Browsing HMS Scholarly Articles by Title
Now showing items 6294-6313 of 17922
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First-Episode of Synthetic Cannabinoid-Induced Psychosis in a Young Adult, Successfully Managed with Hospitalization and Risperidone
(Hindawi Publishing Corporation, 2016)Synthetic cannabinoids- (SCs-) induced psychosis is a growing public health concern. It leads to significant impairment, including emotional distress, difficulty communicating, and other debilitating symptoms. In this case ... -
First-Episode Schizophrenic Psychosis Differs From First-Episode Affective Psychosis and Controls in P300 Amplitude Over Left Temporal Lobe
(American Medical Association (AMA), 1998)Background: Schizophrenia is associated with central (sagittal) midline reductions of the P300 cognitive event-related potential and topographic asymmetry of P300, with reduced left temporal voltage. This P300 asymmetry ... -
A First-Generation Multi-Functional Cytokine for Simultaneous Optical Tracking and Tumor Therapy
(Public Library of Science, 2012)Creating new molecules that simultaneously enhance tumor cell killing and permit diagnostic tracking is vital to overcoming the limitations rendering current therapeutic regimens for terminal cancers ineffective. Accordingly, ... -
First-principles simulations of ionic molecular solids: The phase transitions inK2SeO4
(American Physical Society (APS), 1990)We present a new approach to first-principles simulations of the statics and dynamics of ionic molecular crystals. It is shown that the new method gives very realistic simulations of the phase transitions in K2Se04 and ... -
First-principles study of phase transitions inKNO3
(American Physical Society (APS), 1991)We report a first-principles simulation study of phase transitions in KNO3, using our recently developed method for treating ionic molecular solids. With the interionic potentials calculated from ab initio electron charge ... -
First-principles study of the lattice dynamics ofK2SO4
(American Physical Society (APS), 1991)Using a newly developed first-principles approach to simulations of ionic molecular crystals, we performed static relaxation, molecular-dynamics simulation, and lattice-dynamics calculations, and measurements of the Raman ... -
First-Trimester Follistatin-Like-3 Levels in Pregnancies Complicated by Subsequent Gestational Diabetes Mellitus
(American Diabetes Association, 2009)Objective: To determine whether maternal levels of follistatin-like-3 (FSTL3), an inhibitor of activin and myostatin involved in glucose homeostasis, are altered in the first trimester of pregnancies complicated by subsequent ... -
First-Trimester Urine Concentrations of Phthalate Metabolites and Phenols and Placenta miRNA Expression in a Cohort of U.S. Women
(National Institute of Environmental Health Sciences, 2015)Background: There is increasing concern that early-life exposure to endocrine-disrupting chemicals (EDCs) can influence the risk of disease development. Phthalates and phenols are two classes of suspected EDCs that are ... -
Fiscal difficulties of cities, the labor market, and health care
(Cambridge University Press (CUP), 2018-12-19)We investigated labor force and health outcomes in cities experiencing fiscal difficulties to assess how those difficulties might impact their employees. We matched 23 cities with bond downgrades and 31 cities with stable ... -
FishFace: interactive atlas of zebrafish craniofacial development at cellular resolution
(BioMed Central, 2013)Background: The vertebrate craniofacial skeleton may exhibit anatomical complexity and diversity, but its genesis and evolution can be understood through careful dissection of developmental programs at cellular resolution. ... -
The Fission Yeast COP9/signalosome Is Involved in Cullin Modification by Ubiquitin-related Ned8p
(BioMed Central, 2001)Background: The function of the fission yeast cullins Pcu1p and Pcu4p requires modification by the ubiquitin-related peptide Ned8p. A recent report by Lyapina et al. shows that the COP9/signalosome (CSN), a multifunctional ... -
A Fit-Fat Index for Predicting Incident Diabetes in Apparently Healthy Men: A Prospective Cohort Study
(Public Library of Science, 2016)Background: The purpose of this study was to examine the impact of combined cardiorespiratory fitness and waist-to-height ratio in the form of a fit-fat index on incident diabetes risk. Additionally, the independent ... -
A Fitness Index for Transplantation of Machine-Perfused Cadaveric Rat Livers
(BioMed Central, 2012)Background: The 110,000 patients currently on the transplant waiting list reflect the critical shortage of viable donor organs. However, a large pool of unused organs, from donors after cardiac death (DCD) that are ... -
The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing
(Public Library of Science, 2014)Viral immune evasion by sequence variation is a major hindrance to HIV-1 vaccine design. To address this challenge, our group has developed a computational model, rooted in physics, that aims to predict the fitness landscape ... -
Five components of the ethylene-response pathway identified in a screen for weak ethylene-insensitive mutants in Arabidopsis
(National Academy of Sciences, 2003)Five ethylene-insensitive loci (wei1-wei5) were identified by using a low-dose screen for "weak" ethylene-insensitive mutants. wei1, wei2, and wei3 seedlings showed hormone insensitivity only in roots, whereas wei4 and ... -
Five Features Of Value-Based Insurance Design Plans Were Associated With Higher Rates Of Medication Adherence
(Health Affairs (Project Hope), 2014)Value-based insurance design (VBID) plans selectively lower cost sharing to increase medication adherence. Existing plans have been structured in a variety of ways, and these variations could influence the effectiveness ... -
Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site
(American Society for Microbiology, 2016)Nanobodies, or VHHs, that recognize poliovirus type 1 have previously been selected and characterized as candidates for antiviral agents or reagents for standardization of vaccine quality control. In this study, we present ... -
The five-factor model in schizotypal personality disorder
(Elsevier BV, 2005)Studies of the five-factor model of personality in schizotypal personality disorder (SPD) have produced inconsistent results, particularly with respect to openness. In the present study, the NEO-FFI was used to measure ... -
Fixing DNA breaks during class switch recombination
(Rockefeller University Press, 2008)Immunoglobulin (Ig) class switch recombination (CSR) involves the breakage and subsequent repair of two DNA sequences, known as switch (S) regions, which flank IgH constant region exons. The resolution of CSR-associated ... -
FLAG Assay as a Novel Method for Real-Time Signal Generation During PCR: Application to Detection and Genotyping of KRAS Codon 12 Mutations
(Oxford University Press, 2007)Real-time signal generation methods for detection and characterization of low-abundance mutations in genomic DNA are powerful tools for cancer diagnosis and prognosis. Mutations in codon 12 of the oncogene KRAS, for example, ...