Browsing HMS Scholarly Articles by Keyword "Cell Surface Molecules"
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Cathepsin S Signals via PAR2 and Generates a Novel Tethered Ligand Receptor Agonist
(Public Library of Science, 2014)Protease-activated receptor-2 is widely expressed in mammalian epithelial, immune and neural tissues. Cleavage of PAR2 by serine proteases leads to self-activation of the receptor by the tethered ligand SLIGRL. The ... -
Identification of Cytolytic CD161\(^−\)CD56\(^+\) Regulatory CD8 T Cells in Human Peripheral Blood
(Public Library of Science, 2013)We previously developed methods for establishing CD8 regulatory T cell (Treg) clones from normal human peripheral blood and demonstrated that these clones were capable of killing T cell receptor (TCR)-activated autologous ...