Browsing HMS Scholarly Articles by Keyword "autoimmune disease"

Now showing items 1-3 of 3

    • Generation and Regulation of CD8+ Regulatory T Cells 

      Lu, Linrong; Cantor, Harvey (Nature Publishing Group, 2008)
      Research into the suppressive activity of CD4+FoxP3+ T regulatory cells (Treg) has defined a sublineage of CD4+ cells that contribute to self-tolerance and resistance to autoimmune disease. Much less attention has been ...

    • Targeting Syk in Autoimmune Rheumatic Diseases 

      Deng, Guo-Min; Kyttaris, Vasileios C.; Tsokos, George C. (Frontiers Media S.A., 2016)
      Spleen tyrosine kinase (Syk) is a member of the Src family of non-receptor tyrosine kinases, which associates directly with surface receptors, including B-cell receptor and Fcγ receptor, and is involved in a variety of ...

    • TNF Receptor 2 and Disease: Autoimmunity and Regenerative Medicine 

      Faustman, Denise L.; Davis, Miriam (Frontiers Media S.A., 2013)
      The regulatory cytokine tumor necrosis factor (TNF) exerts its effects through two receptors: TNFR1 and TNFR2. Defects in TNFR2 signaling are evident in a variety of autoimmune diseases. One new treatment strategy for ...