Browsing HMS Scholarly Articles by Keyword "antigen presentation"
Now showing items 1-5 of 5
-
The Extended Family of CD1d-Restricted NKT Cells: Sifting through a Mixed Bag of TCRs, Antigens, and Functions
(Frontiers Media S.A., 2015)Natural killer T (NKT) cells comprise a family of specialized T cells that recognize lipid antigens presented by CD1d. Based on their T cell receptor (TCR) usage and antigen specificities, CD1d-restricted NKT cells have ... -
Heat Shock Proteins: Conditional Mediators of Inflammation in Tumor Immunity
(Frontiers Research Foundation, 2012)Heat shock protein (HSP)-based anticancer vaccines have undergone successful preclinical testing and are now entering clinical trial. Questions still remain, however regarding the immunological properties of HSPs. It is ... -
Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic Implications
(Frontiers Media S.A., 2015)As a single receptor, the neonatal Fc receptor (FcRn) is critically involved in regulating albumin and IgG serum concentrations by protecting these two ligands from degradation. In addition to these essential homeostatic ... -
The Role of FcRn in Antigen Presentation
(Frontiers Media S.A., 2014)Immunoglobulins are unique molecules capable of simultaneously recognizing a diverse array of antigens and themselves being recognized by a broad array of receptors. The abundance specifically of the IgG subclass and the ... -
T Lymphocyte–Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity
(Frontiers Media S.A., 2015)Antigen-specific immunity requires regulated trafficking of T cells in and out of diverse tissues in order to orchestrate lymphocyte development, immune surveillance, responses, and memory. The endothelium serves as a ...