Now showing items 1-2 of 2

    • Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor suppressor activities 

      Kagawa, Shingo; Natsuizaka, Mitsuteru; Whelan, Kelly A.; Facompre, Nicole; Naganuma, Seiji; Ohashi, Shinya; Kinugasa, Hideaki; Egloff, Ann Marie; Basu, Devraj; Gimotty, Phyllis A.; Klein-Szanto, Andres J; Bass, Adam; Wong, Kwok-Kin; Diehl, J. Alan; Rustgi, Anil K.; Nakagawa, Hiroshi (2014)
      Notch activity regulates tumor biology in a context-dependent and complex manner. Notch may act as an oncogene or a tumor suppressor gene even within the same tumor type. Recently, Notch signaling has been implicated in ...
    • Direct Identification of an HPV-16 Tumor Antigen from Cervical Cancer Biopsy Specimens 

      Keskin, Derin Benerci; Reinhold, Bruce B.; Lee, Sun Young; Zhang, Guanglan; Lank, Simon; O’Connor, David H.; Berkowitz, Ross Stuart; Brusic, Vladimir; Kim, Seung Jo; Reinherz, Ellis Leonard (Frontiers Research Foundation, 2011)
      Persistent infection with high-risk human papilloma viruses (HPV) is the worldwide cause of many cancers, including cervical, anal, vulval, vaginal, penile, and oropharyngeal. Since T cells naturally eliminate the majority ...