acid sequence derived from exons 1 through 16 of α-dystrobrevin, a region ... -
\(\beta\)-Cell Hyperplasia Induced by Hepatic Insulin Resistance
(American Diabetes Association, 2009)Objective: Type 2 diabetes results from a combination of insulin resistance and impaired insulin secretion. To directly address the effects of hepatic insulin resistance in adult animals, we developed an inducible ... -
BETASCAN: Probable \(\beta\)-amyloids Identified by Pairwise Probabilistic Analysis
(Public Library of Science, 2009)Amyloids and prion proteins are clinically and biologically important \(\beta\)-structures, whose supersecondary structures are difficult to determine by standard experimental or computational means. In addition, significant ... -
Bethesda Categorization of Thyroid Nodule Cytology and Prediction of Thyroid Cancer Type and Prognosis
(2016)Background: Since its inception, the Bethesda System for Reporting Thyroid Cytopathology (TBS) has been widely adopted. Each category conveys a risk of malignancy and recommended next steps, though it is unclear if each ... -
Bevacizumab for Progressive Vestibular Schwannoma in Neurofibromatosis Type 2
(Ovid Technologies (Wolters Kluwer Health), 2012)Objective: Early studies suggest that bevacizumab treatment can result in tumor shrinkage and hearing improvement for some patients with neurofibromatosis type 2 (NF2). The aim of this study was to report extended follow-up ... -
Bevacizumab terminates homeobox B9-induced tumor proliferation by silencing microenvironmental communication
(BioMed Central, 2014)Background: Homeobox B9 (HOXB9), a transcriptional factor, regulates developmental processes and tumor progression and has recently been recognized as one of important transcriptional factors related to angiogenesis. This ... -
Bevacizumab Treatment for Meningiomas in NF2: A Retrospective Analysis of 15 Patients
(Public Library of Science (PLoS), 2013)Bevacizumab treatment can result in tumor shrinkage of progressive vestibular schwannomas in some neurofibromatosis 2 (NF2) patients but its effect on meningiomas has not been defined. To determine the clinical activity ... -
Bevacizumab treatment for symptomatic spinal ependymomas in neurofibromatosis type 2
(Wiley-Blackwell, 2015)Background Neurofibromatosis type 2 (NF2) is a tumor suppressor syndrome associated with vestibular schwannomas, meningiomas, and spinal ependymomas. There have been anecdotal reports of radiographic response of spinal ... -
Beyond BMI: The “Metabolically healthy obese” phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality -- a systematic review
(BioMed Central, 2014)Background: A subgroup has emerged within the obese that do not display the typical metabolic disorders associated with obesity and are hypothesized to have lower risk of complications. The purpose of this review was to ... -
Beyond Crossing Fibers: Bootstrap Probabilistic Tractography Using Complex Subvoxel Fiber Geometries
(Frontiers Media S.A., 2014)Diffusion magnetic resonance imaging fiber tractography is a powerful tool for investigating human white matter connectivity in vivo. However, it is prone to false positive and false negative results, making interpretation ... -
Beyond descriptive research: advancing the study of spirituality and health
(Springer Science + Business Media, 2011)The past three decades have witnessed a surge in research on spirituality and health. This growing body of literature has linked many aspects of spirituality as well as religion to both positive and negative indices of ...