Browsing HMS Scholarly Articles by Keyword "ALS"
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Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach
(Korean Society for Molecular and Cellular Biology, 2015)Autophagy is a lysosome-dependent intracellular degradation process that allows recycling of cytoplasmic constituents into bioenergetic and biosynthetic materials for maintenance of homeostasis. Since the function of ... -
ER stress and unfolded protein response in amyotrophic lateral sclerosis—a controversial role of protein disulphide isomerase
(Frontiers Media S.A., 2014)Accumulation of proteins in aberrant conformation occurs in many neurodegenerative diseases. Furthermore, dysfunctions in protein handling in endoplasmic reticulum (ER) and the following ER stress have been implicated in ...