Browsing HMS Scholarly Articles by Keyword "E7"
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Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor suppressor activities
(2014)Notch activity regulates tumor biology in a context-dependent and complex manner. Notch may act as an oncogene or a tumor suppressor gene even within the same tumor type. Recently, Notch signaling has been implicated in ... -
Direct Identification of an HPV-16 Tumor Antigen from Cervical Cancer Biopsy Specimens
(Frontiers Research Foundation, 2011)Persistent infection with high-risk human papilloma viruses (HPV) is the worldwide cause of many cancers, including cervical, anal, vulval, vaginal, penile, and oropharyngeal. Since T cells naturally eliminate the majority ...