Browsing HMS Scholarly Articles by Keyword "Acute lung injury"
Now showing items 1-4 of 4
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Carbon Monoxide: Present and Future Indications for a Medical Gas
(The Korean Association of Internal Medicine, 2013)Gaseous molecules continue to hold new promise in molecular medicine as experimental and clinical therapeutics. The low molecular weight gas carbon monoxide (CO), and similar gaseous molecules (e.g., \(H_2S\), nitric oxide) ... -
Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome
(Springer, 2014)Background: Despite advances in supportive care, moderate-severe acute respiratory distress syndrome (ARDS) is associated with high mortality rates, and novel therapies to treat this condition are needed. Compelling ... -
Moderate Peep After Tracheal Lipopolysaccharide Instillation Prevents Inflammation and Modifies the Pattern of Brain Neuronal Activation
(Lippincott Williams & Wilkins, 2015)ABSTRACT Background: Ventilatory strategy and specifically positive end-expiratory pressure (PEEP) can modulate the inflammatory response and pulmonary-to-systemic translocation of lipopolysaccharide (LPS). Both inflammation ... -
Reduced pulmonary blood flow in regions of injury 2 hours after acid aspiration in rats
(BioMed Central, 2015)Background: Aspiration-induced lung injury can decrease gas exchange and increase mortality. Acute lung injury following acid aspiration is characterized by elevated pulmonary blood flow (PBF) in damaged lung areas in the ...