Browsing HMS Scholarly Articles by Keyword "Atrophy"
Now showing items 1-3 of 3
-
ATP1A3 Mutation in Adult Rapid-Onset Ataxia
(Public Library of Science, 2016)A 21-year old male presented with ataxia and dysarthria that had appeared over a period of months. Exome sequencing identified a de novo missense variant in ATP1A3, the gene encoding the α3 subunit of Na,K-ATPase. Several ... -
Renal Medullary and Cortical Correlates in Fibrosis, Epithelial Mass, Microvascularity, and Microanatomy Using Whole Slide Image Analysis Morphometry
(Public Library of Science, 2016)Renal tubulointerstitial injury often leads to interstitial fibrosis and tubular atrophy (IF/TA). IF/TA is typically assessed in the renal cortex and can be objectively quantitated with computerized image analysis (IA). ... -
T1- vs. T2-based MRI measures of spinal cord volume in healthy subjects and patients with multiple sclerosis
(BioMed Central, 2015)Background: The reliable and efficient measurement of spinal cord atrophy is of growing interest in monitoring disease progression in multiple sclerosis (MS). Methods: We compared T1- and T2-weighted MRI for measuring ...