Browsing HMS Scholarly Articles by Keyword "airway smooth muscle"

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    • Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice 

      Hiorns, Jonathan E.; Bidan, Cécile M.; Jensen, Oliver E.; Gosens, Reinoud; Kistemaker, Loes E. M.; Fredberg, Jeffrey J.; Butler, Jim P.; Krishnan, Ramaswamy; Brook, Bindi S. (Frontiers Media S.A., 2016)
      The precision-cut lung slice (PCLS) is a powerful tool for studying airway reactivity, but biomechanical measurements to date have largely focused on changes in airway caliber. Here we describe an image processing tool ...

    • Mast cell-derived neurotrophin 4 mediates allergen-induced airway hyperinnervation in early life 

      Patel, Kruti R.; Aven, Linh; Shao, Fengzhi; Krishnamoorthy, Nandini; Duvall, Melody G.; Levy, Bruce D.; Ai, Xingbin (2016)
      Asthma often progresses from early episodes of insults. How early life events connect to long-term airway dysfunction remains poorly understood. We demonstrated previously that increased neurotrophin 4 (NT4) levels following ...