Browsing HMS Scholarly Articles by Keyword "Bcl2"

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    • Leukemic survival factor SALL4 contributes to defective DNA damage repair 

      Wang, Fei; Gao, Chong; Lu, Jiayun; Tatetsu, Hiro; Williams, David A.; Müller, Lars U; Cui, Wei; Chai, Li (2016)
      SALL4 is aberrantly expressed in human myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). We have generated a SALL4 transgenic (SALL4B Tg) mouse model with pre-leukemic MDS-like symptoms that transform to ...