Browsing HMS Scholarly Articles by Keyword "alternative splicing"

Now showing items 1-2 of 2

    • Quantitative Trait Locus and Brain Expression of HLA-DPA1 Offers Evidence of Shared Immune Alterations in Psychiatric Disorders 

      Morgan, Ling Z.; Rollins, Brandi; Sequeira, Adolfo; Byerley, William; DeLisi, Lynn E.; Schatzberg, Alan F.; Barchas, Jack D.; Myers, Richard M.; Watson, Stanley J.; Akil, Huda; Bunney, William E.; Vawter, Marquis P. (2016)
      Genome-wide association studies of schizophrenia encompassing the major histocompatibility locus (MHC) were highly significant following genome-wide correction. This broad region implicates many genes including the MHC ...

    • Therapeutic potential of targeting microRNA‐10b in established intracranial glioblastoma: first steps toward the clinic 

      Teplyuk, Nadiya M; Uhlmann, Erik J; Gabriely, Galina; Volfovsky, Natalia; Wang, Yang; Teng, Jian; Karmali, Priya; Marcusson, Eric; Peter, Merlene; Mohan, Athul; Kraytsberg, Yevgenya; Cialic, Ron; Chiocca, E Antonio; Godlewski, Jakub; Tannous, Bakhos; Krichevsky, Anna M (John Wiley and Sons Inc., 2016)
      Abstract MicroRNA‐10b (miR‐10b) is a unique oncogenic miRNA that is highly expressed in all GBM subtypes, while absent in normal neuroglial cells of the brain. miR‐10b inhibition strongly impairs proliferation and survival ...