Browsing HMS Scholarly Articles by Keyword "Amyotrophic lateral sclerosis"

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    • Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28 

      Zürcher, Nicole R.; Loggia, Marco L.; Lawson, Robert; Chonde, Daniel B.; Izquierdo-Garcia, David; Yasek, Julia E.; Akeju, Oluwaseun; Catana, Ciprian; Rosen, Bruce R.; Cudkowicz, Merit E.; Hooker, Jacob M.; Atassi, Nazem (Elsevier, 2015)
      Evidence from human post mortem, in vivo and animal model studies implicates the neuroimmune system and activated microglia in the pathology of amyotrophic lateral sclerosis. The study aim was to further evaluate in vivo ...

    • TDP-43 Proteinopathy and Motor Neuron Disease in Chronic Traumatic Encephalopathy 

      McKee, Ann C.; Gavett, Brandon E.; Stern, Robert A.; Nowinski, Christopher J.; Cantu, Robert C.; Kowall, Neil William; Perl, Daniel P.; Hedley-Whyte, E. Tessa; Price, Bruce Heimburger; Sullivan, Chris; Morin, Peter; Lee, Hyo-Soon; Kubilus, Caroline A.; Daneshvar, Daniel H.; Wulff, Megan; Budson, Andrew E. (Oxford University Press (OUP), 2010)
      Epidemiological evidence suggests that the incidence of amyotrophic lateral sclerosis is increased in association with head injury. Repetitive head injury is also associated with the development of chronic traumatic ...