Browsing HMS Scholarly Articles by Keyword "APPPS1 transgenic mice"
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Clustering of plaques contributes to plaque growth in a mouse model of Alzheimer’s disease
(Springer Berlin Heidelberg, 2013)Amyloid-β (Aβ) plaque deposition plays a central role in the pathogenesis of Alzheimer’s disease (AD). Post-mortem analysis of plaque development in mouse models of AD revealed that plaques are initially small, but then ...