Now showing items 2050-2069 of 15601

    • Characterisation and In Silico Analysis of Interleukin-4 cDNA of Nilgai (Boselaphus tragocamelus) and Indian Buffalo (Bubalus bubalis) 

      Saini, M.; Palai, T. K.; Das, D. K.; Hatle, K. M.; Gupta, P. K. (Hindawi Publishing Corporation, 2013)
      Interleukin-4 (IL-4) produced from Th2 cells modulates both innate and adaptive immune responses. It is a common belief that wild animals possess better immunity against diseases than domestic and laboratory animals; ...
    • Characterisation of [11C]PR04.MZ in Papio Anubis Baboon: A Selective High-Affinity Radioligand for Quantitative Imaging of the Dopamine Transporter 

      Riss, Patrick J.; Hooker, Jacob M; Shea, Colleen; Xu, Youwen; Carter, Pauline; Warner, Donald; Ferrari, Valentina; Kim, Sung-Won; Aigbirhio, Franklin I.; Fowler, Joanna S.; Roesch, Frank (Elsevier BV, 2012)
      N-(4-fluorobut-2-yn-1-yl)-2β-carbomethoxy-3β-(4′-tolyl)nortropane (PR04.MZ, 1) is a PET radioligand for the non-invasive exploration of the function of the cerebral dopamine transporter (DAT). A reliable automated process ...
    • Characteristics and Impact of Drug Detailing for Gabapentin 

      Steinman, Michael A; Harper, Gordon P.; Chren, Mary-Margaret; Landefeld, C. Seth; Bero, Lisa A (Public Library of Science, 2007)
      Background: Sales visits by pharmaceutical representatives (“drug detailing”) are common, but little is known about the content of these visits or about the impact of visit characteristics on prescribing behavior. In this ...
    • Characteristics and management of HIV-1-infected pregnant women enrolled in a randomised trial: differences between Europe and the USA 

      Newell, Marie-Louise; Fiore, Simona; Thorne, Claire; Mandelbrot, Laurent; Maupin, Robert; Delke, Isaac; Cunningham, Coleen K; Huang, Xiao Sharon; Sullivan, John L; Watts, D Heather; Gelber, Richard David (BioMed Central, 2007)
      Background: Rates of mother-to-child transmission of HIV-1 (MTCT) have historically been lower in European than in American cohort studies, possibly due to differences in population characteristics. The Pediatric AIDS ...
    • Characteristics and Outcomes of Initial Virologic Suppressors during Analytic Treatment Interruption in a Therapeutic HIV-1 \(gag\) Vaccine Trial 

      Brumme, Chanson J.; Lederman, Michael M.; Brumme, Zabrina L.; Wang, Hongying; Carrington, Mary; Medvik, Kathleen; Schooley, Robert T.; Li, Jonathan Zheng; Spritzle, John; Walker, Bruce David; Kuritzkes, Daniel Robert (Public Library of Science, 2012)
      Background: In the placebo-controlled trial ACTG A5197, a trend favoring viral suppression was seen in the HIV-1-infected subjects who received a recombinant Ad5 HIV-1 \(gag\) vaccine. Objective: To identify individuals ...
    • Characteristics and Patterns of Metastatic Disease from Chordoma 

      Young, Victoria A.; Curtis, Kevin M.; Temple, H. Thomas; Eismont, Frank J.; DeLaney, Thomas F.; Hornicek, Francis J. (Hindawi Publishing Corporation, 2015)
      Chordoma is a rare, slow-growing malignant tumor arising from notochordal remnants. A retrospective review of patient records at two major referral centers was undertaken to assess the incidence, location, and prognostic ...
    • Characteristics and Predictive Value of Blood Transcriptome Signature in Males with Autism Spectrum Disorders 

      Kong, Sek Won; Collins, Christin D.; Shimizu-Motohashi, Yuko; Holm, Ingrid A.; Campbell, Malcolm G.; Lee, In-Hee; Brewster, Stephanie J.; Hanson, Ellen M.; Harris, Heather; Lowe, Kathryn R.; Saada, Adrianna; Mora, Andrea; Madison, Kimberly; Hundley, Rachel; Egan, Jessica; McCarthy, Jillian; Eran, Ally; Galdzicki, Michal; Rappaport, Leonard; Kunkel, Louis M.; Kohane, Isaac S. (Public Library of Science, 2012)
      Autism Spectrum Disorders (ASD) is a spectrum of highly heritable neurodevelopmental disorders in which known mutations contribute to disease risk in 20% of cases. Here, we report the results of the largest blood transcriptome ...
    • Characteristics Associated With Delirium in Older Patients in a Medical Intensive Care Unit 

      Pisani, Margaret A.; Murphy, Terrence; Van Ness, Peter; Araujo, Katy; Inouye, Sharon (American Medical Association (AMA), 2007)
      Background Delirium is a highly prevalent disorder among older patients in the intensive care unit. Methods We performed a prospective cohort study of 304 patients 60 years or older admitted from September 5, 2002, ...
    • Characteristics of Freebase Cocaine Psychosis. 

      Manschreck, Theo Clyde; Laughery, Judy A.; Weisstein, C. Cecily; Allen, David; Humblestone, Brian; Neville, Michael; Podlewski, Henry; Mitra, Nina (Yale Journal of Biology and Medicine, 1988)
      Psychosis was present in 29 percent of cocaine-disordered patients hospitalized in 1985 during an epidemic of freebase cocaine abuse in the Bahamas. Record reviews revealed that a variety of psychotic phenomenologic patterns ...
    • Characteristics of HCV Co-Infection among HIV Infected Individuals from an Area with High Risk of Blood-Borne Infections in Central China 

      Zhang, Tiejun; Tully, Damien C.; Zhou, Sujuan; He, Na (Public Library of Science, 2014)
      Objective: Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) co-infection has been proved to be a growing public health concern. The prevalence and genotypic pattern vary with geographic locations. Limited ...
    • Characteristics of individuals not visiting their primary care provider 

      Bitton, Asaf; Dugani, Sagar B (BioMed Central, 2014)
      The observational study by Rosen and colleagues described the proportion and characteristics of individuals who do not visit their primary care physician regularly. Overall, they identify a very low rate of non-attendance, ...
    • Characteristics of Inflammatory Bowel Disease Serology in Patients With Indeterminate Colitis 

      Sura, Siddharth P.; Ahmed, Awais; Cheifetz, Adam S.; Moss, Alan C (Ovid Technologies (Wolters Kluwer Health), 2014)
      Goals and Background Inflammatory bowel disease (IBD) serology testing is often used in patients with indeterminate colitis (IC) to help distinguish between ulcerative colitis (UC) and Crohn’s disease (CD). We investigated ...
    • Characteristics of Patients Presenting to the Emergency Department and Urgent Care for Treatment of Sunburn 

      Di Xia, Fan; Fuhlbrigge, Mary; Waul, Michael Andrew; Joyce, Cara; Mostaghimi, Arash (American Medical Association (AMA), 2017)
      Sunburn led to an estimated 33 826 visits to US emergency departments (EDs) in 2013, resulting in a cost of $11.2 million. Despite this burden, little is known about the features of patients utilizing the ED or urgent care ...
    • Characteristics of Responders to Cardiac Resynchronization Therapy: The Impact of Echocardiographic Left Ventricular Volume 

      Park, Mi Young; Altman, Robert K.; Orencole, Mary; Kumar, Prabhat; Parks, Kimberly Ann; Heist, Kevin E.; Singh, Jagmeet P.; Picard, Michael Howard (Wiley-Blackwell, 2012)
      Background: One third of patients who receive cardiac resynchronization therapy (CRT) are classified as nonresponders. Characteristics of responders to CRT have been studied in multiple clinical trials. Hypothesis: We aimed ...
    • Characteristics of stable chronic obstructive pulmonary disease patients in the pulmonology clinics of seven Asian cities 

      Oh, Yeon-Mok; Bhome, Arvind B; Boonsawat, Watchara; Gunasekera, Kirthi Dias; Madegedara, Dushantha; Idolor, Luisito; Roa, Camilo; Kim, Woojin; Kuo, Han-Pin; Wang, Chun-Hua; Lan, Le Thi Tuyet; Loh, Li-Cher; Ong, Choo-Khoon; Ng, Alan; Nishimura, Masaharu; Makita, Hironi; Silverman, Edwin K; Lee, Jae Seung; Yang, Ting; Lin, Yingxiang; Wang, Chen; Lee, Sang-Do (Dove Medical Press, 2013)
      Background and objectives Chronic obstructive pulmonary disease (COPD) is responsible for significant morbidity and mortality worldwide. We evaluated the characteristics of stable COPD patients in the pulmonology clinics ...
    • Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1 

      Mikell, Iliyana; Sather, D. Noah; Kalams, Spyros A.; Altfeld, Marcus; Alter, Galit; Stamatatos, Leonidas (Public Library of Science, 2011)
      Recent cross-sectional analyses of HIV-1+ plasmas have indicated that broadly cross-reactive neutralizing antibody responses are developed by 10%–30% of HIV-1+ subjects. The timing of the initial development of such ...
    • Characteristics of two different locking compression plates in the volar fixation of complex articular distal radius fractures 

      von Recum, J.; Matschke, S.; Jupiter, Jesse Bernard; Ring, David; Souer, J-S.; Huber, M.; Audigé, L. (British Editorial Society of Bone and Joint Surgery, 2012)
      Objectives: To investigate the differences of open reduction and internal fixation (ORIF) of complex AO Type C distal radius fractures between two different models of a single implant type. Methods: A total of 136 patients ...
    • Characteristics of Walkable Built Environments and BMI z-Scores in Children: Evidence from a Large Electronic Health Record Database 

      Duncan, Dustin T.; Sharifi, Mona; Melly, Steven J.; Marshall, Richard; Sequist, Thomas D.; Rifas-Shiman, Sheryl L.; Taveras, Elsie M. (NLM-Export, 2014)
      Background: Childhood obesity remains a prominent public health problem. Walkable built environments may prevent excess weight gain. Objectives: We examined the association of walkable built environment characteristics ...
    • Characterization of a Drosophila Alzheimer's Disease Model: Pharmacological Rescue of Cognitive Defects 

      Chakraborty, Ranjita; Vepuri, Vidya; Mhatre, Siddhita D.; Paddock, Brie E.; Miller, Sean; Michelson, Sarah J.; Delvadia, Radha; Desai, Arkit; Vinokur, Marianna; Melicharek, David J.; Utreja, Suruchi; Khandelwal, Preeti; Ansaloni, Sara; Lee, Jeremy C.; Tabb, Loni P.; Saunders, Aleister J.; Marenda, Daniel R.; Goldstein, Lee E.; Moir, Robert D. (Public Library of Science, 2011)
      Transgenic models of Alzheimer's disease (AD) have made significant contributions to our understanding of AD pathogenesis, and are useful tools in the development of potential therapeutics. The fruit fly, Drosophila ...
    • Characterization of a novel fusion gene EML4-NTRK3 in a case of recurrent congenital fibrosarcoma 

      Tannenbaum-Dvir, Sarah; Glade Bender, Julia L.; Church, Alanna J.; Janeway, Katherine A.; Harris, Marian H.; Mansukhani, Mahesh M.; Nagy, Peter L.; Andrews, Stuart J.; Murty, Vundavalli V.; Kadenhe-Chiweshe, Angela; Connolly, Eileen P.; Kung, Andrew L.; Dela Cruz, Filemon S. (Cold Spring Harbor Laboratory Press, 2015)
      Abstract We describe the clinical course of a recurrent case of congenital fibrosarcoma diagnosed in a 9-mo-old boy with a history of hemimelia. Following complete surgical resection of the primary tumor, the patient ...